Navigation Links
Grape Seed Extract Kills Leukemia Cells in Lab
Date:12/31/2008

Finding might lead to new treatment for blood cancers, researchers say

WEDNESDAY, Dec. 31 (HealthDay News) -- More than three-quarters of laboratory leukemia cells exposed to an extract from grape seeds died within 24 hours, effectively killing themselves while leaving other cells unharmed, a new study shows.

University of Kentucky researchers say they found that the extract activates JNK, a protein that regulates the cell-signaling pathway the leads to cell death, or apoptosis.

The findings appear in the Jan. 1 issue of Clinical Cancer Research.

"These results could have implications for the incorporation of agents such as grape seed extract into prevention or treatment of hematological malignancies and possibly other cancers," study author Xianglin Shi, a professor in the Graduate Center for Toxicology at the University of Kentucky, said in a news release issued by the journal's publisher.

Shi cautioned that the research is still preliminary: "This is very promising research, but it is too early to say this is chemo-protective."

Previous studies have shown that eating vegetables and fruits helps prevent cancer development and that flavonoids and grape seed extract might cause cancer cell death and reduce certain tumors.

Shi treated the leukemia cells with a commercially available grape seed extract in different doses. The higher doses caused more apoptosis in the leukemia cells, yet did not affect normal, healthy cells.

The extract proved ineffective, though, when researchers added an agent to it that inhibited the JNK protein or used genetic engineering to shut down the JNK gene.

More information

The National Center for Complementary and Alternative Medicine has more about grape seed extract.



-- Kevin McKeever



SOURCE: American Association for Cancer Research, news release, Dec. 31, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Substance in Red Grapes and Wine Key to Alzheimer's Disease
2. Release of Kowalski Book on Attaining Healthy Blood Pressure Coincides with Website Launch, New Endurance Products SR L-Arginine and Grape Seed Extract
3. Study indicates grape seed extract may reduce cognitive decline associated with Alzheimers disease
4. Potential new role for red grape seeds in treatment of Alzheimers disease
5. Drinking polyphenol-rich Concord grape juice may improve memory in older adults
6. Grapefruit Compound Inhibits Hepatitis C Virus
7. Antioxidant benefits of POM Wonderful 100% pomegranate juice top red wine, grape and acai juices
8. Grapefruit compound may help combat hepatitis C infection
9. Grape powder blocks genes linked to colon cancer
10. Eating Grapes May Protect Against Alzheimers Disease
11. A grape future for Alzheimers disease research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Grape Seed Extract Kills Leukemia Cells in Lab
(Date:5/26/2017)... , ... May 26, 2017 , ... Dr. Alex Rabinovich, ... to announce a new, informational blog post on insurance options. If a Bay Area ... plans may help save time and money. Visiting an in-network provider for a second ...
(Date:5/26/2017)... , ... May 26, 2017 , ... “THE FLINTHILLS FAMILY-Our Journey to the Cross”: the ... Journey to the Cross” is the creation of published authors, Bob and Margaret Massey. ... to say, he is "panther quick and leather tough." His love for others is ...
(Date:5/26/2017)... ... May 26, 2017 , ... “Just What Happened in the Garden of Eden”: retells the ... of Eden” is the creation of published author, Penelope Colt, mother, trader, horse farmer, artist ... to NYC when she was three. At six, they moved to Dayton, Ohio, where ...
(Date:5/26/2017)... ... May 26, 2017 , ... Water damage to the flooring of several classrooms ... left education officials with a number of critical issues to address before students could ... be accomplished with little or no disruption to class schedules. Second, the project had ...
(Date:5/24/2017)... Ca (PRWEB) , ... May 24, 2017 , ... ... effects and background. Understanind and choosing the most appropriate instruments for research and ... critical in research finding. This webinar will focus on innovations in stereo microscopy ...
Breaking Medicine News(10 mins):
(Date:5/15/2017)... 2017  Amy Baxter MD, chief executive officer and ... pain relief, was awarded a 2017 Top 40 Healthcare ... recognized at the MM&M Top 40 Healthcare Transformers dinner ... on May 10, 2017. The dinner followed a ... "beyond the pill."  "Innovation goes beyond invention," ...
(Date:5/10/2017)... Hologic, Inc. (Nasdaq: HOLX ) ... second quarter ended April 1, 2017 .   GAAP ... compared to the prior year period as the sale ... gain, while non-GAAP diluted EPS of $0.50 increased 6.4%.  ... constant currency terms.  Excluding the effects of blood screening ...
(Date:5/10/2017)... Md. , May 10, 2017 CSSi, ... solutions for the clinical research industry, is proud to ... www.CSSiEnroll.com . The new website features both enriched content ... user experience and enhances the company,s already well-established position ... industry. "After many months of hard ...
Breaking Medicine Technology: