Navigation Links
Guidelines can predict early menopause in child cancer survivors
Date:8/15/2014

Girls with cancer who are most likely to become infertile after treatment can be identified using guidelines developed almost 20 years ago, new research shows.

The criteria developed in Edinburgh will help to select which girls should be offered the opportunity to freeze some tissue from their ovaries for use in the future.

Doctors are optimistic that the frozen tissue could one day help young cancer survivors to have children of their own.

Some cancer treatments can affect female fertility by bringing on early menopause. Freezing samples of ovary tissue before patients start treatment is the only option to try to preserve their fertility.

At least 30 babies have been born from frozen ovarian tissue taken from adult women but the procedure remains unproven in girls and young women.

Taking the initial samples of ovaries to be frozen involves a surgical technique and is still relatively experimental. It is therefore crucial that doctors can accurately predict which patients are most likely to benefit and when it can be safely performed.

Guidelines were developed almost 20 years ago to select which girls should be offered the procedure, based on their age, type of cancer treatment and their chances of being cured of their cancer. Now that the girls are older, doctors are able to validate their predictions.

Researchers led by the University of Edinburgh validated the criteria by looking back at more than 400 girls with cancer who were under 18 years of age when diagnosed. They found that the criteria accurately predicted all but one of the patients who entered early menopause.

The study, funded by the Medical Research Council, is published today in the journal Lancet Oncology.

The lead researcher is Professor Hamish Wallace of the University of Edinburgh's Department of Child Life and Health and Consultant Paediatric Oncologist at the Royal Hospital for Sick Children (RHSC), where the research was carried out. He said: "Advances in lifesaving treatments mean that more and more young people with cancer are surviving the disease. Here we have an opportunity to help young women to have families of their own when they grow up, if they so choose."


'/>"/>
Contact: Jen Middleton
jen.middleton@ed.ac.uk
44-131-650-6514
University of Edinburgh
Source:Eurekalert

Related medicine news :

1. Experts Issue Guidelines for Treating Irritable Bowel Syndrome
2. Colorado Braces Itself for New Medical Marijuana Guidelines and Regulations
3. Drexel University College of Medicine Research May Lead to Improved Alzheimer’s/Vascular Dementia Diagnostic Guidelines
4. Baby aspirin? Many doctors dont recommend, despite guidelines
5. Portable Monitors OK for Spotting Sleep Apnea: New Guidelines
6. LymeDisease.org Endorses New Evidence-Based Lyme Guidelines: ILADS Guidelines Allow Patients to Understand Treatment Options and Make Informed Choices
7. 2014 ESC/ESA Guidelines on non-cardiac surgery: Cardiovascular assessment and management
8. New guidelines help keep asthma out of yellow zone
9. Study: Pediatric preventive care guidelines need retooling for computerized format
10. CarePoint Health – Bayonne Medical Center Joins Get With The Guidelines–Stroke Program
11. Breast cancer: DMP is largely consistent with guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally recognized health ... expanded their existing home health joint venture through an agreement, effective October 1, ... joint venture home health company with Asante, delivering clinically integrated care, for the ...
(Date:10/12/2017)... ... 2017 , ... Dr. Parsa Mohebi, the Los Angeles based ... the newly revamped Cosmetic Town journal section, featuring articles written by ... as Follicular Unit Extraction (FUE). , Dr. Mohebi says “I enjoy ...
(Date:10/12/2017)... ... 12, 2017 , ... Leading pediatric oncology experts at Children’s National Health ... Congress of the International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired ... Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, M.D., Chief ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... been named one of Michigan’s 2017 Best and Brightest in Wellness® by Best ... in Wellness® awards program on Friday, Oct. 20 from 7:30 a.m. to 2 ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United ... year. In some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and ... havens have extremely low property-tax rates, which contributes to the relatively lower cost ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
(Date:10/2/2017)...  Eli Lilly and Company (NYSE: LLY ... quarter of 2017 on Tuesday, October 24, 2017. Lilly ... with the investment community and media to further detail ... will begin at 9 a.m. Eastern time. Investors, media ... of the conference call through a link that will ...
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host its fiscal ... Friday, November 3, 2017, beginning at 7:00 a.m. (CDT) ... a.m. (CDT) / 9:30 a.m. (EDT). In ... guidance for 2018, Hill-Rom executives will also highlight the ... long-range financial outlook through 2020. ...
Breaking Medicine Technology: