Navigation Links
Grape seed promise in fight against bowel cancer
Date:2/14/2014

University of Adelaide research has shown for the first time that grape seed can aid the effectiveness of chemotherapy in killing colon cancer cells as well as reducing the chemotherapy's side effects.

Published in the prestigious journal PLOS ONE, the researchers say that combining grape seed extracts with chemotherapy has potential as a new approach for bowel cancer treatment to both reduce intestinal damage commonly caused by cancer chemotherapy and to enhance its effect.

Lead author Dr Amy Cheah says there is a growing body of evidence about the antioxidant health benefits of grape seed tannins or polyphenols as anti-inflammatory agents and, more recently, for their anti-cancer properties.

"This is the first study showing that grape seed can enhance the potency of one of the major chemotherapy drugs in its action against colon cancer cells," says Dr Cheah, researcher in the School of Agriculture, Food and Wine.

"Our research also showed that in laboratory studies grape seed taken orally significantly reduced inflammation and tissue damage caused by chemotherapy in the small intestine, and had no harmful effects on non-cancerous cells. Unlike chemotherapy, grape seed appears to selectively act on cancer cells and leave healthy cells almost unaffected."

The researchers used commercially available grape seed extract, a by-product of winemaking. Tannins extracted from the grape seed were freeze-dried and powdered. The extract was tested in laboratory studies using colon cancer cells grown in culture.

The research showed grape seed extract:

  • showed no side effects on the healthy intestine at concentrations of up to 1000mg/kg;
  • significantly decreased intestinal damage compared to the chemotherapy control;
  • decreased chemotherapy-induced inflammation by up to 55%
  • increased growth-inhibitory effects of chemotherapy on colon cancer cells in culture by 26%

"Our exp
'/>"/>

Contact: Dr. Amy Cheah
ker.cheah@adelaide.edu.au
61-433-910-099
University of Adelaide
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Biosynthetic grape-derived compound prevents progression of Alzheimers disease in mice
2. Grapefruit Juice May Give Boost to Cancer Treatment: Study
3. More New Drugs a Bad Fit With Grapefruit, Study Finds
4. Grape News: Global Wine Manufacturing Industry Market Research Report from IBISWorld has Been Updated
5. As colorectal cancer gets more aggressive, treatment with grape seed extract is even more effective
6. Westbridge Agricultural Products Announces that Botector® has been EPA Approved as an Organic Biopesticide to Prevent Gray Mold in Grapes
7. Grape seed and skin extract - a weapon in the fight against kidney disease caused by high-fat diets
8. New Study Results Suggest that Grape Seed Extract, Like that Found in Weight Loss Supplement Prescopodene, May Help Fight Kidney Disease
9. UofL scientists uncover how grapefruits provide a secret weapon in medical drug delivery
10. Active component of grape seed extract effective against cancer cells
11. Early Study Finds Some Promise for Lung Cancer Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... (PRWEB) May 05, 2015 Beverly Hills Cosmetic ... health and beauty products to be sold at the offices ... in Beverly Hills, and worldwide through an online store ... to fill the gap between dental care and beauty with ... beautiful and youthful,” says Dr. Glosman. , Dr. Glosman’s ...
(Date:5/5/2015)... New Jersey (PRWEB) May 05, 2015 ... has maintained its strong and secure credit rating of ... of Horizon BCBSNJ’s financials last week, the Wall Street ... adequacy” and “leading market position” in determining the rating ... of mind is one of our top priorities, so ...
(Date:5/5/2015)... (PRWEB) May 05, 2015 ... ) filed on behalf of men who ... their use of prescription testosterone replacement therapies ... multidistrict litigation underway in U.S. District Court, ... documents dated May 1st, defendants AbbVie, Inc., ...
(Date:5/5/2015)... CT (PRWEB) May 05, 2015 Sunny skies ... Cove Island Park as nearly 400 runners and walkers participated ... Run,” raising nearly $35,000. , The 5K and ... awareness about Lyme disease and to raise funds for tick-borne ... event created by the recent merger of Lyme ...
(Date:5/5/2015)... May 05, 2015 In a April 25, ... The Herald-Times , the Missouri State Highway Patrol (MSHP) announced ... production or use for the second year in a row. ... the FBI, reported 1,469 incidents in 2014 alone, around 15% ... around 2% of the US Population calls Indiana home, according ...
Breaking Medicine News(10 mins):Health News:Beverly Hills Dentist Arthur Glosman Launches New Dental Health And Beauty Product Line 2Health News:Horizon Blue Cross Blue Shield of New Jersey Maintains “A” Credit Rating from Standard & Poor’s 2Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 2Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 3Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 4Health News:1st Annual “Lyme Walk & Run” Event a Huge Success 2Health News:1st Annual “Lyme Walk & Run” Event a Huge Success 3Health News:A Forever Recovery Releases New Information on the Epidemic Rise Of Methamphetamine Abuse in Midwest America 2
... form of childhood disease, study says , , WEDNESDAY, Jan. ... identified a subtype of T-lymphoblastic leukemia (T-ALL) in children ... , Approximately 20 percent of children with T-ALL ... others with the disease, and doctors had been unable ...
... a provider of enterprise case management solutions that streamline ... a new Lagan Human Services Call Center solution ... in North America. The new solution is an ... range of functions depending on the programs administered, from ...
... of Wisdom(TM) as Worldwide Symbol for Cervical Cancer ... Month in the United States, a coalition of ... and others is partnering with their European counterparts ... cervical cancer worldwide. The Pearl of Wisdom ...
... Program ReviewsSEATTLE, Jan. 14 MetaStar, Wisconsin,s ... guidelines and software from Milliman Care Guidelines ... medical care reviews throughout the state. ... Care Guidelines (R) suite, MetaStar now uses ...
... Heavily in Promotion to Capture Share in Mature ... ResourcesWALTHAM, Mass., Jan. 14 Decision Resources, one ... focusing on pharmaceutical and healthcare issues, finds that ... in Europe) will propel Roche to sixth position ...
... market test, Uno Chicago Grill(R) will offer its new, ... dining chain to offer a gluten-free pizza and received ... disease, which affects approximately one percent of the population. ... during the northeastern market test prompted the company to ...
Cached Medicine News:Health News:Hard-to-Treat Leukemia Cell Subtype Identified 2Health News:Lagan Unveils Human Services Call Center Solution for North America 2Health News:U.S. and European Advocacy Groups Launch United, Global Campaign to Prevent Cervical Cancer 2Health News:U.S. and European Advocacy Groups Launch United, Global Campaign to Prevent Cervical Cancer 3Health News:U.S. and European Advocacy Groups Launch United, Global Campaign to Prevent Cervical Cancer 4Health News:Milliman Care Guidelines(R) Replaces Multiple Guideline Sets for Wisconsin QIO 2Health News:Milliman Care Guidelines(R) Replaces Multiple Guideline Sets for Wisconsin QIO 3Health News:Growth Opportunities for Actemra Will Propel Roche to Sixth Position in the Rheumatoid Arthritis Market by 2012 2Health News:Growth Opportunities for Actemra Will Propel Roche to Sixth Position in the Rheumatoid Arthritis Market by 2012 3Health News:Uno Chicago Grill(R) Rolls Out Gluten-Free Pizza Nationally 2
(Date:5/5/2015)...  Trovagene, Inc. (NASDAQ:  TROV), a developer of ... for the three months ended March 31, 2015. ... presented favorable clinical results at ASCO GI, AACR, ... Precision Cancer Monitoring platform,s ability to detect and ... cancers," said Antonius Schuh, Ph.D., chief executive officer ...
(Date:5/5/2015)... NEW YORK , May 5, 2015  IBM ... it is collaborating with more than a dozen leading ... identify and personalize treatment options for their patients. The ... cognitive capabilities to reduce from weeks to minutes the ... profile and gather relevant information from medical literature to ...
(Date:5/5/2015)... , May 5, 2015 ... at $94.9 million in 2014, and is estimated to ... of 7.8% from 2014 to 2019. Browse ... Device Market for an analysis of industry trends and ... http://www.micromarketmonitor.com/market/north-america-glaucoma-surgery-devices-8830146604.html Early ...
Breaking Medicine Technology:Trovagene, Inc. Announces First Quarter 2015 Financial Results 2Trovagene, Inc. Announces First Quarter 2015 Financial Results 3Trovagene, Inc. Announces First Quarter 2015 Financial Results 4Trovagene, Inc. Announces First Quarter 2015 Financial Results 5Trovagene, Inc. Announces First Quarter 2015 Financial Results 6Clinicians Tap Watson to Accelerate DNA Analysis and Inform Personalized Treatment Options for Patients 2Clinicians Tap Watson to Accelerate DNA Analysis and Inform Personalized Treatment Options for Patients 3Clinicians Tap Watson to Accelerate DNA Analysis and Inform Personalized Treatment Options for Patients 4Clinicians Tap Watson to Accelerate DNA Analysis and Inform Personalized Treatment Options for Patients 5Clinicians Tap Watson to Accelerate DNA Analysis and Inform Personalized Treatment Options for Patients 6North America Ophthalmology Glaucoma Surgery Device Market is Expected to Reach $138.3 Million by 2019, at a CAGR of 7.8% From 2014 to 2019 2North America Ophthalmology Glaucoma Surgery Device Market is Expected to Reach $138.3 Million by 2019, at a CAGR of 7.8% From 2014 to 2019 3
... NEW YORK, Sept. 6, 2011 ... market research report is available ... Licensing Strategies of Large ... Pipelines and the Patent Cliff ...
... Global regenerative medicine company, Mesoblast Limited, (ASX: ... from the European Medicines Agency (EMA) to begin ... Europe for its lead cardiovascular product Revascor(TM) in ... heart failure after a major heart attack. Revascor(TM) ...
Cached Medicine Technology:Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 2Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 3Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 4Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 5Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 6Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 7Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 8Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 9Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 10Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 11Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 12Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 13Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 14Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 15Licensing Strategies of Large Pharmaceutical Companies - Weak R&D Pipelines and the Patent Cliff Stimulate In-Licensing Activity 16Mesoblast Receives Clearance to Begin First European Trial of Allogeneic or 'Off-The-Shelf' Stem Cell Treatment for Heart Attacks 2Mesoblast Receives Clearance to Begin First European Trial of Allogeneic or 'Off-The-Shelf' Stem Cell Treatment for Heart Attacks 3Mesoblast Receives Clearance to Begin First European Trial of Allogeneic or 'Off-The-Shelf' Stem Cell Treatment for Heart Attacks 4
Eye Bank Specular Microscope. Specular microscope for easy examination of corneal slice extracted from a donor....
... system uses prolene as thread-guide reducing time and ... Probe is inserted into the nasolacrimal duct and ... The probe is then withdrawn leaving the polypropylene ... diam silicone tubing into place. Newly coated with ...
To maintain the conjunctival cul-de-sacs after enucleation or evisceration without hindering lid closure....
... conforms to natural anatomy of the ... on disposable inserter/dilator instrument for ease ... The Micro-Large plugs feature the unique ... shape of the eyelid. The slightly ...
Medicine Products: