Navigation Links
Gout Drug Shows Promise

Injected rilonacept effective in easing pain, study finds

FRIDAY, Nov. 9 (HealthDay News) -- A drug called rilonacept (IL-1 Trap) may reduce disease activity and pain in patients with chronic active gout.

That's according to a non-randomized, single-blind, placebo-controlled study of 10 patients, average age 62, who had gout for an average of 13 years.

The study was led by Dr. Robert Terkeltaub of the VA Medical Center and University of California, San Diego.

Gout is a painful and potentially disabling form of arthritis. Initial symptoms usually consist of painful swelling in single joints, especially the big toe.

Rilonacept -- a new drug being tested in the treatment of inflammatory conditions -- prevents a protein called interleukin-1 from attaching to cell surface receptors and causing disease flare-up.

The patients in the study received twice-weekly injections of a placebo, followed by six weekly injections of rilonacept. In the second through eighth week of treatment, 70 percent of the patients had at least a 50 percent improvement in pain, and 60 percent of the patients had at least a 75 percent improvement in pain. There was no improvement in pain when the patients received the placebo.

By the eighth week of treatment, there was a 59 percent decrease in inflammation levels.

The study was to presented Nov. 9 at the American College of Rheumatology meeting in Boston.

More information

The American Academy of Family Physicians has more about gout.

-- Robert Preidt

SOURCE: American College of Rheumatology, news release, Nov. 7, 2007

Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. New study shows promise in reducing surgical risks associated with surgical bleeding
2. New research shows how chronic stress worsens neurodegenerative disease course
3. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
4. Circulating fats kill transplanted pancreas cells, study shows
5. New Heart Pump Shows Promise in Trial
6. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
7. New Survey Shows Americans are Still Concerned About Food Safety, Yet Still Not Smart About What They Like to Eat
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
10. Avocados may help prevent oral cancer, OSU study shows
11. New Poll Shows Public Distrusts Flawed Healthcare Approach Favored by Governor and Speaker in AB 8
Post Your Comments:
(Date:12/1/2015)... ... 01, 2015 , ... Dr. Paul Vitenas, one of the top cosmetic ... MedEsthetics magazine as the Best Single Physician Practice in the nation. Dr. Vitenas and ... physicians honored by the industry publication. , Dr. Vitenas said he was very ...
(Date:12/1/2015)... ... December 01, 2015 , ... CloudLIMS today ... Golden Bridge Business Awards under the New Products and Services category for its ... sample management software that helps labs organize data and track samples ...
(Date:12/1/2015)... ... December 01, 2015 , ... For many X-rays taken ... for accurate interpretation by the radiologist. The marking utensils are so small, however, ... has found a way to alleviate this problem. , He developed the patent-pending ...
(Date:12/1/2015)... ... December 01, 2015 , ... McLean, VA., December 1, ... fixed price per sprint agile development contract to support the National Geospatial-Intelligence Agency's ... years, provides software engineering, infrastructure, as well as operations and sustainment support to ...
(Date:12/1/2015)... ... December 01, 2015 , ... PartnerTech , ... membership and leadership since 2008. Gary Bruce, President of PartnerTech North America, currently ... spent a significant amount of time in Sweden since joining PartnerTech based in ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... , Dec. 1, 2015 Assurex Health, ... GeneSight® Psychotropic test giving healthcare providers an expanded range ... for patients suffering from depression, anxiety, bipolar disorder, ... health conditions. i .   ... With the addition of two new drug ...
(Date:12/1/2015)... Dec. 1, 2015  AccuTEC Blades, a leader ... corporate logo and brand identity program. The new ... engineering of bladed products where "the edge makes ... --> Serving manufacturers and distributors of ... glass equipment, AccuTEC,s product lines include those acquired ...
(Date:12/1/2015)... -- Six months of adjunctive metformin therapy does not improve glycemic ... new research from T1D Exchange and funded by ... effect on measures of obesity, including weight and BMI. The ... of the American Medical Association , are from the largest ... overweight and obese adolescents with type 1 diabetes. ...
Breaking Medicine Technology: