Navigation Links
HCV and HBV spreading more slowly among injection drug users in San Francisco
Date:9/5/2007

Injection drug users are still at a very high risk of acquiring hepatitis C (HCV) and hepatitis B (HBV); however, needle-sharing is less common, and users do not become infected as quickly as they did in the past, according to a new study in the September issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience (http://www.interscience.wiley.com/journal/hepatology).

Both HCV and HBV raise the risk of liver cancer and other life-threatening liver disease and past studies have shown that most injection drug users became infected with both viruses soon after they take up the habit. To address this danger, groups have implemented interventions such as needle exchange programs for at-risk populations. Recently, researchers sought to determine what effect such interventions may have had, by determining the current prevalence and patterns of acquisition of those diseases among injection drug users. The investigation was led by Fan-Chen Tseng and Thomas R. OBrien of the National Cancer Institute, and Brian R. Edlin of Weill Cornell Medical Colleges Center for the Study of Hepatitis C and the former Director of the Urban Health Study at the University of California, San Francisco.

They used data from the Urban Health Study, which recruited injection drug users in the San Francisco Bay area from 1986 to 2005. That study collected demographic information along with blood samples which were analyzed for seroprevalence of blood-borne infections. Tseng and colleagues focused on HCV and HBV antibody prevalence in users who participated between 1998 and 2000 and compared them to those of users who participated in 1987.

Of the 2,296 drug users included in the Urban Health Study between 1998 and 2000, 91 percent had antibody to HCV and 80 percent to HBV. However, those who had recently started injecting drugs had far lower rates. Only 47 percent of participants who had been injecting drugs for less than two years were infected with HCV, compared to 71 percent who had been using for 6-9 years. Comparable rates among the 1987 population were 76 percent and 91 percent.

For HBV, about 5 percent of the population had serologic evidence of vaccination against the virus. Among the others, 41 percent of those who had injected drugs for less than 2 years, and 57 percent of those who had been using for 6-9 years were infected. Comparable rates among the 1987 population were 45 percent and 80 percent.

Only 34 percent of the participants from 1998-2000 said they had shared syringes in the past 30 days, compared to about 59 percent who had done so in 1987.

Although the population examined in this study was not a random sample, and the authors had no way to pinpoint the reasons for the improvements over time, the reductions in infection rates the authors observed coincided with the institution of street-based outreach, HIV counseling and testing, and needle exchange programs.

The findings suggest that there is now a longer window of opportunity for interventions among this at-risk population. To reduce infection rates further, the authors suggest, it is also of paramount importance to reduce the number of people who start injection drug use and to make substance abuse treatment available to those who wish to stop.

The authors conclude, It is encouraging that the frequency of HCV and HBV appears to have decreased markedly among new initiates to injection drug use in the San Francisco Bay area. If the reductions in the prevalence of these infections can be sustained, the risk of end stage liver disease and liver cancer should decrease in this population.


'/>"/>

Contact: Amy Molnar
amolnar@wiley.com
John Wiley & Sons, Inc.
Source:Eurekalert

Related medicine news :

1. Spreading its wings
2. Stopping Prostate Cancer from Spreading
3. SARS (Bird Flu) spreading in the Asian continent
4. Spreading knowledge to doctors about herbal medicine
5. Brain Fever or Encephalitis Spreading in North India
6. Bird Flu Spreading in Chinas Poultry
7. Man Convicted For Spreading HIV
8. Bird flu virus spreading in Vietnam
9. Australian Court Finds Man Guilty of Spreading HIV/AIDS
10. Music Helps in Spreading AIDS Awareness
11. Papua New Guinea MP To Face Trial For Spreading HIV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2017)... ... May 24, 2017 , ... If you are thinking of a visit to San ... architecture, October is the perfect time to visit. , Business Architecture Associates is pleased to ... offering for individuals, as a 4-½ day package for individuals, and as 4-½ day corporate ...
(Date:5/24/2017)... ... ... Lowe is a sought after actor, and also serves as the host of the ... all aspects of life, and a new segment is being developed on podiatry, which ... is essential to people’s overall well-being, and if viewers have feet problems, they may ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... food ingredient solutions for the food and beverage industry offers Citri-Fi®, a natural ... statements during the purchasing decision process. As a result, labels need to deliver ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... (PVDF) based sleep diagnostics sensors, announced today it had completed the first phase ... a mix of domestic and rest of world (ROW) authorized dealers specializing in ...
(Date:5/23/2017)... ... May 23, 2017 , ... Axiad IDS , a leading provider of ... has named the company a “Top 25 Cybersecurity Companies 2017.” Axiad IDS ... organizations simply and proactively address potential cybersecurity threats before they happen. The ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... Mass., May 10, 2017 Hologic, Inc. (Nasdaq: ... results for the fiscal second quarter ended April 1, ... of $1.84 increased 666.7% compared to the prior year ... resulted in a significant gain, while non-GAAP diluted EPS ... 3.2%, or 3.8% in constant currency terms.  Excluding the ...
(Date:5/10/2017)... Radiology has become the number one diagnostic ... spiraled to the number one ranking as a result.  ... before as the most complete and reliable method for ... back pain an MRI may confirm a suspected herniated ... in entirely different treatment protocols.  In these circumstances, patients ...
(Date:5/9/2017)...  Demonstrating its commitment to representing research- based ... Pharmaceutical Research and Manufacturers of America (PhRMA) today ... now have to meet new research and development ... join PhRMA. "By putting in place ... clear message that being a member of PhRMA ...
Breaking Medicine Technology: