Navigation Links
Grape Seed Extract Kills Leukemia Cells in Lab
Date:12/31/2008

Finding might lead to new treatment for blood cancers, researchers say

WEDNESDAY, Dec. 31 (HealthDay News) -- More than three-quarters of laboratory leukemia cells exposed to an extract from grape seeds died within 24 hours, effectively killing themselves while leaving other cells unharmed, a new study shows.

University of Kentucky researchers say they found that the extract activates JNK, a protein that regulates the cell-signaling pathway the leads to cell death, or apoptosis.

The findings appear in the Jan. 1 issue of Clinical Cancer Research.

"These results could have implications for the incorporation of agents such as grape seed extract into prevention or treatment of hematological malignancies and possibly other cancers," study author Xianglin Shi, a professor in the Graduate Center for Toxicology at the University of Kentucky, said in a news release issued by the journal's publisher.

Shi cautioned that the research is still preliminary: "This is very promising research, but it is too early to say this is chemo-protective."

Previous studies have shown that eating vegetables and fruits helps prevent cancer development and that flavonoids and grape seed extract might cause cancer cell death and reduce certain tumors.

Shi treated the leukemia cells with a commercially available grape seed extract in different doses. The higher doses caused more apoptosis in the leukemia cells, yet did not affect normal, healthy cells.

The extract proved ineffective, though, when researchers added an agent to it that inhibited the JNK protein or used genetic engineering to shut down the JNK gene.

More information

The National Center for Complementary and Alternative Medicine has more about grape seed extract.



-- Kevin McKeever



SOURCE: American Association for Cancer Research, news release, Dec. 31, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Substance in Red Grapes and Wine Key to Alzheimer's Disease
2. Release of Kowalski Book on Attaining Healthy Blood Pressure Coincides with Website Launch, New Endurance Products SR L-Arginine and Grape Seed Extract
3. Study indicates grape seed extract may reduce cognitive decline associated with Alzheimers disease
4. Potential new role for red grape seeds in treatment of Alzheimers disease
5. Drinking polyphenol-rich Concord grape juice may improve memory in older adults
6. Grapefruit Compound Inhibits Hepatitis C Virus
7. Antioxidant benefits of POM Wonderful 100% pomegranate juice top red wine, grape and acai juices
8. Grapefruit compound may help combat hepatitis C infection
9. Grape powder blocks genes linked to colon cancer
10. Eating Grapes May Protect Against Alzheimers Disease
11. A grape future for Alzheimers disease research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Grape Seed Extract Kills Leukemia Cells in Lab
(Date:2/12/2016)... ... February 12, 2016 , ... Every winter, someone is killed, injured ... West Penn Burn Center, part of the Allegheny Health Network, has partnered ... you the “Space Heaters Need Space” campaign. , “Space Heaters Need Space” ...
(Date:2/12/2016)... ... February 12, 2016 , ... AssureVest Insurance Group, a locally ... a charity drive that will raise funds earmarked to purchase computers and software for ... School. , “My school is in a low-income area and has more than 60 ...
(Date:2/12/2016)... ... 2016 , ... Vail knee specialist Robert LaPrade, MD, PhD was ... The list consists of physicians establishing, leading and partnering with ambulatory surgery centers across ... Ambulatory Surgery Center, also known as an ASC, is a modern health care facility ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... ... of the Pittsburgh metro area, celebrates the beginning of the latest charity campaign ... develop social skills through art. Donations to this worthy cause are currently being ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... Miami Dental ... implants to their Miami dental office. Beginning in January, Miami Dental Specialists will ... Miami Dental Specialists are the first office to be chosen by the dental implant ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... PAULO , Feb. 12, 2016 ... commenced a cash tender offer (the "Tender Offer") ... million outstanding aggregate principal amount of its 6.500% ... and ISIN Nos. US44915JAA88/ USP5246AAF05) (the "Notes"). In ... soliciting (the "Consent Solicitation") consents (the "Consents") of ...
(Date:2/12/2016)... PLATTSBURGH, NY , Feb. 12, 2016 /PRNewswire/ - Demers Ambulances ... Florida to Okaloosa County ... 164 Type III ambulances and one LT2 van. Quality Emergency ... Demers dealer, is responsible for the sale.  This is the ... Benoit LaFortune , Executive Vice President at Demers. --> ...
(Date:2/12/2016)... 2016  SI-BONE, Inc., a medical device company that pioneered the ... invasive surgical (MIS) device indicated for fusion for certain disorders of ... the Medicare Administrative Contractor (MAC) covering the states of ... , Massachusetts , Minnesota ... , Rhode Island , Vermont ...
Breaking Medicine Technology: