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Grandmother's cigarette habit could be the cause of grandchild's asthma
Date:3/4/2013

involved in the transmission of epigenetic human diseases," Dr. Torday said. "The transmission of the asthma to the second generation and its prevention by a specifically-targeted molecular intervention are the first unequivocal demonstrations of multi-generational transmission of an epigenetically-mediated effect on the offspring."

Dr. Rehan, who has conducted multiple studies on nicotine's effects, noted that asthma rates are growing in the U.S. and around the world. World-wide, approximately 250,000,000 women smoke daily. Twelve percent of women in the U.S. continue to smoke during pregnancy, resulting in the birth of at least 400,000 smoke-exposed infants per year in the U.S. alone

"Asthma is the most common chronic disease of childhood, resulting in a significant impact on the lives of children and driving up medical costs for all," Dr. Rehan said. "While many factors contribute to asthma, smoking during pregnancy is a well-established one and one that can be avoided. Eliminating smoking during pregnancy would significantly reduce the prevalence of childhood asthma for this generation and for future generations."


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Contact: Laura Mecoy
lmecoy@labiomed.org
310-546-5860
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)
Source:Eurekalert

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