Navigation Links
Green Tea May Lower Lung Cancer Risk
Date:1/12/2010

Benefits seen for smokers, nonsmokers, those with certain genetic makeup

TUESDAY, Jan. 12 (HealthDay News) -- Antioxidants in green tea appear to significantly lower the risk for developing lung cancer among smokers and nonsmokers alike, new research from Taiwan reveals.

The study suggests that smokers and nonsmokers who consume a minimum of one cup of green tea per day appear to have a nearly 13-fold and fivefold lower risk, respectively, for developing lung cancer than smokers and nonsmokers who don't drink any green tea.

"The health effect of green tea consumption could modify the risk of lung cancer, particularly among smokers," said study author I-Hsin Lin, of Chung Shan Medical University in Taichung.

Lin and her team are scheduled to present their findings at a lung cancer conference this week in Coronado, Calif. The conference is sponsored by the American Association for Cancer Research and the International Association for the Study of Lung Cancer.

The observed protective effect seems to result from the strong "antioxidative property" of polyphenols found in green tea preparations.

To determine just how strong this effect might be, the authors assessed the dietary intake and lifestyle habits of 170 lung cancer patients and 340 healthy patients.

The participants completed questionnaires outlining their smoking histories, green tea consumption habits, fruit and vegetable intake, and cooking practices. Patients were also asked to note any family history of lung cancer.

Genetic testing was also conducted to assess which particular insulin-like growth factor genotype -- among several -- each participant possessed.

This analysis was considered crucial, given the author's observation that, independent of green tea consumption, genetically determined hormonal differences can affect how quickly cancer cells spread, thereby predisposing people toward a greater or lesser general risk for developing lung cancer in the first place.

While emphasizing that both smoking and nonsmoking tea drinkers generally benefited from green tea consumption relative to non-tea drinkers, the team observed that tea drinkers with particular growth factor genotypes seemed to gain even more protection -- as much as 66 percent greater protection compared with tea drinkers bearing a different genetic background.

The findings reflect solely upon the potential interplay of green tea, genetics and lung cancer risk, the researchers noted, leaving aside potential questions regarding black tea consumption.

"Our results suggest the potential health benefits of green tea consumption," concluded Lin. "However, cigarette smoking can serve as an initiator and promoter of carcinogenesis, [so] cessation of smoking is the best way for cancer prevention."

Dr. Norman Edelman, chief medical officer of the American Lung Association, emphatically agreed.

"First of all, this is not a new concept," he observed. "The idea that various antioxidants are protective to the lung has been around for a while, and green tea is a powerful antioxidant. But for us to really know whether or not just one cup can have such an enormous effect, you really have to look at more data and all the other possibly confounding factors, such as whether patients are obese, whether they are leading otherwise healthy lives, that kind of thing."

"Meanwhile, what the American Lung Association is really afraid of," cautioned Edelman, "is that people will look at this and think, 'Oh, well, I can smoke as long as I have a few cups of green tea.' Nothing could be further from the truth. Smoking is extremely toxic, obviously, and extremely detrimental to your health. And nothing changes this fact. So the most important thing here is that we don't want anyone to get the message that it's OK to smoke so long as I drink green tea."

Meanwhile, another group reported that a diet high in leafy green vegetables, folate and some multivitamins might protect against smoking-related genetic changes that lead to lung cancer.

The researchers from Lovelace Respiratory Research Institute in Albuquerque, N.M., found those substances, including vitamins C, A and K, could influence a chemical modification called cellular gene methylation. Aberrant gene methylation is known to be a mechanism in the development of cancer in smokers.

Their findings were published online Jan. 12 in Cancer Research.

Exploring yet another front in lung cancer science, a second study scheduled for release at the lung cancer conference suggests that lung cancer patients who are smokers seem better able than nonsmoking patients to tolerate higher -- and presumably more effective -- dosages of a standard chemotherapy treatment known as erlotinib.

The research team, from the Wake Forest University in Winston-Salem, N.C., found that while nonsmokers ultimately developed dangerously toxic side effects -- such as rashes, diarrhea and/or dehydration -- when placed on an average daily dose regimen of just 225 milligrams of erlotinib, smokers didn't develop similarly problematic reactions until the daily average dosage reached 300 milligrams.

More information

For additional details on green tea and lung cancer prevention, visit the National Cancer Institute.



SOURCES: I-Hsin Lin, M.S. student, Chung Shan Medical University, Taichung, Taiwan; Norman Edelman, M.D., chief medical officer, American Lung Association, Stonybrook, N.Y.; Jan. 11-14, 2010, presentations, AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer, Coronado, Calif.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Greenway Medical Technologies Deploys Integrated EHR, Practice Management and Interoperability Solution Within Bethesda Healthcare System
2. Put Some "Green" Into Gift-Giving With Eco-Friendly Footwear Products
3. Northeast Ohio Hospital System Announces New “Green” Initiative
4. EPA: Greenhouse Gases Hazardous to Your Health
5. Green tea chemical combined with another may hold promise for treatment of brain disorders
6. Text Messages from Santa
7. Santa goes GREEN by going MOBILE for The March of Dimes
8. Cutting greenhouse pollutants could directly save millions of lives worldwide
9. Statement of Robert Greenstein, Executive Director, Center on Budget and Policy Priorities, on the New Senate Health Reform Bill
10. Antifibrotic effects of green tea
11. Greenway Medical Technologies Enhances Advisory and Consulting Partnership Strategies with Regional Extension Centers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations at ... Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Issue 52" report to their offering. ... treatment creates a favourable commercial environment for MedImmune to enter. ... base that will serve to drive considerable growth for effective ... serve to cap sales considerably, but development is still in ...
(Date:6/23/2016)... , , , WHEN: ... , , , , LOCATION: , , , Online, with ... , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice ... Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... industry is witnessing an exceptional era. Several new demand spaces, such ...
(Date:6/23/2016)... Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new ... affiliate in Latin America . ... ... ... ...
Breaking Medicine Technology: