Navigation Links
Guillermina 'Gigi' Lozano, Ph.D., awarded AACR Charlotte Friend Memorial Lectureship

HOUSTON Guillermina "Gigi" Lozano, Ph.D., chair and professor in the Department of Genetics at The University of Texas MD Anderson Cancer Center, is the recipient of the 16th annual Women in Cancer Research Charlotte Friend Memorial Lectureship awarded by The American Association for Cancer Research (AACR), recognizing her contributions to the field of cancer research and the advancement of women in science.

A pioneer in understanding the p53 tumor suppressor pathway, Lozano will deliver her award lecture, "Activities of Mutant p53 Proteins in Cancer," today as part of the 2013 AACR Annual Meeting in Washington, D.C., April 6 10. Her award is one of six for MD Anderson faculty this year.

Lozano's lab at MD Anderson was the first to establish p53 as a transcriptional activator of other genes. Their landmark study published in Science in 1989 identified a p53 transactivation domain and showed that p53 mutants failed to activate transcription, paving the way for important discoveries regarding its mechanism in the development of numerous cancers including breast, colon, lung and ovarian cancer.

Her subsequent research provided the necessary mouse models to validate the critical gatekeeper role the protein Mdm2 plays in regulating p53 activity, as well as establishing the importance of dual functions of p53 in preventing tumor development where it not only forces cell death, but also halts a defective cell's ability to reproduce and helps maintain genomic stability. Most recently she has explored how mutant p53 proteins contribute to cancer development and treatment outcomes.

"It is an incredible honor to be in the same company as Dr. Friend, a researcher who has inspired future generations of female scientists looking to excel in their research," said Lozano. "What drives me is the hope that someday my research will translate into novel therapies targeting p53, ultimately impacting clinical care and saving the lives of patients affected by cancer."

Lozano celebrates her 25th anniversary at MD Anderson this year. Over the course of her career, she has published 179 peer-reviewed articles in prestigious scientific journals, reviews and book chapters . She has devoted extensive efforts to teaching young scientists, an aspect of her work that she finds exceptionally rewarding.

"Not only do I love teaching and helping those who want to learn, but I also enjoy the two-way learning that takes place between the generations and the insights that occur as both aim to push the progress of cancer research," Lozano said. Twenty-five graduate students have received M.S. and Ph.D. degrees under her direction and she has trained 34 postdoctoral students and fellows in her lab.

She credits the mentorship of Arnold Levine, Ph.D., her postgraduate advisor at Princeton University and the discoverer of p53, and Peter Mueller of the Max Planck Institute for their guidance early in and throughout her career. "Their invaluable perspective has driven me to reach for goals I might never have dreamed of," Lozano said. She also is thankful for the support of her husband and daughter noting, "They keep me from doing too much at once."

Her research program has been supported by continuous funding from the National Cancer Institute. Other honors include the Sixth Annual AACR-Minorities in Cancer Research Jane Cooke Wright Lectureship and a position on the Scientific Advisory Committee for Stand Up To Cancer (SU2C). She was elected a fellow of the American Association for the Advancement of Science in 2011. Lozano is a distinguished alumnus of both University of Medicine & Dentistry of New Jersey Graduate School of Biomedical Sciences and The University of Texas Pan American. Lozano received her Ph.D. from Rutgers University and completed post-graduate work at Princeton University.


Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center

Related medicine news :

1. UMMS researcher Victor Ambros, Ph.D., named co-recipient of 2012 Janssen Award for Biomedical Research
2. ASH honors Margaret A. Goodell, Ph.D., with 2012 William Dameshek Prize
3. John DeLuca, Ph.D., of Kessler Foundation delivers keynote at IPMSC meeting in Milan
4. Joslins Susan Bonner-Weir, Ph.D., named American Association for the Advancement of Science Fellow
5. Nobel laureate Roger Tsien, Ph.D., keynotes Cedars-Sinai nanomedicine conference March 15, 16
6. BIDMCs Mark Andermann, Ph.D., receives Smith Family Foundation Biomedical Research Award
7. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
8. $9 million grant awarded to UH to study, treat learning disabilities
9. Kessler Foundation scientist awarded $554,000 for multiple sclerosis employment research
10. Moffitt researcher awarded GE grant to develop tool to detect breast cancer metastasis genetic risks
11. Grant awarded to help improve problem-solving skills for deaf and hard-of-hearing students
Post Your Comments:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance ... and the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, ... Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood cells, ...
(Date:6/24/2016)... ... 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited to ... Recovery® program to drive cancer patients to and from their cancer treatments. Comfort ... quality of life and ongoing independence. Getting to and from medical treatments is ...
(Date:6/24/2016)... Vegas, Nevada (PRWEB) , ... June 24, 2016 ... ... Las Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and processing ... Grove, in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Revolutionary technology ... Oticon , industry leaders in advanced audiology and ... Oticon Opn ™, the world,s first internet connected ... for IoT devices.      (Photo: ... a number of ,world firsts,: , TwinLink™ ...
(Date:6/23/2016)... MEDIA, Pa. , June 23, 2016 ... treatments in an outpatient dialysis facility.  Treatments are usually ... to 6 hours per visit, including travel time, equipment ... on a patient, but especially grueling for patients who ... residents of a skilled nursing and rehabilitation centers for ...
(Date:6/23/2016)... FRANKLIN, Tenn. , June 23, 2016 ... for automating, integrating and transforming the patient ... launch of several innovative new products and ... depth of its revenue cycle offerings. These ... establish more efficient workflows, remain compliant in ...
Breaking Medicine Technology: