Navigation Links
Grant helps UT Southwestern researcher study causes of preterm birth
Date:4/5/2011

DALLAS April 7, 2011 A UT Southwestern Medical Center gynecologist is one of five researchers nationwide selected to receive a $600,000 Burroughs Wellcome Fund grant to investigate the biological mechanisms and causes of premature birth.

Dr. Mala S. Mahendroo, associate professor of obstetrics and gynecology in the Cecil H. and Ida Green Center for Reproductive Biological Sciences, will use the support to develop a second harmonic generation imaging (SHG) endoscope to be used in vivo in animals, and eventually in women, to assess premature collagen changes that precede preterm birth.

"This grant will allow us to do molecular studies on the cervix and develop a clinical tool to identify women at risk for preterm birth," Dr. Mahendroo said.

According to medical experts, nearly 13 percent of births in the U.S. more than one-half million annually are preterm. Rates are even higher in African-American and obese populations. While a normal term delivery occurs at around 40 weeks, more than 70 percent of premature babies are born between 34 and 36 weeks gestation.

The causes of preterm labor are not fully understood. Premature babies are at increased risk for newborn health complications such as breathing problems, underdeveloped organs and even death.

"Biological research is done in small steps," said John Burris, president of the Burroughs Wellcome Fund. "It is our hope that by funding creative, innovative research, new therapies will be developed."

An independent private foundation, the Burroughs Wellcome Fund helps advance the medical sciences by supporting research and other scientific and educational activities. Its board's general strategy is to help scientists early in their careers develop as independent investigators, and to support scientists who are working in, or entering, biomedical science fields that are poised for significant advance but currently undervalued and underfunded.

Dr. Mahendroo's laboratory work focuses on the molecular processes that bring about cervical ripening and remodeling from a closed rigid structure to one that expands enough to allow the passage of a full-term baby. She and colleagues hope to understand the molecular events that regulate the change in collagen structure in order to develop therapies that prevent preterm labor.

"Changes in cervical collagen organization begin relatively early in pregnancy and are incremental and progressive," she said. "SHG imaging allows us to visualize and distinguish these microscopic collagen changes."

Dr. Mahendroo joined the UT Southwestern faculty in 2000. A Texas A&M graduate, she earned her doctorate in biochemistry and molecular biology from UT Southwestern, where she also completed a postdoctoral fellowship in molecular genetics.


'/>"/>

Contact: Robin Russell
robin.russell@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Related medicine news :

1. NACDD Receives Two-Year Grant From Merck & Co., Inc. to Improve Diabetes Education
2. Kaiser Permanente Approves $170 Million in Community Benefit Grants in 2009
3. Autism Science Foundation Offers IMFAR Grants to Autism Stakeholders
4. Perrigo Granted Summary Judgment of Non-Infringement in Mucinex(R) Case
5. US21, Inc. is Granted a Wholesale Distributor Permit from the Commonwealth of Virginia Board of Pharmacy
6. San Diego State University and BIOCOM Institute Receive $4.95 Million Grant: The BRIDGE Project, Linking Education to Employment in San Diegos Life Sciences Industry
7. NIH grants to Childrens Hospital will advance novel stem cell treatments for blood disorders
8. Special Olympics Georgia Receives Grant from The Home Depot Foundation
9. NIH grant will create behavioral health registry for pediatric inflammatory bowel disease
10. San Diego Unified School District Awarded Silent Hero Grant From got breakfast?(R) Foundation
11. Congressional Staff Briefing, Wed., Feb. 24 on Mental Health, Medicaid & Block Grants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... ... April 24, 2017 , ... ... prescription opioid overdose deaths now claim the lives of 62 Americans each day.(1) ... filings against drug manufacturers, distributors, pharmacies and prescribers by more than half.(2) ...
(Date:4/24/2017)... , ... April 24, 2017 , ... ... designed to recognize elevated anxiety levels in people with addiction who are served ... Smart Patch, a biosensing wearable device that monitors heart and breath rates to ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... ... health of individuals with HIV because it is not known to have significant ... have favorable effects to both lower cholesterol levels and dampen inflammation in the ...
(Date:4/24/2017)... ... ... Come to PAINWeekEnd (PWE) Tampa on May 20 and 21, at the ... 2-day program. , An attendee at a recent PAINWeekEnd said, "Very helpful, wish ... course entitled Ain't Misbehavin': Decreasing and Managing Pain Patient Aberrant Behavior, presented by Dr. ...
(Date:4/24/2017)... FOREST KNOLLS, Calif. (PRWEB) , ... April 24, 2017 , ... ... and health topics, but she has not found any of them to be very ... weekly actions to slowly and easily make changes in their health. It prompted her ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017  Vivify Health, the pioneer ... has been awarded a very significant patent for the ... to continual care via digital health.  This landmark patent ... property and further secures Vivify,s position as the leader ... 2009, was the first company to apply consumer mobile ...
(Date:4/20/2017)... April 20, 2017 Research and Markets has ... Innovation Driven by Rapidly Expanding Injectables Market and Increasing Usage of ... ... delivery technologies will rise from USD 20 Billion in 2015 to ... Drug Delivery Technologies - Innovation Driven by Rapidly Expanding Injectables Market ...
(Date:4/20/2017)... Research and Markets has announced the ... Application Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies ... ... was valued at US$ 7,167.6 Mn in 2015, and is ... a CAGR of 5.6% from 2016 to 2024. ...
Breaking Medicine Technology: