Navigation Links
H1N1 simulation modeling shows rapid vaccine rollout effective in reducing infection rates
Date:10/13/2009

OTTAWA, OCTOBER 13, 2009 Early action, especially rapid rollout of vaccines, is extremely effective in reducing the attack rate of the H1N1 influenza virus, according to a simulation model of a pandemic outbreak reported in a new study in CMAJ (Canadian Medical Association Journal) www.cmaj.ca.

The article presents a simulation model that projects how many people will be infected under different disease control strategies. The model simulated a pandemic outbreak based on demographic information from London, a mid-sized city in Ontario, Canada as well as epidemiologic influenza pandemic data. It looked at the impact of vaccination timing, school closures and antiviral drug treatment strategies as well as the effect of pre-existing immunity.

The authors simulated a large range of possible scenarios that may play out in reality, to determine whether any general conclusions could be drawn. The model captures how vaccination not only protects vaccinated individuals but can also help the healthcare system to cope by flattening the peak of the outbreak and delaying the peak. The model provides mathematical predictions for how and when that could happen.

The H1N1 pandemic has required decision-makers to set policy in the face of significant uncertainties, and simulation models can be used to help them decide on the best strategy to mitigate the spread of infection.

"The results of our pandemic influenza simulation model suggest that vaccination can have a disproportionately large impact on reducing the attack rate in a "fall wave," although delays can significantly erode its effectiveness," write Dr. Marija Zivkovic Gojovic and coauthors.

As well, the model predicts that school closures would be effective. However, the authors note there are important social costs of school closures that they did not examine in the analysis. The study did not attempt to predict influenza-related deaths, and did not assess vaccination strategies targeted to high risk groups or specific age groups, such as school age children.

The model was developed by researchers from the University of Toronto, the Ontario Agency for Health Protection and Promotion and the Research Institute of the Hospital for Sick Children in Toronto; and University of Guelph in Guelph, Ontario.


'/>"/>

Contact: Kim Barnhardt
kim.barnhardt@cmaj.ca
613-520-7116 x2224
Canadian Medical Association Journal
Source:Eurekalert

Related medicine news :

1. B-Line Medical(TM) and the Center for Medical Simulation Announce Partnership
2. Mayo Clinic Multidisciplinary Simulation Center Receives Distinction as an ACS-Accredited Education Institute
3. Running shipwreck simulations backwards helps identify dangerous waves
4. Medical Simulation Corporation Announces Partnership with Methodist DeBakey Heart Center in Houston
5. Medical Simulation Corporation Launches Sales Force Training Program
6. ANSYS and Network Analysis Team Up to Improve Thermal Simulation
7. Medical Simulation Corporation Announces Partnership With University of Pennsylvania Health System
8. Modeling Simulation Predicts Potential Negative Impact on U.S. Blood Supply if ESA Use Limited for Chemotherapy-Induced Anemia
9. Medical Simulation Corporation and the American Board of Internal Medicine Introduce New Simulation for Physician Assessment and Evaluation
10. Professional Products, Inc. Integrates Clinical Skills and Simulation Center at the Johns Hopkins Hospital
11. KISTI Selects ANSYS as a Key Supplier in Engineering Simulation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... SC (PRWEB) , ... March 24, 2017 , ... Digital ... is excited to announce the opening of a Greenville, South Carolina location. ... for digital progress in Greenville. , “We’ve been working with South Carolina clients for ...
(Date:3/24/2017)... Orion, MI (PRWEB) , ... March 24, 2017 ... ... insurance assistance, financial planning, and related services to families and business owners across ... initiative aimed at feeding regional families struggling with financial difficulties. , The Oxford/Orion ...
(Date:3/24/2017)... ... March 24, 2017 , ... On June 9, 2017, Cassie ... Litigation seminar in Chicago, Illinois. She will present on: , Filing Benefit ... under ERISA involve claims for long-term disability benefits. This session will address ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... Medical Reiki™ Master in Frederick, MD. Judy says, “I am passionate about sharing ... is often a very difficult and challenging time.” , A Certified Medical Reiki™ ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... “The Adventures ... loving, smart and silly dog who lives his life to the fullest, as God ... of published author Patti Holmgren, a mother and grandmother pursuing her passion for writing, ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , Mar 24, 2017 The Board of ... company,s Annual Report 2016 including the complete 2016 Annual Accounts ... available on Nordic Nanovector,s website in the section Investor Relations/Reports ... ... enquiries: Tone Kvåle, Chief Financial Officer Cell: +47-91-51-95-76 Email: ...
(Date:3/23/2017)... N.C. , March 23, 2017  Transportation Insight, ... as an end-to-end supply chain management firm with expertise ... Consumer Product Solutions Rick Zaffarano was named ... of the Supply Chain by the only publication exclusively ... global food supply chain. "Rick has brought ...
(Date:3/23/2017)... , March 23, 2017 ... and Healthcare disease pipeline guide Primary Hyperoxaluria - ... the Primary Hyperoxaluria (Genito Urinary System And Sex ... rare condition characterized by recurrent kidney and bladder ... substance called oxalate. Symptoms include blood in the ...
Breaking Medicine Technology: