Navigation Links
Gum Disease, HPV a Double Whammy
Date:4/4/2008

The two work in tandem to increase risk of tongue cancer, study shows

FRIDAY, April 4 (HealthDay News) -- Your risk of developing tongue cancer increases if you have severe gum disease along with human papillomavirus (HPV), new research suggests.

Previous studies have found periodontitis, which destroys connective tissue and bone supporting the teeth, and HPV each pose increased risks of cancer in the head, neck or tongue. This new study, from researchers at the University at Buffalo School of Dental Medicine, shows the two may work in tandem.

In a study of 30 patients newly diagnosed with squamous cell carcinoma on the base of the tongue, 63 percent (19 patients) had tumors testing positive for a common type of HPV. In addition, 90 percent of the patients with HPV-positive tumors had periodontitis, and 79 percent of patients whose tumors showed no presence of HPV did not have periodontitis.

"Evidence of periodontitis-HPV synergy has important practical implications, because there is a safe treatment for periodontitis but no treatment for HPV infection," Mine Tezal, an assistant professor in the dental school's Department of Oral Diagnostic Sciences, said in a prepared statement. "If these results are confirmed by other studies, this has a tremendous relevance in predicting and intervening in the initiation and prognosis of HPV-related diseases, including head and neck cancers."

Tezal, who is also a research scientist at Roswell Park Cancer Institute, is scheduled to present the finding Friday at the American Association of Dental Research annual meeting, in Dallas.

Most people contract HPV infection at least once in their lives, but one's immune system often fights it off without incident.

"Persistence of HPV infection is the strongest risk factor for carcinogenesis," Tezal said. "Thus, the identification of factors that influence the persistence of HPV infection is critical to facilitate efforts to prevent head and neck cancers. This study implicates that chronic inflammation and co-infection with oral bacteria may be significant factors in the natural history of HPV infection."

More information

The U.S. National Library of Medicine has more about oral cancer.



-- Kevin McKeever



SOURCE: University at Buffalo, news release, April 4, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Large Disparities in Kidney Testing Based on Disease, Gender and State, Quest Diagnostics Health Trends(TM) Report Finds
2. U.S. Deaths Down From Heart Disease, Stroke
3. New studies on cancer and schizophrenia, depression and heart disease, trauma and autism
4. Children with sickle cell disease, silent strokes show some relief with blood transfusions
5. Researchers Spot Link Between Heart Disease, Income
6. To fight disease, animals, like plants, can tolerate parasites
7. People with Schizophrenia More Likely to Die of Heart Disease, Reports the Harvard Mental Health Letter
8. Study Links Coronary Disease, Colon Cancer
9. Environmental stress probed in cardiovascular disease, diabetes
10. Renal function and heart disease, and more
11. Uroplasty Plans to Double Sales Force During Fiscal 2009
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gum Disease, HPV a Double Whammy 
(Date:4/29/2016)... Beverly Hills, CA (PRWEB) , ... April 29, 2016 , ... ... distributor of devices and products for the head and neck/ear, nose and throat specialty, ... Safety Device , The KOTLER NASAL AIRWAY™ is a newly patented safety ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... a growth round of funding led by Eastside Partners, with participation from existing ... rapidly growing customer base and accelerate its technology and product roadmap. ...
(Date:4/29/2016)... ... April 29, 2016 , ... Regenerative Medicine Solutions (RMS) scored ... satisfaction survey, earning them second place for Tampa’s Best Places to Work. They were ... “This is a great accomplishment for our team,” says RMS Human Resources Manager Irene ...
(Date:4/29/2016)... CA (PRWEB) , ... April 29, 2016 , ... The ... L. Frederick, Dr. Sanaz Ghazal, and Dr. Daniel A. Potter -- are proud of ... for Assisted Reproductive Technology (SART). In April, SART published the latest verified ...
(Date:4/29/2016)... ... April 29, 2016 , ... Natren, Inc. recently sent representatives ... Petbiotics ™, as they fondly call them. As animal lovers, they were ... their non-profit organizations. Animal rescues across the nation face huge hurdles rescuing animals ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... , April 29, 2016 ... glyco-biology expertise, today announces the appointment of Dr. ... Dr. Zurlo is an oncologist with many years clinical ... and biotechnology industries. His last role was at Mologen ... of the Executive Board. Previously Dr. Zurlo held various ...
(Date:4/28/2016)... YORK , April 28, 2016  While ... notably complement the company,s valve repair and stent ... move also places Abbott more firmly into patient ... of the fastest growing device areas, with double-digit ... its recent report,  Advanced Remote Patient Monitoring ...
(Date:4/28/2016)... Dr. ... und Stephen Schmidt werden Teil ... ein führender Anbieter cloudbasierter Softwarelösungen für den ... neue Führungskräfte zum Team Sicherheit und Pharmakovigilanz ... Erfahrungen mitbringen.  Dies wird die Geschäftseinheit Sicherheit ...
Breaking Medicine Technology: