Navigation Links
Growing human GI cells may lead to personalized treatments
Date:8/7/2014

bacterial pathogens like E. coli.

This showed that pathogenic strains of E. coli attached to intestinal epithelial cells. That attachment is thought to be the critical step in stimulating disease. The investigators said the experimental system they created should lead to new methods to uncover therapies for treating bacterial infections of the intestine.

"In the past, the only really robust method for studying GI epithelial cells was to use cancer cell lines," said co-senior investigator Matthew A. Ciorba, MD, a gastroenterologist and assistant professor of medicine. "However, cancer cells behave differently than the noncancerous GI epithelium, which is affected in patients with conditions such as inflammatory bowel disease. This technique now allows us to study cells identical to the ones that live in a patient's GI tract. Plus, we can grow the cell lines quickly enough that it should be possible to develop a personalized approach to understanding a patient's disease and to tailor treatment based on a patient's underlying problem."

The researchers said the new technique is relatively simple and inexpensive and could easily be adapted for use in other laboratories.

"You can grow these cells, differentiate them and then test various therapies using these cells," Stappenbeck explained. "If we want to learn whether particular patients have a susceptibility to certain types of infections, we can test that. We're very excited about this going forward because we're entering new territory. We've never been able to do this before."

Looking ahead, the researchers believe these cell lines will be useful in testing for new drug targets, for vaccine development and to better understand how these human cells interact with the beneficial and the harmful microbes that also live in the gut.


'/>"/>

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Growing Less Invasive Technology Company, SpineFrontier Inc., Announces John Miller as VP of Sales
2. Growing Seminary Welcomes New Faculty
3. Teen Growing Pains May Persist For Years
4. Malaria Growing Resistant to Drugs Used to Fight It
5. Many people never grow out of their growing pains
6. North York Dental Provides Services to Toronto Children in Light of Growing Demand
7. New Study Shows the Growing Number of Independent Voters Have a Greater Propensity for Sleeping Well vs. Democrats or Republicans
8. "Win 25K For Your Cause": A Produce Company Taps Into Community Opinion To Find A New Social Program To Support Via “Growing Smiles, Sharing Goodness” Movement
9. Benicar Lawsuit Page Launched by Wright & Schulte LLC to Provide Updated Information on Benicar Side Effects, Growing Litigation
10. Growing Consumption of Poultry Meat Drives the Global Choline Chloride Market, According to an Upcoming Report by Global Industry Analysts, Inc.
11. Global Market for Synthetic Biology to Reach Nearly $11.9 Billion by 2018 — Enabled Products Account for the Fastest Growing Segment with 36.7% CAGR
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Growing human GI cells may lead to personalized treatments
(Date:9/22/2014)... September 19, 2014 -- Recent two-generation approaches to ... are receiving increasing attention from researchers, advocates, and ... to enable them to move to jobs that ... early care and education for children, these programs ... However, according to a new report from ...
(Date:9/22/2014)... RESTON, Va. (PRWEB) September 22, 2014 ... (WEDI), the nation’s leading nonprofit authority on ... in healthcare information exchange, announced findings from its ... unique Health Plan Identifier (HPID) within electronic transactions ... Act (HIPAA). WEDI conducted the survey from August ...
(Date:9/22/2014)... HealthDay Reporter MONDAY, Sept. 22, ... What can I do to help ensure a healthy baby? ... may play a role in reducing the risk of having ... found that mothers of children with autism were significantly less ... than those whose children seem to be developing normally. ...
(Date:9/22/2014)... 2014 Severe weather can occur with little warning, ... as part of National Preparedness Month, Amica Insurance is ... for the unexpected:, , Build an emergency supply ... and one gallon of water per person per day for at ... plan that includes pets so your family knows what to do ...
(Date:9/22/2014)... The struggles that lie in communication between ... been well-documented—reportedly, language barriers between doctors and patients are ... room and an increased likelihood for fatal consequences and ... the largest medical facility in the Fargo, ND and ... the need for Video Remote Interpreting (VRI), ...
Breaking Medicine News(10 mins):Health News:A two-generation lens: Current state policies fail to support families with young children 2Health News:WEDI Announces Survey Results from Unique Health Plan Identifier (HPID) Industry Poll 2Health News:WEDI Announces Survey Results from Unique Health Plan Identifier (HPID) Industry Poll 3Health News:Could Low Iron Intake During Pregnancy Raise Autism Risk? 2Health News:Could Low Iron Intake During Pregnancy Raise Autism Risk? 3Health News:Amica Shares Tips for National Preparedness Month 2Health News:Healthcare Cost Savings Case Study:Stratus Video Interpreting Assists Sanford Health System in Accommodating Increasing LEP Population,Saves a Predicted $100,000 Per Year 2Health News:Healthcare Cost Savings Case Study:Stratus Video Interpreting Assists Sanford Health System in Accommodating Increasing LEP Population,Saves a Predicted $100,000 Per Year 3Health News:Healthcare Cost Savings Case Study:Stratus Video Interpreting Assists Sanford Health System in Accommodating Increasing LEP Population,Saves a Predicted $100,000 Per Year 4
... LONDON: Children who attend day care or play groups ... most common type of childhood leukaemia than those who ... investigating the link. , The new research, to ... Causes and Prevention of Childhood Leukaemia Conference in London, ...
... Retire from Company -, LAVAL, QC, April ... today announced that Claire Brulle, M.D. has been ... Company. Incumbent,Chief Medical Officer Dr. Sylvie Bouchard has ... practicing medicine., "Dr. Brulle brings to Labopharm ...
... Authentidate,Holding Corp. (Nasdaq: ADAT ), ... and web-based services, today announced that United,Seating ... providers of comprehensive,seating and mobility solutions for ... platform from Authentidate(R) to facilitate its,mobility provisioning ...
... TRIANGLE PARK, N.C., April 28 Tryton Medical,Inc. ... Davis as President and,Chief Executive Officer. Founded in ... that are designed to definitively treat bifurcation,lesions., ... 20-year career with,Guidant and Eli Lilly & Company. ...
... (Oakland, Calif.) Diabetes before motherhood more than doubled ... to a Kaiser Permanente study published in the May ... previous studies have looked exclusively at gestational diabetes (diabetes ... baby is born), this is the largest and most ...
... the Universities of Exeter and Coventry have developed the ... the rapid diagnostic tests (RDTs) currently used in the ... suggest that the technique could be as effective as ... potentially viable alternative. The team is now working on ...
Cached Medicine News:Health News:New analysis finds daycare attendance early in life cuts childhood leukemia risk by 30 percent 2Health News:New analysis finds daycare attendance early in life cuts childhood leukemia risk by 30 percent 3Health News:Labopharm Appoints Dr. Claire Brulle as Senior Vice-President and Chief Medical Officer 2Health News:Leading Provider United Seating & Mobility Implements Authentidate's Inscrybe Healthcare Platform to Standardize and Streamline Administrative Processes 2Health News:Leading Provider United Seating & Mobility Implements Authentidate's Inscrybe Healthcare Platform to Standardize and Streamline Administrative Processes 3Health News:Leading Provider United Seating & Mobility Implements Authentidate's Inscrybe Healthcare Platform to Standardize and Streamline Administrative Processes 4Health News:J. Greg Davis Appointed President & Chief Executive Officer of Tryton Medical, Inc. 2Health News:Kaiser Permanente study finds diabetes doubling before motherhood 2Health News:Kaiser Permanente study finds diabetes doubling before motherhood 3Health News:Exeter engineers create new technique for malaria diagnosis 2
(Date:9/22/2014)... SHANGHAI , Sept. 22, 2014 ... global knowledge leader in healthcare technology, media and ... healthcare innovation in China ... technologies. Continua and BHG announced this new partnership ... this week in Washington, DC ...
(Date:9/22/2014)... -- Research and Markets has announced ... (Radiofrequency, Ultrasound, Irreversible Electroporation, Cryotherapy, Microwave) Market - ... On the basis of type ... been divided into eight major segments, namely, light/laser, ... ablation technologies. The light/laser ablation technology segment accounted ...
(Date:9/22/2014)... , Sept. 22, 2014  Olympus, a global ... for medical and surgical procedures, among other core ... with Munich -based Brainlab to ... Navigation. This agreement applies to the US ... U.S. sales and all distribution outside the U.S. ...
Breaking Medicine Technology:Continua and Borderless Healthcare Group Form Strategic Partnership, Launch the Healthcare Technology Innovation Center in Shanghai 2Continua and Borderless Healthcare Group Form Strategic Partnership, Launch the Healthcare Technology Innovation Center in Shanghai 3Continua and Borderless Healthcare Group Form Strategic Partnership, Launch the Healthcare Technology Innovation Center in Shanghai 4Global Ablation Technologies (Radiofrequency, Ultrasound, Irreversible Electroporation, Cryotherapy, Microwave) Market - Forecasts to 2019 2Global Ablation Technologies (Radiofrequency, Ultrasound, Irreversible Electroporation, Cryotherapy, Microwave) Market - Forecasts to 2019 3Olympus Partners with Brainlab as Exclusive Distributor for ENT Products in U.S. Market 2Olympus Partners with Brainlab as Exclusive Distributor for ENT Products in U.S. Market 3Olympus Partners with Brainlab as Exclusive Distributor for ENT Products in U.S. Market 4
... June 22, 2011 Life Technologies Corporation ... that the company has led a successful consortium ... the Oxford NIHR Biomedical Research Centre, AstraZeneca, and ... Johnson & Johnson Pharmaceutical Research & Development, L.L.C. ...
... June 22, 2011 Reportlinker.com announces that ... in its catalogue: U.S. ... http://www.reportlinker.com/p0559270/US-Urinary-Incontinence-Devices.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Food_Ingredient This research ... incontinence device market. The urinary incontinence device ...
Cached Medicine Technology:Life Technologies Consortium to Create New Frontline Diagnostic Utilising DNA Sequencing for Cancer Patients in the U.K. 2Life Technologies Consortium to Create New Frontline Diagnostic Utilising DNA Sequencing for Cancer Patients in the U.K. 3Life Technologies Consortium to Create New Frontline Diagnostic Utilising DNA Sequencing for Cancer Patients in the U.K. 4Life Technologies Consortium to Create New Frontline Diagnostic Utilising DNA Sequencing for Cancer Patients in the U.K. 5Life Technologies Consortium to Create New Frontline Diagnostic Utilising DNA Sequencing for Cancer Patients in the U.K. 6Life Technologies Consortium to Create New Frontline Diagnostic Utilising DNA Sequencing for Cancer Patients in the U.K. 7Reportlinker Adds U.S. Urinary Incontinence Devices 2Reportlinker Adds U.S. Urinary Incontinence Devices 3Reportlinker Adds U.S. Urinary Incontinence Devices 4