Navigation Links
Gum Disease, HPV a Double Whammy
Date:4/4/2008

The two work in tandem to increase risk of tongue cancer, study shows

FRIDAY, April 4 (HealthDay News) -- Your risk of developing tongue cancer increases if you have severe gum disease along with human papillomavirus (HPV), new research suggests.

Previous studies have found periodontitis, which destroys connective tissue and bone supporting the teeth, and HPV each pose increased risks of cancer in the head, neck or tongue. This new study, from researchers at the University at Buffalo School of Dental Medicine, shows the two may work in tandem.

In a study of 30 patients newly diagnosed with squamous cell carcinoma on the base of the tongue, 63 percent (19 patients) had tumors testing positive for a common type of HPV. In addition, 90 percent of the patients with HPV-positive tumors had periodontitis, and 79 percent of patients whose tumors showed no presence of HPV did not have periodontitis.

"Evidence of periodontitis-HPV synergy has important practical implications, because there is a safe treatment for periodontitis but no treatment for HPV infection," Mine Tezal, an assistant professor in the dental school's Department of Oral Diagnostic Sciences, said in a prepared statement. "If these results are confirmed by other studies, this has a tremendous relevance in predicting and intervening in the initiation and prognosis of HPV-related diseases, including head and neck cancers."

Tezal, who is also a research scientist at Roswell Park Cancer Institute, is scheduled to present the finding Friday at the American Association of Dental Research annual meeting, in Dallas.

Most people contract HPV infection at least once in their lives, but one's immune system often fights it off without incident.

"Persistence of HPV infection is the strongest risk factor for carcinogenesis," Tezal said. "Thus, the identification of factors that influence the persistence of HPV infection is critical to facilitate efforts to prevent head and neck cancers. This study implicates that chronic inflammation and co-infection with oral bacteria may be significant factors in the natural history of HPV infection."

More information

The U.S. National Library of Medicine has more about oral cancer.



-- Kevin McKeever



SOURCE: University at Buffalo, news release, April 4, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Large Disparities in Kidney Testing Based on Disease, Gender and State, Quest Diagnostics Health Trends(TM) Report Finds
2. U.S. Deaths Down From Heart Disease, Stroke
3. New studies on cancer and schizophrenia, depression and heart disease, trauma and autism
4. Children with sickle cell disease, silent strokes show some relief with blood transfusions
5. Researchers Spot Link Between Heart Disease, Income
6. To fight disease, animals, like plants, can tolerate parasites
7. People with Schizophrenia More Likely to Die of Heart Disease, Reports the Harvard Mental Health Letter
8. Study Links Coronary Disease, Colon Cancer
9. Environmental stress probed in cardiovascular disease, diabetes
10. Renal function and heart disease, and more
11. Uroplasty Plans to Double Sales Force During Fiscal 2009
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gum Disease, HPV a Double Whammy 
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media with ... X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color ... users can now reveal the media of their split screens with growing colorful ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... patient payment industry today announced its strategic partnership with Connance, a healthcare ... , The two companies’ proven, proprietary technology combine to provide health systems, ...
(Date:6/27/2016)... Park, KS (PRWEB) , ... June 27, 2016 , ... ... in retailers of Eyeglasses . , Millions of individuals in the United States ... eyeglasses have become a way to both correct vision and make a fashion statement. ...
(Date:6/26/2016)... Battle Creek, Michigan (PRWEB) , ... June 26, 2016 , ... ... abuse, joined as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table ... held in honor of the city’s history as home to some of the world’s ...
(Date:6/26/2016)... ... ... PawPaws brand pet supplements owned by Whole Health Supply is ... of felines. The formula is all-natural and is made from Chinese herbs that have ... Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root Extract ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... appointment of Dr. Edward Futcher to ... Director, effective June 23, 2016.Dr. Futcher was also ... and Governance Committees.  As a non-executive member of ... expertise and strategic counsel to VolitionRx in connection ...
(Date:6/23/2016)... June 23, 2016 Research and ... Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), ... Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is projected ... CAGR of 6.1% in the forecast period 2016 to ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
Breaking Medicine Technology: