Navigation Links
Grape powder blocks genes linked to colon cancer
Date:11/14/2007

Irvine, Calif., Nov. 14, 2007 Low doses of freeze-dried grape powder inhibit genes linked to the development of sporadic colorectal cancer, University of California, Irvine cancer researchers found.

The study suggests that a diet rich in grapes may help prevent the third most common form of cancer, one that kills more than a half a million people worldwide each year. Around 7 percent of all Americans develop colon cancer during their lifetimes.

Led by Dr. Randall Holcombe, director of clinical research at the Chao Family Comprehensive Cancer Center at UC Irvine, the study followed up on previous in vitro studies showing that resveratrol, a nutritional supplement derived from grape extract, blocks a cellular signaling pathway known as the Wnt pathway. The Wnt pathway has been linked to more than 85 percent of sporadic colon cancers, which is the most common form of colon cancer.

The UC Irvine researchers conducted their study with colon cancer patients. One group was given 20 milligrams daily of resveratrol as a pill; another drank 120 grams daily of grape powder mixed in water; and a third drank 80 grams daily of grape powder.

While the supplements did not have an impact on existing tumors, biopsied colon tissue showed that Wnt signaling in the patients taking 80 grams of grape powder was significantly reduced. Similar changes were not seen in patients taking the higher dose of grape powder or the resveratrol pills.

The researchers arent certain why the lower dose of grape powder was more effective than the higher one. However, they believe that the active components in the grapes may have different effects at low dose than they do at high dose, which is a fairly common finding in nutritional studies.

Holcombe and his colleagues will present their study results Nov. 16 at the Society for Integrative Oncologys Fourth International Conference in San Francisco.

