Navigation Links
Guillermina 'Gigi' Lozano, Ph.D., awarded AACR Charlotte Friend Memorial Lectureship
Date:4/8/2013

HOUSTON Guillermina "Gigi" Lozano, Ph.D., chair and professor in the Department of Genetics at The University of Texas MD Anderson Cancer Center, is the recipient of the 16th annual Women in Cancer Research Charlotte Friend Memorial Lectureship awarded by The American Association for Cancer Research (AACR), recognizing her contributions to the field of cancer research and the advancement of women in science.

A pioneer in understanding the p53 tumor suppressor pathway, Lozano will deliver her award lecture, "Activities of Mutant p53 Proteins in Cancer," today as part of the 2013 AACR Annual Meeting in Washington, D.C., April 6 10. Her award is one of six for MD Anderson faculty this year.

Lozano's lab at MD Anderson was the first to establish p53 as a transcriptional activator of other genes. Their landmark study published in Science in 1989 identified a p53 transactivation domain and showed that p53 mutants failed to activate transcription, paving the way for important discoveries regarding its mechanism in the development of numerous cancers including breast, colon, lung and ovarian cancer.

Her subsequent research provided the necessary mouse models to validate the critical gatekeeper role the protein Mdm2 plays in regulating p53 activity, as well as establishing the importance of dual functions of p53 in preventing tumor development where it not only forces cell death, but also halts a defective cell's ability to reproduce and helps maintain genomic stability. Most recently she has explored how mutant p53 proteins contribute to cancer development and treatment outcomes.

"It is an incredible honor to be in the same company as Dr. Friend, a researcher who has inspired future generations of female scientists looking to excel in their research," said Lozano. "What drives me is the hope that someday my research will translate into novel therapies targeting p53, ultimately impacting clinical care and saving the lives of patients affected by cancer."

Lozano celebrates her 25th anniversary at MD Anderson this year. Over the course of her career, she has published 179 peer-reviewed articles in prestigious scientific journals, reviews and book chapters . She has devoted extensive efforts to teaching young scientists, an aspect of her work that she finds exceptionally rewarding.

"Not only do I love teaching and helping those who want to learn, but I also enjoy the two-way learning that takes place between the generations and the insights that occur as both aim to push the progress of cancer research," Lozano said. Twenty-five graduate students have received M.S. and Ph.D. degrees under her direction and she has trained 34 postdoctoral students and fellows in her lab.

She credits the mentorship of Arnold Levine, Ph.D., her postgraduate advisor at Princeton University and the discoverer of p53, and Peter Mueller of the Max Planck Institute for their guidance early in and throughout her career. "Their invaluable perspective has driven me to reach for goals I might never have dreamed of," Lozano said. She also is thankful for the support of her husband and daughter noting, "They keep me from doing too much at once."

Her research program has been supported by continuous funding from the National Cancer Institute. Other honors include the Sixth Annual AACR-Minorities in Cancer Research Jane Cooke Wright Lectureship and a position on the Scientific Advisory Committee for Stand Up To Cancer (SU2C). She was elected a fellow of the American Association for the Advancement of Science in 2011. Lozano is a distinguished alumnus of both University of Medicine & Dentistry of New Jersey Graduate School of Biomedical Sciences and The University of Texas Pan American. Lozano received her Ph.D. from Rutgers University and completed post-graduate work at Princeton University.


'/>"/>

Contact: Scott Merville
smerville@mdanderson.org
713-516-4855
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

Related medicine news :

1. UMMS researcher Victor Ambros, Ph.D., named co-recipient of 2012 Janssen Award for Biomedical Research
2. ASH honors Margaret A. Goodell, Ph.D., with 2012 William Dameshek Prize
3. John DeLuca, Ph.D., of Kessler Foundation delivers keynote at IPMSC meeting in Milan
4. Joslins Susan Bonner-Weir, Ph.D., named American Association for the Advancement of Science Fellow
5. Nobel laureate Roger Tsien, Ph.D., keynotes Cedars-Sinai nanomedicine conference March 15, 16
6. BIDMCs Mark Andermann, Ph.D., receives Smith Family Foundation Biomedical Research Award
7. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
8. $9 million grant awarded to UH to study, treat learning disabilities
9. Kessler Foundation scientist awarded $554,000 for multiple sclerosis employment research
10. Moffitt researcher awarded GE grant to develop tool to detect breast cancer metastasis genetic risks
11. Grant awarded to help improve problem-solving skills for deaf and hard-of-hearing students
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... , ... “Vintage and Harvest A Cultivation of Christian Love” is the creation ... North Carolina with his wife, Anna Marie. He and his wife are the proud ... also the author of “Shadow and Substance.” , “Love, the agape kind, is seen ...
(Date:3/23/2017)... ... 2017 , ... In 2016 the World Health Organization declared the Zika virus ... Zika-related cases in the Americas within the next year. Lyme disease is one of ... skyrocketing to an estimated 329,000. Yet, Zika, Lyme and other insect borne illnesses are ...
(Date:3/23/2017)... ... March 23, 2017 , ... Demonstrating ... communities, 16 more public health departments have been awarded national accreditation through the ... million people into the expanding network of communities across the nation whose health ...
(Date:3/23/2017)... ... March 23, 2017 , ... The IoT (Internet of Things) is ... making a huge impact on businesses and individual consumers alike. Laboratories can maximize ... have a value anywhere from $4 trillion to $11 trillion dollars by the year ...
(Date:3/23/2017)... , ... March 23, 2017 ... ... financial services firm serving the families and businesses of the Norwalk and ... program. Northern Ohio Recovery Center (N.O.R.A.) is a nonprofit, community-based substance abuse ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... March 24, 2017 ShangPharma, a ... and cost-effective drug development and discovery services, ... biotechnology industry, announced today the intent for ... will be consolidating the Contract Research Organizations ... Shanghai ChemPartner. These entities include ChemPartner Shanghai, ...
(Date:3/24/2017)... India , March 24, 2017 A ... market has been growing rapidly as the global sales of Adcetris ... the growth in the antibody drug conjugates market is driven by ... of cancer and wider therapeutic window offered by ADCs. ... Browse 3 Tables and 94 ...
(Date:3/24/2017)... , March 24, 2017  Eli Lilly and ... plans to invest $850 million in its U.S. ... across its U.S. enterprise, including research laboratories, manufacturing ... are being driven by demand for Lilly products, ... medicines in development targeting cancer, pain, diabetes and ...
Breaking Medicine Technology: