Navigation Links
Greater certainty in monitoring 3 therapeutic medications is facilitated by new CRMs
Date:11/18/2009

Rockville, Md., November 18, 2009 To help bring greater certainty to the measurement of medication levels in a patient's bloodstream for three drugs with narrow therapeutic ranges, the U.S. Pharmacopeial Convention (USP) is releasing new certified reference materials (CRMs).

The three new CRMs are for carbamazepine, an anticonvulsant and mood stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder; phenytoin, commonly used as an antiepileptic; and theophylline, used in the treatment of respiratory diseases. These three drugs are among a group of medicines that are often monitored in the bloodstream of patients that have been prescribed the drugs. Such medicines may need to be carefully monitored for a number of reasons, including a narrow therapeutic range or risk of toxicity. Therapeutic drug monitoring may also be necessary for drugs that are intended to maintain the absence (as opposed to the presence) of a medical condition, such as seizures.

CRMs represent an important step forward for USP reference standards, which are the physical materials used to demonstrate compliance to written USP standards designating a medicine and its ingredients' identity, quality, purity, strength and consistency. CRMs are reference standards accompanied by a certificate of analysis. A CRM is rigorously tested for one or more chemical or physical properties (such as purity). A property value with associated uncertainties certified to be true based on these tests is assigned to the CRM after a thorough statistical treatment of the data. The path of metrological traceability, which provides information on how the measurement was made and which standards were used to support the measurement, is included in the Certificate of Analysis, as well as the estimated level of uncertainty associated with the assigned value. This added information regarding uncertainties and traceability is provided for users of the reference materials. Procedur
'/>"/>

Contact: Francine Pierson
fp@usp.org
301-816-8588
US Pharmacopeia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Older People at Greater Risk of Swine Flu Death
2. Visiting Nurse Association of Greater Philadelphia and Philadelphia Fire DepartmentAwarded by National Fire Protection Association
3. Women Are at Greater Risk Than Men of Graft Loss After Undergoing Liver Transplantation for Hepatitis C-related Liver Disease
4. New Census Reveals Decline in Greater Los Angeles Homelessness
5. Blacks at Greater Risk for Colorectal Cancer
6. YWCA Greater Los Angeles Presents Black & White Benefactrix Ball
7. New data showed type 2 diabetes patients experienced greater blood sugar reductions
8. Increased levels of Muellerian-inhibiting substance could mean greater breast cancer risk
9. Empire BlueCross BlueShield Launches Art Heals Program with Museum for African Art, Greater New York Hospital Association
10. Largest Survey of Its Kind Finds the Psychological and Social Effects of Psoriasis Greater for Women
11. Sexual Satisfaction May Lead to Greater Well-Being in Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... August 29, 2014 Recently, iFitDress.com, the ... new selection of chic bridesmaid dresses . Included ... items. In addition, all of them are provided at ... , iFitDress.com insists on offering fast and reliable delivery ... what they order in a short time. As is ...
(Date:8/28/2014)... August 28, 2014 Blood's Thicker Than Water ... money and family ties in the heart of the city. ... – a story about how disrespect caused two families to ... many streets. , The Yayo Boyz and the M.O.B. Boyz ... speechless and local onlookers in a silent terror. "Guerrilla," AKA ...
(Date:8/28/2014)... FL (PRWEB) August 28, 2014 Millennium ... use affecting users in the workplace. A recent ... Dependence (NCADD) states that drug abuse is costing ... who use or are addicted to drugs affect their ... activities carry over into the workplace, causing expensive problems ...
(Date:8/28/2014)... government plans its exit strategy from the war, now may ... providing health care to veterans, says a Perspective piece in ... simply go on doing more of the same is to ... cost and population structure pose in the longer run," said ... Clinical Practice, and David Auerbach, from the RAND Corporation, in ...
(Date:8/28/2014)... 2014 The Governor of Yucatán, Rolando ... at a press conference; this event is organized by ... of Economy through the National Microenterprise Financing Program ( ... to the 5th at the Convention Center Yucatan Siglo ... a great responsibility for Yucatan to host the 17th ...
Breaking Medicine News(10 mins):Health News:New Selection of Chic Bridesmaid Dresses Available at iFitDress.com 2Health News:Raymond E. Blake Releases Blood's Thicker Than Water, Based on a True Story 2Health News:Drug Use Causes Problems in the Workplace 2Health News:A VA exit strategy 2Health News:Governor of the State of Yucatan presents the 17th Microcredit Summit 2Health News:Governor of the State of Yucatan presents the 17th Microcredit Summit 3
... COSTA MESA, Calif., Jan. 21 Talk About ... of a $300,000 multi-year grant from the Newport Beach ... of this generous contribution, TACA will launch three new ... program, the addition of an in house advocate to ...
... Nu Skin Enterprises, Inc. (NYSE: NUS ) today ... financial results prior to the market opening on Friday, Feb. ... a conference call with the investment community later that same ... participants can expect to hear management review past results and ...
... uninsuredsteeply rising insurance premiumsemployers cutting healthcare benefits. , ... Diagnoses, and Dollars: Facing the Ever-Expanding Market for ... America,s healthcare industry to task and challenges readers ... Provocative, timely, and comprehensively researched, this book analyzes ...
... Alliance Tech ( http://alliancetech.com ), the leader ... that Carestream Health, Inc., used the company,s ... lead opportunities with attendees at the Radiological ... in Chicago in early December. (Logo: ...
... critical for physicians to understand potential risks when communicating with ... national insurer of physician and surgeon medical liability with 44,000 ... telemedicine liability risks. , ... Napa, ...
... Tenn., Jan. 21 Healthcare Management Systems,Inc.(R) (HMS) announced ... supply a full suite of financial solutions for the ... system will provide much needed,integration for the 26-bed hospital ... also include technology to get them closer to an ...
Cached Medicine News:Health News:Talk About Curing Autism Receives $300,000 Grant From Pacific Life Foundation to Provide Services for Families Affected by Autism in Orange County 2Health News:Alliance Tech's RFID Technology Enhances Carestream Health's Capability to Connect with Key Prospects at RSNA 2Health News:Alliance Tech's RFID Technology Enhances Carestream Health's Capability to Connect with Key Prospects at RSNA 3Health News:The Doctors Company Provides Tips for Physicians to Minimize Risk While Practicing Medicine by Phone or E-mail 2Health News:The Doctors Company Provides Tips for Physicians to Minimize Risk While Practicing Medicine by Phone or E-mail 3Health News:The Doctors Company Provides Tips for Physicians to Minimize Risk While Practicing Medicine by Phone or E-mail 4Health News:Yalobusha General Hospital Selects HMS to Provide Information Technology Infrastructure 2
(Date:8/28/2014)... Del. , Aug. 28, 2014  Rigrodsky & Long, P.A.: ... of Lannett Company, Inc. (NYSE: LCI )? , ... September 10, 2013 and July 16, 2014, inclusive? , ... , Do you want to discuss your rights? ... Special Assistant United States Attorney, Timothy J. MacFall , announces ...
(Date:8/28/2014)... 28, 2014 Reportlinker.com announces that a ... catalogue: Germany Aesthetic Lasers and Energy ... http://www.reportlinker.com/p02343442/Germany-Aesthetic-Lasers-and-Energy-Devices-Market-Outlook-to-2020.html Germany Aesthetic Lasers ... Summary GlobalData,s new report, "Germany Aesthetic Lasers ... key market data on the Germany Aesthetic Lasers ...
(Date:8/28/2014)... 2014 Pharmatech initiated enrollment for its ... game-changing method for matching cancer patients to cancer ... target specific cancers, disease staging, and genetic mutations ... cancer, in the first place. The challenge that ... not be well known to the patient or ...
Breaking Medicine Technology:Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 2Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 3Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 2Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 3Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 4Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 5Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 6Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 7Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 8Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 9Enrollment in Pharmatech's Revolutionary AccessPPM Program Launches 2
... 2012 SERVE-HF, the largest study to investigate ... and outcomes of patients with stable heart failure, has enrolled ... Ltd., is the largest of its kind. This milestone brings ... to its target of approximately 1,250 participants. Principal ...
... N.J., May 18, 2012  Watson Pharmaceuticals, Inc. (NYSE: ... announced today that Paul Bisaro, Watson,s President and Chief ... the Company,s business at the Sanford C. Bernstein 28th ... at 4:00PM Eastern Time at the Waldorf-Astoria Hotel in ...
Cached Medicine Technology:Landmark Sleep Apnea, Heart Failure Study Recruits 1,000th Participant 2Landmark Sleep Apnea, Heart Failure Study Recruits 1,000th Participant 3Watson to Present at the Sanford C. Bernstein 28th Annual Strategic Decisions Conference 2
Inquire...
300 L, Racked, Filtered, Pre-sterilized, 96 tips/rack Recommended for 250 and 300 L pipettes....
... Aerosol barrier tips eliminate false signals ... designed and tested, Promega Barrier Tips ... with amplified nucleic acids (PCR(a)), radioactive ... forensic and serological specimens. , ,Promega ...
Diamond Filter Tips play a critical role in preventing aerosol-borne contamination. Also available sterilized (no need to autoclave) and certified free of detectable RNase, DNase, DNA, RNA, and prote...
Medicine Products: