Navigation Links
Glowing Substance Lights Up Cancer in Mice
Date:12/8/2008

Fluorescent compound sticks to diseased cells, making them easier to spot, study says

MONDAY, Dec. 8 (HealthDay News) -- A substance that glows and sticks to viable cancer cells, making them easy for doctors to spot, has been successfully tested in mice, researchers report.

The man-made compound, a combination of the breast cancer drug Herceptin and a fluorescent molecule called BODIPY, binds to the HER2 protein contained on the surface of some breast cancer cells. It only glows, or fluoresces, when inside living cells -- an improvement from most fluorescent imaging compounds that always glow and make it difficult for doctors to tell viable tumor cells from normal tissue or dead or damaged tumor cells.

The findings, made by researchers at the U.S. National Cancer Institute, were published online Dec. 7 in Nature Medicine.

"Imaging compounds designed by our concept may have applications in the clinic," lead researcher Dr. Hisataka Kobayashi of the Molecular Imaging Program of NCI's Center for Cancer Research, said in a news release issued by the institute. "These compounds may allow clinicians to monitor a patient's response to cancer therapy by allowing them to visualize whether a drug hits its target and whether hitting the target leads to shrinkage of the tumor. With additional research and extensive testing in humans, these compounds may also be adapted for use in endoscopy procedures and for use as a surgical aid to improve removal of tumors."

The compound should be able to be engineered to target specific types of cancer cells.

"Our design concept is very versatile and can be used to detect many types of cancer," Kobayashi said. "Unlike other activatable fluorescent compounds, our compound consists of a targeting agent and a fluorescing agent that act independently. We can target the fluorescing agent to different types of cancer cells by using any antibody or molecule th
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Mailman School of Public Health study examines link between racial discrimination and substance use
2. National Quality Forum Issues First Consensus Standards for the Treatment of Substance Use Conditions
3. Inflammatory Substance May Boost Eye Trouble
4. Research examines connection between substance abuse and violence
5. L.A. Author, TV Personality and Substance Abuse Specialist Discusses Struggle to Break Bad-girl Syndrome Oct. 26-28 in Baltimore
6. Gauging parent knowledge about teens substance use
7. Substance abuse practitioners ask what is recovery?
8. One-Third of Popular Songs Refer to Substance Abuse
9. AAPM statement on DEA ruling allowing multiple prescriptions for controlled substances
10. Cardinal Health Receives DEA Order to Temporarily Cease Distribution of Controlled Substances from Auburn, Wash. Facility
11. PSU $5.7 million grant to help families and youth avoid substance abuse, behavior problems
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Glowing Substance Lights Up Cancer  in Mice
(Date:1/22/2015)... 23, 2015 AngelWeddingDress, the premier women’s ... maternity wedding dresses. View website of AngelWeddingDress.com ... for maternity wedding dresses online for a bridal party. ... high quality for them. Its maternity wedding dresses are ...
(Date:1/22/2015)... 2015 Juvent Sports ( http://www.juventsports.com ) ... PGA Merchandise Show to bestow a Juvent Sports Achievement ... golfer, Arlene McKitrick. The award commemorated and congratulated McKitrick ... win. She won her first amateur tournament in 1979 ...
(Date:1/22/2015)... New York, New York (PRWEB) January 22, 2015 ... filed after Fresenius Medical Care recalled its GranuFlo ... the federal multidistrict litigation underway in U.S. District Court, ... an Order dated January 20th, the Court has remanded ...
(Date:1/22/2015)... 2015 For over 20 years, Dr. David Cruz ... Vista area has treated just about every type of injury ... And for those same twenty-plus years, the team at ... injuries with the best possible doctor. With the combined ...
(Date:1/22/2015)... 22, 2015 Joan Lunden, award-winning American ... at the upcoming 32nd Annual Miami Breast Cancer ... Education Resource®, LLC (PER®) , shares that “a fast-growing, ... undetected if she had not followed up her clean ...
Breaking Medicine News(10 mins):Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6
... behavior in juvenile justice teens has yielded a surprising side ... pregnancy, according to a new study out this week. ... at Oregon State University, and Leslie Leve and Patricia Chamberlain ... which will be published in the April edition of the ...
... ... non-scientific claims have consumers seeking supplements and products based on scientific evidence, not marketing ... the new standard in consumer awareness and trust. , ... Anaheim, CA (PRWEB) June 1, 2009 -- Creatine ...
... ... offer training to individuals interested in pursing careers in medical transcription and medical coding ... ... has partnered with Clinton Community College in Plattsburgh, N.Y. to offer training to individuals ...
... MD (June 1, 2009) Obesity is an independent ... presence of additional risk factors further increases the likelihood ... study in Clinical Gastroenterology and Hepatology , the ... , Obesity has become an epidemic in the present ...
... (Nasdaq: MYL ) today announced that its ... delisting offer for the publicly held shares of Matrix ... manufacturer in which Mylan acquired a controlling interest in ... per share, which was established by the reverse book ...
... Doctor George Tiller is an abhorrent act of violence, and ... tragic moment. Federal law enforcement is coordinating with local ... crime, and I have directed the United States Marshals Service ... the nation. The Department of Justice will work to ...
Cached Medicine News:Health News:Intervention reduces delinquent teenage pregancy rates 2Health News:Intervention reduces delinquent teenage pregancy rates 3Health News:Max Muscle Sports Nutrition Releases The Truth About Creatine 2Health News:Max Muscle Sports Nutrition Releases The Truth About Creatine 3Health News:Max Muscle Sports Nutrition Releases The Truth About Creatine 4Health News:Career Step Partners with Clinton Community College to Help Students Gain Careers in Secure Healthcare Industry 2Health News:Obesity predicts inadequate bowel prep at colonoscopy 2Health News:Mylan Announces Successful Matrix Delisting Offer 2
(Date:1/23/2015)... , Jan. 23, 2015  Now available for sale, The ... support that prevents ankle sprains by cushioning the ankle ... fits securely around the outside of any shoe type ... comfort while still offering protection against sprains. With customers ...
(Date:1/23/2015)... 23, 2015  CytoSorbents Corporation (NASDAQ CM: CTSO), a ... cytokine adsorber to reduce deadly inflammation in critically-ill ... $385,642, net of transaction costs, in non-dilutive funding ... Tax Certificate Transfer Program sponsored by the New ...
(Date:1/22/2015)... Jan. 22, 2015  ViewRay™, a privately held medical device ... exclusive distributor agreement with ITOCHU Corporation (Tokyo Stock Exchange ... for the treatment of cancer in Japan ... the world,s first and only MRI-guided radiation therapy system ...
Breaking Medicine Technology:The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2
... Enhanced Durability for Excellent ... working with challenging cases. PT² ... of a linear elastic nitinol ... resilient polymer tip. This provides ...
... Separation System is an enabling ... separate cell populations into multiple ... and density. This flexible laboratory ... depletion, concentration, and washing ...
... is a positive-displacement, continuously ... designed to simplify multiple ... Gilson DistriTip syringes. DistriTips ... with level indicators. Three ...
... are lightweight and balanced for smooth, one-handed ... and comfort, reducing fatigue in even the ... a physician to easily steer the catheter ... just one finger. Reflexion's auto-lock technology keeps ...
Medicine Products: