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Growth more stunted in lower-income youth with kidney disease
Date:11/21/2013

ey-Mims, a pediatric kidney specialist at the NIH's National Institute of Diabetes and Digestive and Kidney Diseases, the study's primary funder. "Although there also could be other issues like nutrition or household finances contributing to this difference, the main lesson is that we may need to learn how to help families better follow treatment plans for their children with CKD."

Dr. Susan Furth, the study's lead author and a researcher at The Children's Hospital of Philadelphia, agrees. "More aggressive intervention or other programs to help support what's happening outside the doctor's office could help. For example, more frequent contact with nurses and other medical staff could help children and families understand and follow prescribed treatments," she said.

Also, blood pressure control a factor associated with kidney disease progression improved across the groups, though children with lower SES took an average of 4.5 years to get their blood pressure down within the normal range, compared to two years for those with a higher income. However, the longer time period did not appear to result in more advanced CKD in children from low income families.

"Clearly, we need to find better ways to achieve good blood pressure control in all the children," said Furth. "Like the growth hormone question, blood pressure could be a matter of being able to afford or regularly take the medications prescribed, or genetics, or may involve factors like diet, interactions with other medications, or other exposures that could hinder the treatments from working as well for some children."

Moxey-Mims added that more research is proposed in CKiD to examine treatment adherence, and a partnership with the NIH-supported Chronic Renal Insufficiency Cohort Study (in adults) will look at associations between health literacy and SES. Health literacy is the capacity to understand basic health information to make appropriate health decisions.

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Contact: Bill Polglase
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases
Source:Eurekalert

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