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Growth Opportunities for Actemra Will Propel Roche to Sixth Position in the Rheumatoid Arthritis Market by 2012
Date:1/14/2009

Recent Entrants Invest Heavily in Promotion to Capture Share in Mature Market, According to a New Report from Decision Resources

WALTHAM, Mass., Jan. 14 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that growth opportunities for Roche/Chugai's Actemra (marketed as RoActemra in Europe) will propel Roche to sixth position in the rheumatoid arthritis market by 2012. Driving factors include Actemra's early market entry into Japan, making it the only agent available for the treatment of inadequate responders to TNF-alpha in Japan until the arrival of Bristol-Myers Squibb's Orencia in 2012, and the likelihood that the drug will be used in relatively early lines of biologic therapy.

Currently, physicians rely heavily on TNF-alpha inhibitors in early lines of biological therapy, and reserve agents with other mechanisms of action, such as Orencia and Biogen Idec/Genentech's Rituxan (also marketed by Chugai and Zenyaku Kogyo in Japan, and marketed as MabThera in Europe by Roche), largely for TNF-alpha inadequate responders. According to the new report entitled Brands & Strategies: Rheumatoid Arthritis, physicians indicate that Actemra's efficacy data is compelling enough to consider using it earlier in therapy; particularly once it has been on the market long enough to gather some post-marketing data to provide reassurance about side effects such as elevated lipid levels and elevated liver enzymes.

"Despite a recent regulatory setback in the U.S., physicians are cautiously optimistic about the efficacy of Actemra," said Dancella Fernandes, Ph.D., analyst at Decision Resources. "Decision Resources anticipates the drug's uptake as a treatment for inadequate responders to TNF-alpha will garner Actemra sales of $603 million in 201
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SOURCE Decision Resources
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