HGS unveils positive QOL results from Phase 2B trial of Albuferon for ...(ing peginterferon alfa-2a. At week 12 on...),Health

Date:11/5/2007

ing peginterferon alfa-2a. At week 12, only 4.2% of patients taking Albuferon 900 mcg every two weeks had missed 7 or more days of work the previous month, compared with 18.1% of peginterferon alfa-2a patients (p<.05). At week 24, only 5.3% of Albuferon 900-mcg patients had missed 7 or more days of work the previous month, compared with 20.3% of peginterferon alfa-2a patients (p<.05). At Week 12, working patients taking Albuferon 900-mcg every two weeks reported missing an average of 1.1 days of work during the previous month, while peginterferon alfa-2a patients reported missing an average of 4.3 work days (p<.05). At Week 24, Albuferon 900-mcg patients had missed an average of 1.6 days of work during the previous month, while peginterferon alfa-2a patients had missed an average of 4.7 work days.

At Weeks 12 and 24, the treatment group taking Albuferon 900 mcg every two weeks also reported better scores for all eight SF-36 physical and mental health domains, as well as the physical and mental summary scores, compared with peginterferon alfa-2a. Statistically significant and clinically meaningful differences were observed in the mental health, bodily pain, vitality and social functioning domains. By the Week 12 follow-up visit after the end of treatment, changes in mental health as measured by the Hospital Anxiety and Depression Scale (HADS) had recovered to baseline in 67% of the patients taking Albuferon 900 mcg, compared with 57% of the peginterferon alfa-2a patients.

The treatment group taking Albuferon 1200 mcg every two weeks also recorded fewer lost days of work and less impairment of health-related quality of life on treatment than was reported for the peginterferon alfa-2a group.

'/>"/>

Contact: Jerry Parrott 301-315-2777 Edelman Public Relations Source:Eurekalert

0 GOOD

Page: 1 2 3
Related medicine news :

1. ARIZONA METH PROJECT Unveils Arizonas Anti-Meth Youth Pledge and Kicks Off Phase Two of Public Awareness Campaign
2. Wellcorps International Unveils New Nutritional Supplements
3. The Village Company Unveils Natural Bath and Body Solutions for Everyday Ailments
4. Rice unveils $100 million initiative for world health technology
5. Medco Unveils Three New Medicare Prescription Drug Plan Options for 2008 to Provide Seniors More Choice, Better Value and Specialist Pharmacists
6. The Well Life Center in Mesa Unveils The 10 Healing Secrets to Health & Longevity Lecture. Proceeds Benefit The Arizona Special Olympics
7. Cleveland Clinic Unveils Top 10 Medical Innovations For 2008
8. National Domestic Violence Hotline Unveils 10-Year Blueprint to Significantly Reduce Domestic Violence in America
9. GainSpan Unveils Wi-Fi(R) Sensor Network Solution With Years of Battery Life
10. U.S. Unveils Database of Genetic, Clinical Research
11. Saks Fifth Avenue Unveils Five Magical Holiday Gifts