This is truly exciting, because it
'/>"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-285-6455
University of California - Irvine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Adams Respiratory Therapeutics Announces FDA Approval of Grape-Flavored Delsym(R)
2. New All-Natural Dietary Supplement Made from Muscadine Grape Skins Helps Inhibit Growth of Certain Cancers
3. Red wine and grape juice help defend against food-borne diseases, according to MU researchers
4. Grape Consumption Improves Antioxidant Capacity in Humans
5. Researchers study potential health benefits of natural chemicals in muscadine grape seeds
6. Grapes in Diet Decrease Risk of Hypertensive Heart Failure
7. A grape future for Alzheimers disease research
8. Eating Grapes May Protect Against Alzheimers Disease
9. New Generation Xcelodose(R)S Precision Drug Powder Micro-filling System Offers 50% Increased Throughput
10. Cholesterol byproduct blocks heart health benefits of estrogen
11. Toy Blocks Might Boost Toddlers Language Skills
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... 2014 Dr. Vu Ho, a Dallas ... his practice and med-spa with the addition of new ... of cosmetic treatments and services. , “Silk Peel is ... says Dr. Ho. “As a result it can address ... sun spots, discolorations or blemishes.” , Similar to microdermabrasion, ...
(Date:12/24/2014)... TX (PRWEB) December 25, 2014 The ... to 2023” focuses on the current treatment landscape, unmet ... cancer market. Stivarga is a drug which is used ... drug is orally administered and is also prescribed to ... drug which is FDA approved is a multi-kinase inhibitor ...
(Date:12/24/2014)... (HealthDay News) -- The holidays can be a challenge for ... certain foods and drinks. "This is the season in ... of migraine," Dr. David Dodick, chair of the American Migraine ... "It,s important to think through food and beverage choices, to ... Dodick, a professor of neurology at the Mayo Clinic in ...
(Date:12/24/2014)... 24, 2014 (HealthDay News) -- Researchers say they have ... develop into eggs and sperm. While this had ... the first time that these types of cells -- ... using human stem cells, according to the team at ... of primordial germ cells is one of the earliest ...
(Date:12/24/2014)... 2014 Gluten, a protein found predominately ... have an intolerance to gluten, causing side effects that ... headaches, joint pain and fatigue. For this reason, Diet ... that deliver safe and fast weight loss while teaching ... gluten allergy reaction. These gluten free diet plans combine ...
Breaking Medicine News(10 mins):Health News:Dr. Vu Ho Expands Facial Plastic Surgery Practice to Include New Skin Care Treatment 2Health News:Stivarga Colorectal Cancer Treatment Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Stivarga Colorectal Cancer Treatment Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Expert Offers Tips for Preventing Holiday Migraines 2Health News:Diet Doc Adds Gluten Free Diet Plans to Their Stable of Specialized Weight Loss Programs 2Health News:Diet Doc Adds Gluten Free Diet Plans to Their Stable of Specialized Weight Loss Programs 3
... for Helicobacter pylori as the decay-accelerating factor (DAF), a ... , Blocking this interaction could lead to new drugs ... gastric cancer. The research appears as the ‘Paper of ... Journal of Biological Chemistry, an American Society for Biochemistry ...
... In a new clinical development partnership being launched ... arm, Cancer Research Technology (CRT) plans to take ... for not showing enough commercial promise following their ... new treatments from anti-cancer drugs that have been ...
... by the defence attorneys of the AIIMS hospital, has sought ... where a boy, suffering from cancer, got inflicted with AIDS ... ,The victim, who was nine years old at the ... for treatment of cancer, supposedly has contracted HIV due to ...
... drug Zoloft (sertraline) may avoid in preventing recurring of ... interval between the depressive episodes. ,One in every ... the study, reports foodconsumer.org. ,Researchers studied 152 ... recovered from depression during treatment with Zoloft -- 79 ...
... recent conducted at University of Michigan Health Systems in ... greater expectations of doom from their screening //mammography for ... not these expectations were unusually high or unrealistic. ... an outpatient clinic for screening mammography. The participants were ...
... Computer keyboards used in hospitals are a reservoir for ... to be disinfected every day, a new study warns.// ... various locations inside University of North Carolina hospitals and ... two types of bacteria, reports the science portal HealthCentral. ...
Cached Medicine News:Health News:Receptor for H.pylori Identified in Stomach 2Health News:Cancer Research UK Offers New Hope To Cancer Patients 2Health News:A Boy Undergoing Treatment For Cancer Gets AIDS At AIIMS 2Health News:Most Women Have Unrealistic Expectations From Screening Mammography 2Health News:Computer Keyboards In Hospitals Could Spread Infection To Patients 2
(Date:12/24/2014)... , Dec. 24, 2014  Actavis plc ... the Company has received a complete response letter ... for its New Drug Application (NDA) for the ... the treatment of hypertension.   Photo - ... are disappointed in the receipt of a complete ...
(Date:12/24/2014)... Trade Commission (ITC) issued its final decision in the case ... issued on December 23, the ITC ruled in favor of ... invalid. BMC President, James Xu called ... the ITC,s decision in this case. This victory for us ... beginning on the key patents in the case. ResMed chose ...
(Date:12/24/2014)... -- PuraMed BioScience®, Inc., (OTC Pink: PMBS), a researcher, ... products, announced it received the initial funding to begin ... relief product, for planned distribution to 1,000 medical and ... Washington State , and ... Advanced headache relief gel formulation completed, PuraMed BioScience has ...
Breaking Medicine Technology:Actavis Confirms Complete Response Letter for Nebivolol/Valsartan Fixed-Dose Combination for Hypertension 2Actavis Confirms Complete Response Letter for Nebivolol/Valsartan Fixed-Dose Combination for Hypertension 3Actavis Confirms Complete Response Letter for Nebivolol/Valsartan Fixed-Dose Combination for Hypertension 4ITC Final Decision Goes Against ResMed (RMD) Monumental Win for 3B/BMC 2PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 2PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 3
... announces that a new market research report is available ... Industry http://www.reportlinker.com/p0330474/US-Prebiotics-Industry.html ... for Prebiotics in Metric Tons and US$ Million. The ... segments: Mannan-Oligosaccharide (MOS), Fructans (Fructo-Oligosaccaride (FOS), Inulin), and Others. ...
... 2011 VWR International, LLC, a global leader in ... has acquired AMRESCO Inc., a manufacturer and supplier of ... Sciences, Proteomics, Clinical and Histology areas of research and ... VWR,s strategic investments in delivering world-class solutions and services ...
Cached Medicine Technology:US Prebiotics Industry 2US Prebiotics Industry 3US Prebiotics Industry 4US Prebiotics Industry 5US Prebiotics Industry 6US Prebiotics Industry 7VWR International, LLC Acquires AMRESCO Inc. 2
... Tissue Sectioning System has maintained the reputation ... Researchers from around the globe have relied ... fresh and fresh fixed tissue sectioning needs ... the Vibratome Automatic Tissue Sectioning Systems, the ...
Replacement bulb for Vibratome light system....
Injector blades come ten to an injector and allow for the easy replacement of Vibratome cutting blades....
Vibratome Specimen Adhesive is a special formulation developed by a major adhesive manufacturer for applications such as tissue mounting. The advantage of this adhesive is that it has a strong holdi...
Medicine Products: