Navigation Links
Grape Seed Extract Kills Leukemia Cells in Lab
Date:12/31/2008

Finding might lead to new treatment for blood cancers, researchers say

WEDNESDAY, Dec. 31 (HealthDay News) -- More than three-quarters of laboratory leukemia cells exposed to an extract from grape seeds died within 24 hours, effectively killing themselves while leaving other cells unharmed, a new study shows.

University of Kentucky researchers say they found that the extract activates JNK, a protein that regulates the cell-signaling pathway the leads to cell death, or apoptosis.

The findings appear in the Jan. 1 issue of Clinical Cancer Research.

"These results could have implications for the incorporation of agents such as grape seed extract into prevention or treatment of hematological malignancies and possibly other cancers," study author Xianglin Shi, a professor in the Graduate Center for Toxicology at the University of Kentucky, said in a news release issued by the journal's publisher.

Shi cautioned that the research is still preliminary: "This is very promising research, but it is too early to say this is chemo-protective."

Previous studies have shown that eating vegetables and fruits helps prevent cancer development and that flavonoids and grape seed extract might cause cancer cell death and reduce certain tumors.

Shi treated the leukemia cells with a commercially available grape seed extract in different doses. The higher doses caused more apoptosis in the leukemia cells, yet did not affect normal, healthy cells.

The extract proved ineffective, though, when researchers added an agent to it that inhibited the JNK protein or used genetic engineering to shut down the JNK gene.

More information

The National Center for Complementary and Alternative Medicine has more about grape seed extract.



-- Kevin McKeever
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Substance in Red Grapes and Wine Key to Alzheimer's Disease
2. Release of Kowalski Book on Attaining Healthy Blood Pressure Coincides with Website Launch, New Endurance Products SR L-Arginine and Grape Seed Extract
3. Study indicates grape seed extract may reduce cognitive decline associated with Alzheimers disease
4. Potential new role for red grape seeds in treatment of Alzheimers disease
5. Drinking polyphenol-rich Concord grape juice may improve memory in older adults
6. Grapefruit Compound Inhibits Hepatitis C Virus
7. Antioxidant benefits of POM Wonderful 100% pomegranate juice top red wine, grape and acai juices
8. Grapefruit compound may help combat hepatitis C infection
9. Grape powder blocks genes linked to colon cancer
10. Eating Grapes May Protect Against Alzheimers Disease
11. A grape future for Alzheimers disease research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Grape Seed Extract Kills Leukemia Cells in Lab
(Date:7/29/2014)... PA (PRWEB) July 29, 2014 ... the Sewickley and Moon Township areas, has affiliated with ... Women’s Health will continue to deliver babies and perform ... need of advanced care will be referred to Allegheny ... are proud to be associated with West Penn Hospital ...
(Date:7/29/2014)... Representatives with BNatrl announced today that ... BNatrl Silver Solution 12ppm . , “It’s safe for ... BNatrl LLC. “It helps boost your immune system and ... and microbes.” , BNatrl develops and manufactures organic food ... 10 percent of profits being used to fund projects ...
(Date:7/29/2014)... 2014 Regents Health Resources, a consulting ... brought health care industry veteran Daryl Demonbreun and former ... lead the company’s ambitious plans to grow into a ... been moving along at a steady pace for nearly ... a notch,” says Bob Maier, founder and chief executive ...
(Date:7/29/2014)... According to the new market research report, "Fingerprint ... (Optical Prism, Pizeoelectric, Capacitive, and Adhesives), Application (Mobile ... & Finance), and Geography - Global Trends & ... the global Fingerprint Sensors Market is projected to ... high CAGR of 16.8% from 2014 to 2020. ...
(Date:7/29/2014)... This Latest Guidebook for Conducting Pharma ... Edition) not only provided a comprehensive and thorough knowledge ... imported drug registration but also introduced the practical operation ... you to use the Chinese trial venues to keep ... step by step. , The audiences of this guidebook ...
Breaking Medicine News(10 mins):Health News:Leading West Suburban OBGYN Practice, Premier Women’s Health, Joins Allegheny Health Network 2Health News:Leading West Suburban OBGYN Practice, Premier Women’s Health, Joins Allegheny Health Network 3Health News:BNatrl Launches New Silver Solution Product 2Health News:Sferrella and Demonbruen Join Regents Health Resources 2Health News:Fingerprint Sensors Market by Type (Swipe And Area) Estimated to Reach $14.35 Billion by 2020 - New Report by MarketsandMarkets 2Health News:Fingerprint Sensors Market by Type (Swipe And Area) Estimated to Reach $14.35 Billion by 2020 - New Report by MarketsandMarkets 3Health News:Fingerprint Sensors Market by Type (Swipe And Area) Estimated to Reach $14.35 Billion by 2020 - New Report by MarketsandMarkets 4Health News:Pharma Clinical Trials Market in China: Authorities for Drug New Study Now Available at MarketReportsOnline.com 2Health News:Pharma Clinical Trials Market in China: Authorities for Drug New Study Now Available at MarketReportsOnline.com 3Health News:Pharma Clinical Trials Market in China: Authorities for Drug New Study Now Available at MarketReportsOnline.com 4
... Reporter , WEDNESDAY, July 20 (HealthDay News) -- Some ... unexplained breathing problems that may be related to exposure ... disorders are emerging as a major consequence of service ... King, an assistant professor of pulmonary and critical care ...
... By Maureen Salamon HealthDay Reporter , ... both cause red, scaly skin rashes, but the similarities ... And now, examining patients suffering from both ... out the opposing immune system responses that prompt skin ...
... scientists have developed a gene-based test to distinguish harmless ... help some patients avoid needless surgery to remove the ... published in the July 20 issue of Science ... cysts are identified in more than a million patients ...
... July 20 (HealthDay News) -- The number of surgical errors ... study finds. In reviewing adverse events and close calls ... in the July 15 issue of the Archives of ... greater emphasis on safety, as well as improved training and ...
... Nev. Caffeine reduces muscle activity in the Fallopian tubes ... "Our experiments were conducted in mice, but this finding goes ... reduce a woman,s chance of becoming pregnant," says Sean Ward, ... Nevada School of Medicine, who conducted the study. ...
... The American Society for Radiation Oncology (ASTRO) has ... Junior Faculty Career Research Training Award and the ... Winners were selected by ASTRO,s Research Evaluation Committee. ... is awarded to stimulate interest in radiation research ...
Cached Medicine News:Health News:Breathing Problems Strike Soldiers Returning From Iraq 2Health News:Scientists Close in on Origins of Psoriasis, Eczema 2Health News:Scientists Close in on Origins of Psoriasis, Eczema 3Health News:Benign or cancerous? Gene test predicts cancer potential in pancreatic cysts 2Health News:Benign or cancerous? Gene test predicts cancer potential in pancreatic cysts 3Health News:Fewer Surgical Errors Reported at VA Medical Facilities 2Health News:Nevada School of Medicine researcher finds caffeine consumption, female infertility link 2
(Date:7/29/2014)... and TORONTO ... Acquisitions Corporation (OTCBB: ESAQ), an emerging pharmaceutical ... development of improved novel formulations and alternative ... announces expansion of its pharmaceutical development implementing ... direction includes large molecule drugs that will address ...
(Date:7/29/2014)... , July 29, 2014  Based on ... systems (PERS) market, Frost & Sullivan recognizes MobileHelp ... Award for Price Performance Value Leadership. MobileHelp,s leadership ... captures expectations for tech progression in personal emergency ... for these solutions. MobileHelp is at ...
(Date:7/29/2014)... Medical Corporation (Apex, TWSE: 4106), a leading player in the ... is appealing the judgment of the Regional Court of ... that found the headgear of certain mask models infringe a ... against various ResMed patents in major countries. Apex further reiterates ... ResMed filed the lawsuit with the Regional ...
Breaking Medicine Technology:EastGate Acquisitions Announces Expansion of its Pharmaceutical Developments Implementing its Sub-Micron Platform Technology 2EastGate Acquisitions Announces Expansion of its Pharmaceutical Developments Implementing its Sub-Micron Platform Technology 3EastGate Acquisitions Announces Expansion of its Pharmaceutical Developments Implementing its Sub-Micron Platform Technology 4Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 2Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 3Apex Continues Fighting Against Patents to Free Up Competition 2
... 2011 Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: ... and commercialization of products for central nervous system disorders, ... one of Israel,s leading private biotech, pharmaceutical and medical ... Israel. "We are excited to reach this ...
... Cell Therapeutics, Inc. ("CTI") (NASDAQ: CTIC ... that final results from the phase II OPAL study ... acute myeloid leukemia (AML) were presented by Jorge Cortes, ... Center during the Acute Myeloid Leukemia - Therapy, excluding ...
Cached Medicine Technology:Vanda Pharmaceuticals Enters into an Exclusive License Agreement with Megapharm Ltd. for Commercialization of Fanapt™ in Israel 2Vanda Pharmaceuticals Enters into an Exclusive License Agreement with Megapharm Ltd. for Commercialization of Fanapt™ in Israel 3Vanda Pharmaceuticals Enters into an Exclusive License Agreement with Megapharm Ltd. for Commercialization of Fanapt™ in Israel 4Final OPAL Phase II Results of Tosedostat Demonstrate Significant Response Rates in Elderly Patients with Treatment Refractory or Relapsed Primary or Secondary Acute Myeloid Leukemia (AML) 2Final OPAL Phase II Results of Tosedostat Demonstrate Significant Response Rates in Elderly Patients with Treatment Refractory or Relapsed Primary or Secondary Acute Myeloid Leukemia (AML) 3Final OPAL Phase II Results of Tosedostat Demonstrate Significant Response Rates in Elderly Patients with Treatment Refractory or Relapsed Primary or Secondary Acute Myeloid Leukemia (AML) 4
... and removal in the urinary tract. The nitinol ... shape following extreme torsion. The unique tipless design ... basket to open at the base of the ... reduces the likelihood of mucosal damage and perforation. ...
... Used for soft-tissue ... limited to paravaginal repairs, ... or rectocele. Surgisis® ES ... enhanced strength for intraoperative ...
... Used for temporary suprapubic urinary diversion ... puncture the bladder. The access sheath is ... Once the catheter is introduced, the access ... low-profile catheter support is included for external ...
... and a FAM-labeled probe targeting the VP1 gene ... ASR contains primers and a Texas Red-labeled probe ... an instrument that can detect FAM and Texas ... Analyte Specific Reagent* (ASR) program is comprised of ...
Medicine Products: