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Gourmetceuticals Presents Findings on Science You Can Eat at Experimental Biology 2008
Date:4/8/2008

Poster presentations highlight findings related to two botanical functional

food ingredients, GLPH-1(TM) and PPL-240(TM)

BIG HORN, Wyo., April 8, 2008 /PRNewswire/ -- Gourmetceuticals, LLC, a company that markets scientifically validated and organically derived ingredients for use in foods and beverages, today announced the findings from four studies that evaluate GLPH-1(TM), an immune booster, and PPL-240(TM), a photoprotective antioxidant, at Experimental Biology 2008 in San Diego. Functional foods are foods and beverages with claimed health benefits based on scientific evidence.

"The functional food market has grown to be a $25 billion industry and consumers should feel confident that the functional ingredients in foods are safe and an effective way to support health and well being," commented Garrett Lindemann, Ph.D., CEO and CSO of Gourmetceuticals. "We are an organization founded on science and are in the early process of transitioning to a commercial organization. It is our commitment to continue ongoing scientific validation of our ingredients."

Both PPL-240 and GLPH-1 have been investigated in more than 20 clinical and pre-clinical studies. The company plans to integrate both ingredients into scientifically validated healthful foods and drinks through strategic co-development deals with key food manufacturers.

PPL-240(TM) -- photoprotective antioxidant

Findings from Polypodium leucotomos extract, PPL-240, prevents solar-induced DNA damage in human peripheral blood mononuclear cells were presented April 6 (poster number: A414) and analyzed the effect of PPL-240 on the cellular damage of human peripheral blood mononuclear cells (PBMC) induced by solar radiation. Cells were incubated for two hours in either presence or absence of PPL-240. The study found that cells in the presence of PPL-240 experienced a reduction in mitogen-induced cell death (18.76% vs. 29.64% respectively).

"We found that PPL-240 reduced cell death caused by sun exposure," commented Dr. Eduardo Reyes, of the Laboratory of Immune System Diseases and Oncology at the National Biotechnology Center Associated Unit Department of Medicine, University of Alcala, Madrid, Spain. "Several previously completed and reported studies of PPL-240 in humans demonstrate its photoprotective properties."

GLPH-1(TM) -- immune booster

Findings from three studies with GLPH-1 were presented on April 8 that evaluated GLPH-1 compared to a common antibiotic, and two on its mechanism of action and pathway.

Experimental animal model study of diet supplementation with phosphorylated alpha glucomannan polysaccharide, GLPH-1 (poster number: C304) evaluated the efficacy of GLPH-1 as an alternative to bacitracin (BMD 60), a common antibiotic, fed to broiler chickens. During the course of 345 days, GLPH-1, fed at 1 mg/kg body weight, was compared to bacitracin at a sub-therapeutic level and an additive free diet in a production setting. Food intake per pen and individual body weights were collected. The study found that GLPH-1 was a growth promoting additive resulting in body weight gain (2.87% and 3.10%) with no associated increase in mortality. However, chickens fed with BMD 60 suffered a reduced accumulated survival and diminished body weight (-3.72% and -4.03%).

"The practice of supplementing animal diets with antibiotics is increasingly problematic as sub-therapeutic doses of antibiotics are linked to antibiotic-resistant strains of bacteria in humans," commented Dr. Lindemann. "The World Health Organization has recommended that antibiotics not be used for growth promotion in feed animals. GLPH-1 may be a safe and effective, natural alternative."

The second study The presence of an alpha glucomannan polysaccharide, GLPH-1, (IF-S) activates NFkB and p38 in hMDDC (poster number: A466) found that GLPH-1 activates white blood cells, an important part of the body's immune system, and that it binds to pathogen receptor sites to reduce uptake of infectious and disease causing agents.

The third study IF-S, a phosphorylated alpha glucomannan polysaccharide, GLPH-1, induces functional human dendritic cell maturation (poster number: A465) found that GLPH-1 may be a useful reagent for regulating immune response against viruses and bacteria.

About Functional Foods

Functional foods are foods and beverages with claimed health benefits based on scientific evidence. The field of functional foods is an emerging field in the food science industry and is composed of the foods that contain scientifically validated ingredients that provide a health benefit above the benefit of the food itself. The market is growing exponentially with a projected growth from $25 billion in 2006 to $39 billion by 2011.

About Gourmetceuticals

Gourmetceuticals, LLC is a research-based culinary technology company that markets organically derived and scientifically tested ingredients for use in foods and beverages. Its ingredients, GLPH-1(TM) and PPL-240(TM), can transform human and veterinary products into gourmet functional foods and are FDA approved for human and animal consumption, GRAS affirmed, Kosher and meet current Good Manufacturing Practices (cGMP) as outlined by the FDA. GLPH-1 is a polysaccharide extract from botanical yeast that promotes immune health and PPL-240 is an antioxidant derived from a South American fern that has been shown clinically to reduce damage from UVA and UVB rays. Both ingredients have been subject to more than 20 clinical trials that evaluated and supported their safety and effectiveness in humans and animals. For more information, visit the Company Web site at http://www.gourmetceuticals.com.


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