Navigation Links
H1N1 simulation modeling shows rapid vaccine rollout effective in reducing infection rates
Date:10/13/2009

OTTAWA, OCTOBER 13, 2009 Early action, especially rapid rollout of vaccines, is extremely effective in reducing the attack rate of the H1N1 influenza virus, according to a simulation model of a pandemic outbreak reported in a new study in CMAJ (Canadian Medical Association Journal) www.cmaj.ca.

The article presents a simulation model that projects how many people will be infected under different disease control strategies. The model simulated a pandemic outbreak based on demographic information from London, a mid-sized city in Ontario, Canada as well as epidemiologic influenza pandemic data. It looked at the impact of vaccination timing, school closures and antiviral drug treatment strategies as well as the effect of pre-existing immunity.

The authors simulated a large range of possible scenarios that may play out in reality, to determine whether any general conclusions could be drawn. The model captures how vaccination not only protects vaccinated individuals but can also help the healthcare system to cope by flattening the peak of the outbreak and delaying the peak. The model provides mathematical predictions for how and when that could happen.

The H1N1 pandemic has required decision-makers to set policy in the face of significant uncertainties, and simulation models can be used to help them decide on the best strategy to mitigate the spread of infection.

"The results of our pandemic influenza simulation model suggest that vaccination can have a disproportionately large impact on reducing the attack rate in a "fall wave," although delays can significantly erode its effectiveness," write Dr. Marija Zivkovic Gojovic and coauthors.

As well, the model predicts that school closures would be effective. However, the authors note there are important social costs of school closures that they did not examine in the analysis. The study did not attempt to predict influenza-related deaths, and did not assess vaccination strategies targeted to high risk groups or specific age groups, such as school age children.

The model was developed by researchers from the University of Toronto, the Ontario Agency for Health Protection and Promotion and the Research Institute of the Hospital for Sick Children in Toronto; and University of Guelph in Guelph, Ontario.


'/>"/>

Contact: Kim Barnhardt
kim.barnhardt@cmaj.ca
613-520-7116 x2224
Canadian Medical Association Journal
Source:Eurekalert

Related medicine news :

1. B-Line Medical(TM) and the Center for Medical Simulation Announce Partnership
2. Mayo Clinic Multidisciplinary Simulation Center Receives Distinction as an ACS-Accredited Education Institute
3. Running shipwreck simulations backwards helps identify dangerous waves
4. Medical Simulation Corporation Announces Partnership with Methodist DeBakey Heart Center in Houston
5. Medical Simulation Corporation Launches Sales Force Training Program
6. ANSYS and Network Analysis Team Up to Improve Thermal Simulation
7. Medical Simulation Corporation Announces Partnership With University of Pennsylvania Health System
8. Modeling Simulation Predicts Potential Negative Impact on U.S. Blood Supply if ESA Use Limited for Chemotherapy-Induced Anemia
9. Medical Simulation Corporation and the American Board of Internal Medicine Introduce New Simulation for Physician Assessment and Evaluation
10. Professional Products, Inc. Integrates Clinical Skills and Simulation Center at the Johns Hopkins Hospital
11. KISTI Selects ANSYS as a Key Supplier in Engineering Simulation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... DC (PRWEB) , ... April 24, 2017 , ... The ... recognized during ATA 2017: Telehealth 2.0 — the American Telemedicine Association’s annual conference, on ... Santana Telehealth Project for using telemedicine to improve the lives of the poor and ...
(Date:4/24/2017)... ... April 24, 2017 , ... NEPC Director Kevin Welner has ... Research Award. The award honors scholars exemplary in their capacity to communicate important ... has demonstrated the capacity to deepen the public’s understanding and appreciation of the ...
(Date:4/24/2017)... ... 24, 2017 , ... The California Dental Association Foundation’s two-day volunteer dental clinic, ... people during the April 22-23 event at the San Mateo Event Center. , ... to care, CDA Cares educates the public and policymakers about the importance of good ...
(Date:4/24/2017)... Houston (PRWEB) , ... April 24, 2017 , ... The ... an innovative technology that allows anyone, anywhere to track their cognitive health, and share ... to check their own brain health on the museum's website. , BrainCheck founder, Dr. ...
(Date:4/24/2017)... ... April 24, 2017 , ... My T Chai, a ... products are now available for purchase on RevNutrition.com, a popular website specializing in sales ... produced and popularized in ancient India and Siam. It spread across Asia and Africa ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017 Research and Markets ... - Innovation Driven by Rapidly Expanding Injectables Market and Increasing Usage ... offering. ... drug delivery technologies will rise from USD 20 Billion in 2015 ... Global Drug Delivery Technologies - Innovation Driven by Rapidly Expanding Injectables ...
(Date:4/20/2017)... 2017  AbbVie (NYSE: ABBV), a global biopharmaceutical ... chronic hepatitis C virus (HCV) infected patients with ... compensated cirrhosis (Child-Pugh A) achieved sustained virologic response ... its investigational, pan-genotypic regimen of glecaprevir/pibrentasvir (G/P). These ... 12 weeks of G/P treatment without ribavirin. Patients ...
(Date:4/20/2017)... 20, 2017 NeuroVive Pharmaceutical AB (Nasdaq ... positive preclinical results demonstrating anti-fibrotic effects with ... steatohepatitis (NASH), in an additional well-validated experimental ... has previously shown similar anti-fibrotic effects in ... scientists present novel data demonstrating anti-fibrotic effects ...
Breaking Medicine Technology: