Navigation Links
Gout Drug Shows Promise
Date:11/9/2007

Injected rilonacept effective in easing pain, study finds

FRIDAY, Nov. 9 (HealthDay News) -- A drug called rilonacept (IL-1 Trap) may reduce disease activity and pain in patients with chronic active gout.

That's according to a non-randomized, single-blind, placebo-controlled study of 10 patients, average age 62, who had gout for an average of 13 years.

The study was led by Dr. Robert Terkeltaub of the VA Medical Center and University of California, San Diego.

Gout is a painful and potentially disabling form of arthritis. Initial symptoms usually consist of painful swelling in single joints, especially the big toe.

Rilonacept -- a new drug being tested in the treatment of inflammatory conditions -- prevents a protein called interleukin-1 from attaching to cell surface receptors and causing disease flare-up.

The patients in the study received twice-weekly injections of a placebo, followed by six weekly injections of rilonacept. In the second through eighth week of treatment, 70 percent of the patients had at least a 50 percent improvement in pain, and 60 percent of the patients had at least a 75 percent improvement in pain. There was no improvement in pain when the patients received the placebo.

By the eighth week of treatment, there was a 59 percent decrease in inflammation levels.

The study was to presented Nov. 9 at the American College of Rheumatology meeting in Boston.

More information

The American Academy of Family Physicians has more about gout.



-- Robert Preidt



SOURCE: American College of Rheumatology, news release, Nov. 7, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. New study shows promise in reducing surgical risks associated with surgical bleeding
2. New research shows how chronic stress worsens neurodegenerative disease course
3. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
4. Circulating fats kill transplanted pancreas cells, study shows
5. New Heart Pump Shows Promise in Trial
6. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
7. New Survey Shows Americans are Still Concerned About Food Safety, Yet Still Not Smart About What They Like to Eat
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
10. Avocados may help prevent oral cancer, OSU study shows
11. New Poll Shows Public Distrusts Flawed Healthcare Approach Favored by Governor and Speaker in AB 8
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... Hills, CA (PRWEB) , ... May 04, 2016 , ... ... care that ex-supermodel Janice Dickinson needed following breast cancer surgery. In March 2016, the ... situ, a type of breast cancer that occurs in the milk ducts, according to ...
(Date:5/4/2016)... , ... May 04, 2016 , ... ... medical coding, billing and compliance. In upcoming months, AudioEducator has lined up some ... Every conference is designed to give complete compliance know-how and practical, easy-to-apply advice. ...
(Date:5/4/2016)... ... May 03, 2016 – (PRWEB) May ... and child products, today revealed the non-toxic benefits of its Tutti ... deal with teething pain is just part of the story. These ... are BPA-, PVC-, and phthalate-free. , “Many baby toys contain ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... they acquired Pocono Sterilizer, an equipment sterilization service and sales company located in ... provides medical and research-related equipment and asset management services to the medical and ...
(Date:5/4/2016)... Clara, California (PRWEB) , ... May 04, 2016 ... ... organized by United Scientific Group is scheduled on July 25-27, 2016 at Las ... and other health care professionals from educational institutes and research organizations across the ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... TUSTIN, Calif. , May 3, 2016 /PRNewswire/ ... science teaching tool that shows how a cleanroom ... for classroom discussions about science and technology. ... Manager said, "As a technology company, SSF enthusiastically ... program to help educators foster the next generation ...
(Date:5/3/2016)... May 3, 2016 ... dass sie einen entscheidenden Meilenstein durch diese ... Aufruf zum Handeln, um Patientenresultate  bei Verdauungs- ... zu Fortschritten im Verständnis der Hepatischen Enzephalopathie ... Bewusstsein für Hepatische Enzephalopathie in der Öffentlichkeit ...
(Date:5/2/2016)... , May 2, 2016  While nearly three-quarters ... osteoporosis can have on their health, only about half ... according to the results of a new survey announced ... mark the start of National Osteoporosis Month, Hologic is ... which affects nearly 56 million Americans. Osteoporosis ...
Breaking Medicine Technology: