Navigation Links
Gum Disease, HPV a Double Whammy
Date:4/4/2008

The two work in tandem to increase risk of tongue cancer, study shows

FRIDAY, April 4 (HealthDay News) -- Your risk of developing tongue cancer increases if you have severe gum disease along with human papillomavirus (HPV), new research suggests.

Previous studies have found periodontitis, which destroys connective tissue and bone supporting the teeth, and HPV each pose increased risks of cancer in the head, neck or tongue. This new study, from researchers at the University at Buffalo School of Dental Medicine, shows the two may work in tandem.

In a study of 30 patients newly diagnosed with squamous cell carcinoma on the base of the tongue, 63 percent (19 patients) had tumors testing positive for a common type of HPV. In addition, 90 percent of the patients with HPV-positive tumors had periodontitis, and 79 percent of patients whose tumors showed no presence of HPV did not have periodontitis.

"Evidence of periodontitis-HPV synergy has important practical implications, because there is a safe treatment for periodontitis but no treatment for HPV infection," Mine Tezal, an assistant professor in the dental school's Department of Oral Diagnostic Sciences, said in a prepared statement. "If these results are confirmed by other studies, this has a tremendous relevance in predicting and intervening in the initiation and prognosis of HPV-related diseases, including head and neck cancers."

Tezal, who is also a research scientist at Roswell Park Cancer Institute, is scheduled to present the finding Friday at the American Association of Dental Research annual meeting, in Dallas.

Most people contract HPV infection at least once in their lives, but one's immune system often fights it off without incident.

"Persistence of HPV infection is the strongest risk factor for carcinogenesis," Tezal said. "Thus, the identification of factors that influence the persistence of HPV infection is critical to facilitate efforts to prevent head and neck cancers. This study implicates that chronic inflammation and co-infection with oral bacteria may be significant factors in the natural history of HPV infection."

More information

The U.S. National Library of Medicine has more about oral cancer.



-- Kevin McKeever



SOURCE: University at Buffalo, news release, April 4, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Large Disparities in Kidney Testing Based on Disease, Gender and State, Quest Diagnostics Health Trends(TM) Report Finds
2. U.S. Deaths Down From Heart Disease, Stroke
3. New studies on cancer and schizophrenia, depression and heart disease, trauma and autism
4. Children with sickle cell disease, silent strokes show some relief with blood transfusions
5. Researchers Spot Link Between Heart Disease, Income
6. To fight disease, animals, like plants, can tolerate parasites
7. People with Schizophrenia More Likely to Die of Heart Disease, Reports the Harvard Mental Health Letter
8. Study Links Coronary Disease, Colon Cancer
9. Environmental stress probed in cardiovascular disease, diabetes
10. Renal function and heart disease, and more
11. Uroplasty Plans to Double Sales Force During Fiscal 2009
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gum Disease, HPV a Double Whammy 
(Date:12/8/2016)... ... December 08, 2016 , ... The Compretta Insurance Agency, a family ... in and around the Hancock County area, is announcing the launch of a charity ... , The Hancock County Food Pantry has worked for more than 30 years to ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... to families and business owners in and around central Kansas, is joining the ... at-risk youth in the region. , Headquartered in Wichita, Youth Horizons works to ...
(Date:12/7/2016)... ... , ... Students attending Envision’s summer 2017 National Youth ... experience in an emergency medical simulation, When Care is Hours Away. This dynamic ... skills that are critical success in a future career and beyond. , The ...
(Date:12/7/2016)... ... December 07, 2016 , ... Kenall Manufacturing, a leader in sealed healthcare ... The MPCNGX is a multi-function, sealed, LED luminaire that meets the needs of everyone ... when it’s needed. , A 2’ x 4’ model features four modes: ...
(Date:12/7/2016)... ... December 07, 2016 , ... Silhouette Instalift is a simple, ... and tightening the skin of the face to create more youthful features. While ... very little downtime, Silhouette Instalift is a novel, minimally invasive facial procedure that ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... MOINES, Iowa , Dec. 8, 2016 /PRNewswire/ ... a pharmaceutical company advancing technologies designed to address ... appointment of Chitra Edwin , Ph.D., RAC, ... Compliance. Dr. Edwin will provide leadership for all ... for regulatory approvals, preparation of regulatory submissions, serving ...
(Date:12/7/2016)... , Dec. 7, 2016  Urinary catheters are ... retention and other urological disorders. Urinary catheters include ... (condom) catheter. Indwelling or Foley catheter is a ... type of catheter is inserted into the bladder ... A tiny balloon attachment at one end of ...
(Date:12/7/2016)... 2016  Palatin Technologies, Inc. ("Palatin") (NYSE MKT: ... previously disclosed underwritten public offering of units with ... sole book-running manager, Roth Capital Partners acted as ... co-manager for the offering. "This financing ... proceeds, allowing us to continue advancing bremelanotide for ...
Breaking Medicine Technology: