Navigation Links
Gut flora affects maturation of B cells in infants
Date:5/7/2012

Infants whose gut is colonised by E. coli bacteria early in life have a higher number of memory B cells in their blood, reveals a study of infants carried out at the Sahlgrenska Academy at the University of Gothenburg, Sweden.

The bacteria in our gut outnumber the cells in our bodies by a factor of ten and are extremely important for our health because they stimulate the maturation of the immune system. The normal bacterial flora in the gut is established at the very beginning of our lives, but an increasingly hygienic lifestyle has led to changes in this flora.

Colonised ever later

These days Swedish children are colonised by E. coli bacteria later and later. They also have a less varied bacterial flora and a smaller turnover of bacterial strains in the gut than children in developing countries. Meanwhile, diseases caused by deficiencies in immune regulation have increased sharply, making allergies a major public health issue in the Western World.

B cells play key role in development of allergies

Researchers at the University of Gothenburg's Sahlgrenska Academy have looked at B cells, a type of white blood cell that produces antibodies that can protect the body against infection and play a key role in the development of allergies. By studying 65 healthy newborn babies in the Vstra Gtaland region, researcher Anna-Carin Lundell and her colleagues were able to show that infants whose gut is colonised by E. coli bacteria during the first few weeks of life had a higher number of memory B cells at the age of both four and 18 months.

"The results are important for understanding the relationship between our complex bacterial gut flora and our immune system, and show what we risk losing with an excessively hygienic lifestyle," Anna-Carin Lundell explains.

"Most of the bacteria around us are harmless, and we should see them as a very important form of training so that our children's immune systems mature properly. Healthy newborns should not be over-protected against natural exposure of the gut flora."


'/>"/>
Contact: Anna-Carin Lundell
anna-carin.lundell@rheuma.gu.se
46-031-342-6411
University of Gothenburg
Source:Eurekalert  

Related medicine news :

1. Healthy gut flora could prevent obesity
2. 20 Years of Good Digestion: Flora Source by Nutri-Health Reaches a Probiotic Milestone
3. FemFlora Reformulated with New Complex of Probiotic Bacteria
4. Joslin scientists identify important mechanism that affects the aging process
5. KRAS gene mutation and amplification status affects sensitivity to antifolate therapy
6. Secondhand Smoke Affects Young Girls More Than Boys: Study
7. Autism affects motor skills, study indicates
8. Mayo Clinic finds mild cognitive impairment is common, affects men most
9. Little Known About How Autism Affects Teen Drivers: Researchers
10. Mothers weight before and during pregnancy affects babys weight
11. Hypertension affects brain capacity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gut flora affects maturation of B cells in infants
(Date:10/13/2017)... ... ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to host ... items from across the nation, this holiday-themed event will raise funds and awareness for ... The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 p.m.) ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, ... lowdown on sciatica in a new episode of "Success Files," which is an ... and innovation and investigates each subject in-depth with passion and integrity. , Sciatica ...
(Date:10/12/2017)... WILMINGTON, Del. (PRWEB) , ... October 12, 2017 ... ... technology and advisory services for healthcare compliance program management, will showcase a range ... and National Association for Assisted Living (NCAL) Convention and Expo to be held ...
(Date:10/12/2017)... CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... cold therapy products, announced today the introduction of an innovative new design of the ... multipurpose pad so you get maximum comfort while controlling your pain while using cold ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... Mohebi Hair Restoration, has recently contributed a medical article to the newly revamped ... cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as Follicular ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2, 2017 Halo Labs announces the European launch of ... the HORIZON at MIBio 2017 in Cambridge, U.K ... particulate matter in biopharmaceutical samples with unprecedented speed and sensitivity while ... technique Backgrounded Membrane Imaging. ... HORIZON subvisible particle analysis system ...
(Date:9/27/2017)... 27, 2017  Commended for their devotion to personalized service, ... as number one in the South Florida Business Journal,s 50 ... 5000 yearly list, the national specialty pharmacy has found its ... will soon be honored by SFBJ as the 2017 ... Set to receive his award in October, Bardisa said ...
(Date:9/23/2017)... 22, 2017 Janssen Biotech, Inc. (Janssen) announced ... from the U.S. Food and Drug Administration (FDA) for ... for the treatment of moderately to severely active rheumatoid ... data are needed to further evaluate the safety of ... RA. "We ...
Breaking Medicine Technology: