Navigation Links
GlaxoSmithKline Responds to JAMA Articles
Date:9/11/2007

dia and

comparators (HR 0.96). In all of these analyses, the Avandia and the

Actos hazard ratios (HR 0.82 for Actos in Nissen meta-analysis) do not

suggest an increased risk versus the comparators.

-- No long-term, head-to-head clinical trial data specifically evaluates

cardiovascular risk between Avandia and Actos; however, the

head-to-head data that does exist, and the overwhelming majority of

comparative observational data, show no significant differences in CV

events.

The JAMA article on Avandia is yet another iteration of previously analyzed data, and offers no new information on the safety of Avandia. The suggested increase in heart attack cited comes from a selective re-analyses of previously published and highly selective data from only four of 116 available studies, and reflects a difference of only 11 events in 14,291 patients between Avandia and control. In this limited meta-analysis, in the context of all the other evidence, we believe it is inappropriate for the author to advise doctors to disregard the FDA's advice which is to keep patients who are effectively controlling their diabetes on Avandia. These data have been presented to an expert advisory panel of the FDA, which voted to keep Avandia available to patients -- a vote that reflects the role of this medicine as an important treatment option to help diabetes patients control their blood sugar.

The conclusions of these meta-analyses conflict with the wealth of accumulated data on Avandia -- including 116 clinical trials in more than 52,000 patients and epidemiological studies of databases in over 1 million patients. Analyzed studies show no difference in the ischemic cardiovascular effects of Avandia versus other oral anti-diabetic medicines, including Actos.

1. Across this extensive data set, the number of heart attacks is small,

and Avandia is shown to have a comparable cardiovascular profile to the<
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. GlaxoSmithKline - Changes Lamictal(R) Label Appearance and Packaging
2. GlaxoSmithKline To Cultivate Non-Smoking Environment
3. GlaxoSmithKline to Supply United States with 8 Million flu vaccine, Fluarix
4. FDA Mislead On Asthma Drug By GlaxoSmithKline
5. GlaxoSmithKline Defends Its Products
6. GlaxoSmithKline launches diabetes and cancer drugs
7. Generic Products Compete With GlaxoSmithKline
8. GlaxoSmithKline Agrees To Settle Paxil Claims For $14 million
9. GlaxoSmithKlines Zofran Helps In Treatment Of Dehydration In Children
10. Ranbaxy Acquires Glaxosmithklines Generic Unit in Spain
11. GlaxoSmithKline’s Epilepsy Drug given the Green Signal by FD
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... Burn injuries increase in the summer as people gather around ... those most vulnerable to these seasonal fire hazards: children. ... burned by putting their hands on the side of cooking ... at Loyola University Medical Center in Maywood, Ill., said in ... you play with fire, you get burned, is true -- ...
(Date:7/12/2014)... York, New York (PRWEB) July 12, 2014 ... continue to move forward in U.S. courts, Bernstein Liebhard ... ties elevated metal ion levels to the failure of ... July 2nd issue of The Journal of Bone & ... had received unilateral Articular Surface Replacement prostheses at least ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Doylestown Hospital ... a variety of men’s health questions. Paddock tackles ... to men, why women live longer than men, and ... Men's Health Made Simple featured on Doylestown Hospital’s ... a hernia at any age. If you notice pain, ...
(Date:7/12/2014)... Praeclarus Press is excited to ... new resource for women in need of lactation support. ... away from their children. Today’s mothers receive very clear ... but often feel unsupported when it comes to balancing ... evidence-based insights, and written by Nancy Mohrbacher, an international ...
(Date:7/12/2014)... July 12, 2014 The largest pure ... is pleased to announce that it will be opening ... new facility will join four Atlanta-based Nova Medical Centers’ ... at 3209 Deans Bridge Road, and will be open ... , “With Nova’s treatment philosophy of rapid return-to-work ...
Breaking Medicine News(10 mins):Health News:Burn Injuries More Common in Summer 2Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 2Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 3Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 4Health News:Ivyland Medical Center’s Dr. Brad Paddock Offers Tips for Men’s Health 2Health News:Praeclarus Press Announces the Release of Working and Breastfeeding Made Simple by Nancy Mohrbacher, A Much Needed Resource For Today's Working Mothers 2Health News:Nova Medical Centers To Open New Facility in Augusta, Georgia 2
... infected with HIV, immediate antiretroviral therapy (ART) appears preferable ... in the Journal of Infectious Diseases and ... early HIV-1 infection remain unproven, the findings support growing ... of the Medical College of Wisconsin in Milwaukee, led ...
... , THURSDAY, Dec. 15 (HealthDay News) -- ... according to a new study. It involved 53 ... by the families of deceased American patients. The pacemakers ... patients. After receiving the pacemakers, all the patients ...
... HealthDay Reporter , THURSDAY, Dec. 15 (HealthDay News) -- ... exercising, but new research suggests that several short intensive workouts ... longer, more regular exercise regimens. The small, new ... -- a total exercise time of 75 minutes a week ...
... 15 (HealthDay News) -- Gay men who live in states ... make fewer doctor visits and have lower health-care costs, a ... at a large Massachusetts health clinic that provides services for ... months after the 2003 legalization of same-sex marriage in Massachusetts, ...
... Dec. 15 (HealthDay News) -- Nearly 20 million Americans who ... a doctor or other general health care provider, which suggests ... such as high blood pressure, diabetes and heart disease, a ... from more than 31,200 adults who took part in the ...
... International Association for the Study of Lung Cancer (IASLC) ... the international lung cancer community on how we should ... initial statement to the National Lung Screening Trial (NLST) ... April and also hosted a CT screening workshop with ...
Cached Medicine News:Health News:Study suggests early ART in recently HIV-infected patients preferable to delayed treatment 2Health News:Donated Pacemakers From U.S. Safely Reused in India: Study 2Health News:Brief, Intense Exercise Lowers Blood Sugar, Small Study Finds 2Health News:Brief, Intense Exercise Lowers Blood Sugar, Small Study Finds 3Health News:Legalized Same-Sex Marriage May Boost Gay Men's Health 2Health News:Dentists Could Fill Gap in Health Care, Study Says 2Health News:IASLC sets up committee to move CT lung cancer strategic screening forward 2
(Date:1/15/2014)... -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument Industry Report, 2013-2015" ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) Benefiting from aging ... China,s orthopedic instrument industry has seen rapid ... from 3.28 billion yuan in 2006 to 9.85 billion ...
(Date:1/15/2014)... Jan. 15, 2014 As health officials across the Midwest ... Meijer pharmacies in Michigan will offer ... patients, enabling Meijer pharmacists to administer tests and, in some ... a physician participating in the study. The ...
(Date:1/15/2014)... Corporation (the "Company") (NASDAQ: CLSN ) today ... to purchase an aggregate of approximately $15 million of ... offering, led by a dedicated health care fund. ... these investors pursuant to which the Company agreed to ...
Breaking Medicine Technology:Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3
... 2011 Omeros Corporation (NASDAQ: OMER ) ... in the Company,s Phase 3 clinical program evaluating OMS302 ... proprietary PharmacoSurgery™ products, is added to standard irrigation solution ... maintain intraoperative mydriasis (pupil dilation) and reduce postoperative pain ...
... YORK, Oct. 11, 2011 Reportlinker.com announces ... available in its catalogue: ... 2016 http://www.reportlinker.com/p0336530/Asia-Pacific-Orthopedic-Devices-Market-Outlook-to-2016.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Orthopedic ... Outlook to 2016 Summary ...
Cached Medicine Technology:Omeros Announces First Patients Treated in Phase 3 Clinical Program Evaluating OMS302 2Omeros Announces First Patients Treated in Phase 3 Clinical Program Evaluating OMS302 3Asia-Pacific Orthopedic Devices Market Outlook to 2016 2Asia-Pacific Orthopedic Devices Market Outlook to 2016 3Asia-Pacific Orthopedic Devices Market Outlook to 2016 4Asia-Pacific Orthopedic Devices Market Outlook to 2016 5Asia-Pacific Orthopedic Devices Market Outlook to 2016 6Asia-Pacific Orthopedic Devices Market Outlook to 2016 7Asia-Pacific Orthopedic Devices Market Outlook to 2016 8Asia-Pacific Orthopedic Devices Market Outlook to 2016 9Asia-Pacific Orthopedic Devices Market Outlook to 2016 10Asia-Pacific Orthopedic Devices Market Outlook to 2016 11Asia-Pacific Orthopedic Devices Market Outlook to 2016 12Asia-Pacific Orthopedic Devices Market Outlook to 2016 13Asia-Pacific Orthopedic Devices Market Outlook to 2016 14Asia-Pacific Orthopedic Devices Market Outlook to 2016 15Asia-Pacific Orthopedic Devices Market Outlook to 2016 16Asia-Pacific Orthopedic Devices Market Outlook to 2016 17Asia-Pacific Orthopedic Devices Market Outlook to 2016 18Asia-Pacific Orthopedic Devices Market Outlook to 2016 19
Colibri style with 1.5 mm long angled tip and 0.12 mm teeth. Serrated handles with polished finish....
Curved shafts with 3.5 mm angled platform and dull finish. Wide serrated handle with dull finish....
Straight shafts with 4 mm jaws. Serrated handle with dull finish. Jaws straight....
Double-ended. 10 mm sickle shaped blade. 27 mm blunt, curved double-edged blade....
Medicine Products: