Navigation Links
Gout Drug Shows Promise
Date:11/9/2007

Injected rilonacept effective in easing pain, study finds

FRIDAY, Nov. 9 (HealthDay News) -- A drug called rilonacept (IL-1 Trap) may reduce disease activity and pain in patients with chronic active gout.

That's according to a non-randomized, single-blind, placebo-controlled study of 10 patients, average age 62, who had gout for an average of 13 years.

The study was led by Dr. Robert Terkeltaub of the VA Medical Center and University of California, San Diego.

Gout is a painful and potentially disabling form of arthritis. Initial symptoms usually consist of painful swelling in single joints, especially the big toe.

Rilonacept -- a new drug being tested in the treatment of inflammatory conditions -- prevents a protein called interleukin-1 from attaching to cell surface receptors and causing disease flare-up.

The patients in the study received twice-weekly injections of a placebo, followed by six weekly injections of rilonacept. In the second through eighth week of treatment, 70 percent of the patients had at least a 50 percent improvement in pain, and 60 percent of the patients had at least a 75 percent improvement in pain. There was no improvement in pain when the patients received the placebo.

By the eighth week of treatment, there was a 59 percent decrease in inflammation levels.

The study was to presented Nov. 9 at the American College of Rheumatology meeting in Boston.

More information

The American Academy of Family Physicians has more about gout.



-- Robert Preidt



SOURCE: American College of Rheumatology, news release, Nov. 7, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. New study shows promise in reducing surgical risks associated with surgical bleeding
2. New research shows how chronic stress worsens neurodegenerative disease course
3. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
4. Circulating fats kill transplanted pancreas cells, study shows
5. New Heart Pump Shows Promise in Trial
6. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
7. New Survey Shows Americans are Still Concerned About Food Safety, Yet Still Not Smart About What They Like to Eat
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
10. Avocados may help prevent oral cancer, OSU study shows
11. New Poll Shows Public Distrusts Flawed Healthcare Approach Favored by Governor and Speaker in AB 8
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/25/2017)... ... September 25, 2017 , ... International Water Advocate Sharon Kleyne ... Hour Power of Water, Global Climate Change and Your Health on VoiceAmerica sponsored ... a once-every-four-years series of events to a personal, daily Health Olympics. “Wouldn’t it ...
(Date:9/25/2017)... ... September 25, 2017 , ... ... and efficiency. The principle of First-Defect-Stop for laboratory weighing is designed ... have the chance to have negative consequences on downstream processes. , If a ...
(Date:9/25/2017)... ... September 25, 2017 , ... Bobbie Horowitz was hardly ... and multiple health issues. As a cabaret and theater producer, Horowitz would manage to ... source of transportation in New York City, so she had to take a cab ...
(Date:9/25/2017)... ... , ... METTLER TOLEDO is pleased to host the 3rd Annual Metrology ... symposium will feature speakers from North American National Measurement Institutes (NMI) with a purpose ... planning for the future of the modern lab. , The event is not just ...
(Date:9/25/2017)... ... September 25, 2017 , ... ... research, today announces that 30 of its domain experts will present on ... at upcoming industry conferences and webinars. Drawing on broad and deep industry ...
Breaking Medicine News(10 mins):
(Date:8/31/2017)... NEW YORK , Aug. 31, 2017 ... the industry,s must-read guide to the latest innovations happening ... the first industry publication to focus on providing a ... advancements. Ultimately, the issue covers the most innovative companies, ... year. "Everyone in ...
(Date:8/29/2017)... Aug. 29, 2017 In a move that ... regulatory compliance for veterinary practices of all sizes, Cubex ... partnership that makes TITAN,s expertise in physical security, drug ... Cubex,s clients nationally. ... handling controlled substances is at risk today," said TITAN ...
(Date:8/28/2017)... Aug. 28, 2017   Aesculight ®, a division of LightScalpel ... surgical lasers. Built on over 20 years of American veterinary laser surgery ... and Exclusive VetScalpel®Features and Enhancements ... DVM, is excising a tumor with his new VetScalpel laser. Dr. Duclos ... WA. ...
Breaking Medicine Technology: