Navigation Links
Gout Drug Shows Promise
Date:11/9/2007

Injected rilonacept effective in easing pain, study finds

FRIDAY, Nov. 9 (HealthDay News) -- A drug called rilonacept (IL-1 Trap) may reduce disease activity and pain in patients with chronic active gout.

That's according to a non-randomized, single-blind, placebo-controlled study of 10 patients, average age 62, who had gout for an average of 13 years.

The study was led by Dr. Robert Terkeltaub of the VA Medical Center and University of California, San Diego.

Gout is a painful and potentially disabling form of arthritis. Initial symptoms usually consist of painful swelling in single joints, especially the big toe.

Rilonacept -- a new drug being tested in the treatment of inflammatory conditions -- prevents a protein called interleukin-1 from attaching to cell surface receptors and causing disease flare-up.

The patients in the study received twice-weekly injections of a placebo, followed by six weekly injections of rilonacept. In the second through eighth week of treatment, 70 percent of the patients had at least a 50 percent improvement in pain, and 60 percent of the patients had at least a 75 percent improvement in pain. There was no improvement in pain when the patients received the placebo.

By the eighth week of treatment, there was a 59 percent decrease in inflammation levels.

The study was to presented Nov. 9 at the American College of Rheumatology meeting in Boston.

More information

The American Academy of Family Physicians has more about gout.



-- Robert Preidt



SOURCE: American College of Rheumatology, news release, Nov. 7, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. New study shows promise in reducing surgical risks associated with surgical bleeding
2. New research shows how chronic stress worsens neurodegenerative disease course
3. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
4. Circulating fats kill transplanted pancreas cells, study shows
5. New Heart Pump Shows Promise in Trial
6. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
7. New Survey Shows Americans are Still Concerned About Food Safety, Yet Still Not Smart About What They Like to Eat
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
10. Avocados may help prevent oral cancer, OSU study shows
11. New Poll Shows Public Distrusts Flawed Healthcare Approach Favored by Governor and Speaker in AB 8
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Ill. (PRWEB) , ... October ... ... Edwardsville School of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer ... healthcare professionals on guideline updates for the primary prevention of cardiovascular diseases ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional women, ... towards gender equality at their inaugural Summit in New York City in June. The ... social audience of over 3 million. To watch the Mobilize Women video, click ...
(Date:10/13/2017)... ... 2017 , ... “The Journey: From the Mountains to the Mission Field”: the ... in the Philippines. “The Journey: From the Mountains to the Mission Field” is the ... She has taught all ages and currently teaches a class of ladies at her ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company ... of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every ... meet the highest standard. , These products are also: Gluten Free, Non-GMO, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the Los ... article to the newly revamped Cosmetic Town journal section, featuring articles ... procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi says ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Mich. , Oct. 2, 2017 Diplomat ... 8th Day Software and Consulting, LLC , and ... 8th Day Software, based in Tennessee ... LLC. 8th Day expands EnvoyHealth,s service offerings for health ... development. "In an ...
(Date:10/2/2017)... announces the European launch of their new low volume, high throughput ... Cambridge, U.K on October 4th. The new ... unprecedented speed and sensitivity while using far less sample volume through ... ... ...
(Date:9/28/2017)... Sept. 28, 2017 Cohen Veterans Bioscience and ... use of wearable and home sensors for real-time monitoring ... Signal Foundation, a nonprofit organization focused on disruptive health ... an affordable analytical system to record and integrate behavioral, ... ...
Breaking Medicine Technology: