Navigation Links
Grape powder blocks genes linked to colon cancer
Date:11/14/2007

Irvine, Calif., Nov. 14, 2007 Low doses of freeze-dried grape powder inhibit genes linked to the development of sporadic colorectal cancer, University of California, Irvine cancer researchers found.

The study suggests that a diet rich in grapes may help prevent the third most common form of cancer, one that kills more than a half a million people worldwide each year. Around 7 percent of all Americans develop colon cancer during their lifetimes.

Led by Dr. Randall Holcombe, director of clinical research at the Chao Family Comprehensive Cancer Center at UC Irvine, the study followed up on previous in vitro studies showing that resveratrol, a nutritional supplement derived from grape extract, blocks a cellular signaling pathway known as the Wnt pathway. The Wnt pathway has been linked to more than 85 percent of sporadic colon cancers, which is the most common form of colon cancer.

The UC Irvine researchers conducted their study with colon cancer patients. One group was given 20 milligrams daily of resveratrol as a pill; another drank 120 grams daily of grape powder mixed in water; and a third drank 80 grams daily of grape powder.

While the supplements did not have an impact on existing tumors, biopsied colon tissue showed that Wnt signaling in the patients taking 80 grams of grape powder was significantly reduced. Similar changes were not seen in patients taking the higher dose of grape powder or the resveratrol pills.

The researchers arent certain why the lower dose of grape powder was more effective than the higher one. However, they believe that the active components in the grapes may have different effects at low dose than they do at high dose, which is a fairly common finding in nutritional studies.

Holcombe and his colleagues will present their study results Nov. 16 at the Society for Integrative Oncologys Fourth International Conference in San Francisco.

This is truly exciting, because it
'/>"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-285-6455
University of California - Irvine
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Adams Respiratory Therapeutics Announces FDA Approval of Grape-Flavored Delsym(R)
2. New All-Natural Dietary Supplement Made from Muscadine Grape Skins Helps Inhibit Growth of Certain Cancers
3. Red wine and grape juice help defend against food-borne diseases, according to MU researchers
4. Grape Consumption Improves Antioxidant Capacity in Humans
5. Researchers study potential health benefits of natural chemicals in muscadine grape seeds
6. Grapes in Diet Decrease Risk of Hypertensive Heart Failure
7. A grape future for Alzheimers disease research
8. Eating Grapes May Protect Against Alzheimers Disease
9. New Generation Xcelodose(R)S Precision Drug Powder Micro-filling System Offers 50% Increased Throughput
10. Cholesterol byproduct blocks heart health benefits of estrogen
11. Toy Blocks Might Boost Toddlers Language Skills
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... May 21, 2013 The birth control ... women who have used the contraceptive NuvaRing. A new ... blood clot injuries has increased in recent months*. , ... drugs and devices with the latest safety alerts, recalls, ... others are experiencing similar side effects and decide if ...
(Date:5/20/2013)... CA (PRWEB) May 21, 2013 USA ... A Transcendent Approach to Peak Performance" won the top ... Non-Fiction Category. Chosen over a multitude of international ... global attention and critical acclaim from both mainstream and ... levels - mentally, physically and spiritually. , ...
(Date:5/20/2013)... 21, 2013 The automated external ... into two categories - semi-automated and fully automated ... into five categories, namely, hospitals, pre-hospital, public access, ... till 2017. Automated external defibrillators play an important ... arrest victims. Considering the life-saving potential of AEDs, ...
(Date:5/20/2013)... Los Angeles, CA (PRWEB) May 20, 2013 ... light on the importance of using green and ... Canadian federal government has implemented regulations to promote ... for the Packaging and Labelling Services industry ... also supported this trend,” says IBISWorld industry analyst ...
(Date:5/20/2013)... (PRWEB) May 20, 2013 In order to ... health and wellness team from DrSmartphoneMD launched an article series ... sunburns. , The series launched with the precautions ... members of the DrSmartphoneMD program are not one of the ... explained that more than 90% of all skin cancer cases ...
Breaking Medicine News(10 mins):Health News:DrugRisk Update Shows Increase in NuvaRing Blood Clot Lawsuits 2Health News:Mystic Ink Publishing's "The Infinity Zone" Wins Top Honor - International Book Awards 2Health News:Mystic Ink Publishing's "The Infinity Zone" Wins Top Honor - International Book Awards 3Health News:North America Leads Automated External Defibrillator Market (AED), Says New Research Report at ReportsnReports.com 2Health News:North America Leads Automated External Defibrillator Market (AED), Says New Research Report at ReportsnReports.com 3Health News:Packaging and Labelling Services in Canada Industry Market Research Report Now Available from IBISWorld 2Health News:Packaging and Labelling Services in Canada Industry Market Research Report Now Available from IBISWorld 3Health News:Combat Skin Cancer In Summer Months 2
... ... mental health illness stereotypes , ... Arlington, VA (PRWEB) October 28, 2009 -- As Halloween approaches, the ... alert" for costumes and other seasonal attractions that feature inaccurate and offensive stereotypes ...
... DENVER, Oct. 28 Many medical practices are struggling. ... making basic business mistakes, according to Andrew Graham, MBA, ... top reasons practices struggle, said Graham. , ... to include goals for revenue generation, customer service, performance ...
... 28 Vanda Pharmaceuticals Inc. (Vanda) (Nasdaq: VNDA ... commercialization of clinical-stage product candidates for central nervous system ... quarter ended September 30, 2009, on Monday, November 2, ... of the release will be disseminated at that time. ...
... Oct. 28 The cutting-edge of assistive technology--including ... showcased at the Assistive Technology Pavilion at Abilities ... 6-8, 2009 at the Cobb Galleria Convention Center. ... caregivers and healthcare professionals are expected to attend ...
... 28 What happens when intended parents cross international borders ... of Mumbai, India-based law firm Menon & Associates ( ... Family Solutions was among the panel speakers on ... Association Section of Family Law recently held in Montreal, Canada. ...
... , NASDAQ: CRME ... /PRNewswire-FirstCall/ - Cardiome Pharma Corp. (NASDAQ: CRME/TSX: COM) and its ... patient enrolment has begun for the ACT 5 trial, a ... a drug product candidate under development for the rapid conversion ...
Cached Medicine News:Health News:NAMI Issues "Stigma Alert" Over Inaccurate and Offensive Halloween Costumes, Attractions 2Health News:NAMI Issues "Stigma Alert" Over Inaccurate and Offensive Halloween Costumes, Attractions 3Health News:The Top 10 Business Mistakes Made By Physician Practices 2Health News:Vanda Pharmaceuticals to Announce Third Quarter 2009 Financial Results on November 2, 2009 2Health News:Experience the Future of Assistive Technology at Abilities Expo on November 6-8, 2009 2Health News:Legislation in India to Address Assisted Reproductive Technology, Egg Donation and Surrogacy 2Health News:Cardiome And Astellas Announce Initiation Of Patient Enrolment In ACT 5 Trial 2Health News:Cardiome And Astellas Announce Initiation Of Patient Enrolment In ACT 5 Trial 3Health News:Cardiome And Astellas Announce Initiation Of Patient Enrolment In ACT 5 Trial 4
(Date:5/20/2013)... , May 20, 2013 Decision ... advisory firms for pharmaceutical and healthcare issues, finds ... therapies offering a greater effect on quality of ... need. Given the high level of subjectivity and ... life, interviewed thought leaders state that it is ...
(Date:5/19/2013)...  Whole-cell pertussis vaccines were more effective at protecting ... recent outbreak, according to a new Kaiser Permanente study ... called DTwP, were available from the 1940s to 1990s, ... to the development of acellular pertussis vaccines, which are ... the United States had switched from whole-cell ...
(Date:5/18/2013)... FRANCISCO , May 18, 2013 ... MadinAmerica.com , Occupy Psychiatry , ... mental health care, announces a social media campaign ... the traditional psychiatric model, which focuses on pathology ... launch coincides with the American Psychiatric Association,s (APA) ...
Breaking Medicine Technology:For Chronic Obstructive Pulmonary Disease, Surveyed Pulmonologists Indicate That Improved Effect on Quality of Life is One of the Greatest Unmet Needs 2Study Shows Whole-Cell Vaccine was More Effective than Acellular Vaccine During California Pertussis Outbreak 2Study Shows Whole-Cell Vaccine was More Effective than Acellular Vaccine During California Pertussis Outbreak 3Study Shows Whole-Cell Vaccine was More Effective than Acellular Vaccine During California Pertussis Outbreak 4New Social Media Campaign Features Stories Of Individuals Who Rejected Psychiatric Diagnoses 2New Social Media Campaign Features Stories Of Individuals Who Rejected Psychiatric Diagnoses 3
... RA Signs and Symptoms Compared to Placebo, ... (Nasdaq: TRBN ) today announced preliminary ... double-blind, placebo-controlled, multicenter,clinical trial of its TRU-015 ... indicated that Trubion,s TRU-015 product candidate, at,well-tolerated ...
... Calif., Sept. 10 Peregrine,Pharmaceuticals, Inc. (Nasdaq: ... antibodies for the treatment of cancer and,hepatitis C ... submitted a,clinical protocol with the Drug Controller General ... safety and efficacy trial of bavituximab in combination,with ...
Cached Medicine Technology:Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis 2Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis 3Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis 4Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis 5Peregrine Pharmaceuticals Submits Clinical Protocol to Initiate Bavituximab Phase II Trial in Patients With Metastatic Breast Cancer 2Peregrine Pharmaceuticals Submits Clinical Protocol to Initiate Bavituximab Phase II Trial in Patients With Metastatic Breast Cancer 3Peregrine Pharmaceuticals Submits Clinical Protocol to Initiate Bavituximab Phase II Trial in Patients With Metastatic Breast Cancer 4
Anorectal Stylet for LATITUDE® Air-Charged Catheter...
Omnilink Adapter Cable for LATITUDE® Air-Charged Catheter...
Solid State Manometry Catheter Accessory., ,Manometric calibrators are required for calibration of solid state catheters., ,Each type of catheter requires a unique calibrator....
... The ITREL 3 is a battery ... in the U.S., ,Enterra™ Therapy is ... and vomiting associated with gastroparesis when conventional ... of symptons for diabetic or idiopathic patients., ...
Medicine Products: