Navigation Links
Gut flora affects maturation of B cells in infants

Infants whose gut is colonised by E. coli bacteria early in life have a higher number of memory B cells in their blood, reveals a study of infants carried out at the Sahlgrenska Academy at the University of Gothenburg, Sweden.

The bacteria in our gut outnumber the cells in our bodies by a factor of ten and are extremely important for our health because they stimulate the maturation of the immune system. The normal bacterial flora in the gut is established at the very beginning of our lives, but an increasingly hygienic lifestyle has led to changes in this flora.

Colonised ever later

These days Swedish children are colonised by E. coli bacteria later and later. They also have a less varied bacterial flora and a smaller turnover of bacterial strains in the gut than children in developing countries. Meanwhile, diseases caused by deficiencies in immune regulation have increased sharply, making allergies a major public health issue in the Western World.

B cells play key role in development of allergies

Researchers at the University of Gothenburg's Sahlgrenska Academy have looked at B cells, a type of white blood cell that produces antibodies that can protect the body against infection and play a key role in the development of allergies. By studying 65 healthy newborn babies in the Vstra Gtaland region, researcher Anna-Carin Lundell and her colleagues were able to show that infants whose gut is colonised by E. coli bacteria during the first few weeks of life had a higher number of memory B cells at the age of both four and 18 months.

"The results are important for understanding the relationship between our complex bacterial gut flora and our immune system, and show what we risk losing with an excessively hygienic lifestyle," Anna-Carin Lundell explains.

"Most of the bacteria around us are harmless, and we should see them as a very important form of training so that our children's immune systems mature properly. Healthy newborns should not be over-protected against natural exposure of the gut flora."

Contact: Anna-Carin Lundell
University of Gothenburg

Related medicine news :

1. Healthy gut flora could prevent obesity
2. 20 Years of Good Digestion: Flora Source by Nutri-Health Reaches a Probiotic Milestone
3. FemFlora Reformulated with New Complex of Probiotic Bacteria
4. Joslin scientists identify important mechanism that affects the aging process
5. KRAS gene mutation and amplification status affects sensitivity to antifolate therapy
6. Secondhand Smoke Affects Young Girls More Than Boys: Study
7. Autism affects motor skills, study indicates
8. Mayo Clinic finds mild cognitive impairment is common, affects men most
9. Little Known About How Autism Affects Teen Drivers: Researchers
10. Mothers weight before and during pregnancy affects babys weight
11. Hypertension affects brain capacity
Post Your Comments:
Related Image:
Gut flora affects maturation of B cells in infants
(Date:12/1/2015)... , ... December 01, 2015 , ... Lutronic, a leading ... Clarity, the latest addition to the devices for sale in the United States. ... Alexandrite and long-pulsed 1064 nm Nd:YAG lasers, into a single platform that is easy ...
(Date:12/1/2015)... ... 01, 2015 , ... PYA’s latest white paper, “ PYA ... main “pain point” for merging or aligning healthcare provider organizations—when mergers and other ... This quick-read guidance suggests that failing to recognize the power of an ...
(Date:12/1/2015)... ... December 01, 2015 , ... PartnerTech , ... membership and leadership since 2008. Gary Bruce, President of PartnerTech North America, currently ... spent a significant amount of time in Sweden since joining PartnerTech based in ...
(Date:12/1/2015)... ... December 01, 2015 , ... Nurotron Biotechnology Co., Ltd., maker ... order to date. , The order will be from the China Disabled Persons’ ... Implant System is an effective solution for children and adults suffering from severe ...
(Date:12/1/2015)... Charlotte, NC (PRWEB) , ... December 01, 2015 ... ... NHS Foundation Trust on receiving the 2015 HSJ Acute Sector Innovation Award on ... of improving the patient care experience, and propose exciting enhancements to the medical ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... BOSTON , Dec. 1, 2015  The ... (HCOs) to develop shared care plans that help ... These care plans will be digitally enabled, incorporate ... unique needs and desires. They will also allow ... a patient,s health journey is optimal. That is ...
(Date:12/1/2015)... Germany , December 1, 2015 /PRNewswire/ ... leading global manufacturer of eye and gaze tracking solutions, ... SMI remote eye trackers as a component of its ... concussions, eye sight, and medical and performance issues in ... part of SMI,s mass-market-ready eye tracking platform, which is ...
(Date:12/1/2015)... THE WOODLANDS, Texas , Dec. 1, ... LXRX )  announced today that top-line data ... results of telotristat etiprate in treating carcinoid ... tumors consistent with the clinical benefit observed ... study was designed as a companion to ...
Breaking Medicine Technology: