Navigation Links
Guidelines can predict early menopause in child cancer survivors
Date:8/15/2014

Girls with cancer who are most likely to become infertile after treatment can be identified using guidelines developed almost 20 years ago, new research shows.

The criteria developed in Edinburgh will help to select which girls should be offered the opportunity to freeze some tissue from their ovaries for use in the future.

Doctors are optimistic that the frozen tissue could one day help young cancer survivors to have children of their own.

Some cancer treatments can affect female fertility by bringing on early menopause. Freezing samples of ovary tissue before patients start treatment is the only option to try to preserve their fertility.

At least 30 babies have been born from frozen ovarian tissue taken from adult women but the procedure remains unproven in girls and young women.

Taking the initial samples of ovaries to be frozen involves a surgical technique and is still relatively experimental. It is therefore crucial that doctors can accurately predict which patients are most likely to benefit and when it can be safely performed.

Guidelines were developed almost 20 years ago to select which girls should be offered the procedure, based on their age, type of cancer treatment and their chances of being cured of their cancer. Now that the girls are older, doctors are able to validate their predictions.

Researchers led by the University of Edinburgh validated the criteria by looking back at more than 400 girls with cancer who were under 18 years of age when diagnosed. They found that the criteria accurately predicted all but one of the patients who entered early menopause.

The study, funded by the Medical Research Council, is published today in the journal Lancet Oncology.

The lead researcher is Professor Hamish Wallace of the University of Edinburgh's Department of Child Life and Health and Consultant Paediatric Oncologist at the Royal Hospital for Sick Children (RHSC), where the research was carried out. He said: "Advances in lifesaving treatments mean that more and more young people with cancer are surviving the disease. Here we have an opportunity to help young women to have families of their own when they grow up, if they so choose."


'/>"/>
Contact: Jen Middleton
jen.middleton@ed.ac.uk
44-131-650-6514
University of Edinburgh
Source:Eurekalert

Related medicine news :

1. Experts Issue Guidelines for Treating Irritable Bowel Syndrome
2. Colorado Braces Itself for New Medical Marijuana Guidelines and Regulations
3. Drexel University College of Medicine Research May Lead to Improved Alzheimer’s/Vascular Dementia Diagnostic Guidelines
4. Baby aspirin? Many doctors dont recommend, despite guidelines
5. Portable Monitors OK for Spotting Sleep Apnea: New Guidelines
6. LymeDisease.org Endorses New Evidence-Based Lyme Guidelines: ILADS Guidelines Allow Patients to Understand Treatment Options and Make Informed Choices
7. 2014 ESC/ESA Guidelines on non-cardiac surgery: Cardiovascular assessment and management
8. New guidelines help keep asthma out of yellow zone
9. Study: Pediatric preventive care guidelines need retooling for computerized format
10. CarePoint Health – Bayonne Medical Center Joins Get With The Guidelines–Stroke Program
11. Breast cancer: DMP is largely consistent with guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... , ... December 08, 2016 , ... Vida ... an $18M Series B led by Canvas Ventures . Other investors include Nokia ... scale its mobile platform to serve more consumers who are managing chronic conditions ...
(Date:12/8/2016)... ... December 08, 2016 , ... The ... offices headquartered in Jefferson County, is announcing the launch of a charity drive ... The number of homeless women and children in Birmingham has grown steadily since ...
(Date:12/8/2016)... Louis, MS (PRWEB) , ... December 08, 2016 , ... ... that serve commercial and residential clients in and around the Hancock County area, is ... for the Hancock County Food Pantry. , The Hancock County Food Pantry has worked ...
(Date:12/7/2016)... PA (PRWEB) , ... December 07, 2016 , ... ... with the announcement that it is one of the early adopters completing EU-U.S. Privacy ... Framework is designed to provide companies on both sides of the Atlantic with a ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... Kenall Manufacturing, ... new MedMaster™ MPCNGX . The MPCNGX is a multi-function, sealed, LED luminaire that ... amount of light where and when it’s needed. , A 2’ x ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... , Dec 8, 2016 Research and Markets ... report to their offering. ... The global chromatography market to grow ... Global Chromatography Market 2016-2020, has been prepared based on an in-depth market ... and its growth prospects over the coming years. The report also includes ...
(Date:12/8/2016)... 8, 2016 According to ... by Product (Actual Sugars, Sugar Alcohols, Artificial Sweeteners), ... Tonicity Agents), Formulation (Oral, Topical, Parenteral) - Global ... has witnessed healthy growth during the last decade, ... of 4.3% between 2016 and 2021 to reach ...
(Date:12/8/2016)... 8, 2016  Agenovir Corporation, a company using ... therapeutics, today announced that it appointed Dirk ... a member of the board of directors. ... a deep background in both founding and building ... Agenovir, co-president of Chan Zuckerberg  Biohub and ...
Breaking Medicine Technology: