Navigation Links
GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.
Date:11/26/2007

nt boys and girls who are at least one year post-menarche, 10-17 years of age, with heFH if after an adequate trial of diet therapy the following findings are present:

1. LDL-C remains >189 mg/dL or

2. LDL-C remains >160 mg/dL and:

-- there is a positive family history of premature cardiovascular

disease or

-- two or more other CVD risk factors are present in the adolescent

patient

General Recommendations

Prior to initiating therapy with lovastatin, secondary causes for hypercholesterolemia (e.g., poorly controlled diabetes mellitus, hypothyroidism, nephrotic syndrome, dysproteinemias, obstructive liver disease, other drug therapy, alcoholism) should be excluded, and a lipid profile performed to measure total-C, HDL-C, and TG. For patients with TG less than 400 mg/dL (<4.5 mmol/L), LDL-C can be estimated using the following equation:

LDL-C = total-C - [0.2 x (TG) + HDL-C]

For TG levels >400 mg/dL (>4.5 mmol/L), this equation is less accurate and LDL-C concentrations should be determined by ultracentrifugation. In hypertriglyceridemic patients, LDL-C may be low or normal despite elevated total-C. In such cases, MEVACOR is not indicated.

The National Cholesterol Education Program (NCEP) Treatment Guidelines are summarized below:

NCEP Treatment Guidelines:

LDL-C Goals and Cutpoints for Therapeutic Lifestyle Changes

and Drug Therapy in Different Risk Categories

LDL Level at Which

LDL Goal to Initiate LDL Level at Which

Risk Category (mg/dL) Therapeutic to Consider Drug

Lifestyle Changes Therapy

(mg/dL) (mg/dL)

CHD+ or CHD risk <100 Greater Than or Equal Greater Than or Equal

equivalents
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

Related medicine news :

1. GlaxoSmithKline Responds to JAMA Articles
2. MedImmune Licenses Reverse Genetics Technology to GlaxoSmithKline for Use in Influenza Vaccine Development and Production
3. Congressional Black Caucus Foundation and GlaxoSmithKline Announce Supplier Business Initiative Study Results
4. AUDIO from Medialink and GlaxoSmithKline: A New Nasal Spray for Allergy Relief
5. Mylan Announces Settlement of Paroxetine Hydrochloride Extended-Release Tablets with GlaxoSmithKline
6. GlaxoSmithKline Aids California Fire Relief Efforts
7. Genmab and GlaxoSmithKline Initiate Ofatumumab Rheumatoid Arthritis Phase III Program
8. Ranbaxy Receives Tentative Approval to Manufacture and Market Galantamine Tablets on an Exclusive Basis
9. Southwest Ambulance Awarded Exclusive, 3-Year Contract Extension in Peoria, Arizona
10. Crdentias VP of Marketing, Christina Hogan, Provides Exclusive Interview on Marketing Strategy
11. Pearson VUE Signs Exclusive Contract with Educational Resources, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2015)... Las Vegas, NV (PRWEB) March 28, 2015 ... stiffness may not be necessary, according to research presented ... ( AOSSM ) Specialty Day. , “Our study compared ... with 25 who underwent an additional glenohumeral joint capsule ... surgery,” commented George Murrell MD, PhD, lead author from ...
(Date:3/28/2015)... Portland, OR (PRWEB) March 28, 2015 ... in the media regarding recent changes and proposals around ... TV , current and former collegiate student-athletes across a ... experiences and reflect on common challenges. The special panel ... the country in sports ranging from football, track and ...
(Date:3/28/2015)... 2015 Designers and Professionals of ... Scratches 5K from Pixel Film Studios. , “Scratches 5K ... media inside Final Cut Pro X” Said Christina Austin, ... and is an effective tool for any FCPX editor.” ... 5K's intuitive grunge overlays. Simply drag title layers into ...
(Date:3/28/2015)... 2015 LTW Cyber is an innovation ... for the purpose of addressing the needs of the ... its own opportunities to grow while seeking collaborative opportunities ... Cyber. , Ventures in LTW Cyber focus on secure ... offerings identifying vulnerabilities and analyzing open source. As ...
(Date:3/27/2015)... 27, 2015 Florida Hospital is excited to ... team’s exclusive health care provider for the 2015 and 2016 ... provides medical care and an athletic trainer for the team ... off its season against the Cleveland Gladiators at Amalie Arena; ... is extremely important to us as it gives us the ...
Breaking Medicine News(10 mins):Health News:No Need to Delay Rotator Cuff Surgery, Study Shows 2Health News:SCI TV Panel of Former College Athletes Discusses Student Athlete Experience 2Health News:SCI TV Panel of Former College Athletes Discusses Student Athlete Experience 3Health News:Pixel Film Studios Unveiled Scratches 5k for Final Cut Pro X Editors 2Health News:Canadian Cybersecurity Ventures Globalize as a Collective 2Health News:Canadian Cybersecurity Ventures Globalize as a Collective 3Health News:Florida Hospital Is Kicking off the 2015 Season as the Exclusive Health Care Provider for the Tampa Bay Storm 2Health News:Florida Hospital Is Kicking off the 2015 Season as the Exclusive Health Care Provider for the Tampa Bay Storm 3
... less likely than non-Hispanic whites to call 9-1-1 and be ... in medical treatment delays according to a new study ... ., For the study, researchers used data from the Brain ... hospital arrival time and use of ambulance or emergency medical ...
... with a coalition of 20 international sites in five ... who have had optical coherence tomography (OCT) of the ... researchers hope will give doctors a better means to ... and sudden cardiac death. When a vulnerable ...
... say , THURSDAY, March 25 (HealthDay News) -- New research ... cancer may actually improve their survival odds, a notion contrary ... finding is significant, given that the death rate from breast ... pregnancy until later in life, the study authors said. , ...
... compared to about three-quarters of whites, Hispanics, CDC says ... the health-boosting powers of breast-feeding aren,t reaching black American ... a new study from the U.S. Centers for Disease ... that while more than 80 percent of Hispanic mothers ...
... how tumors escape the body,s natural immune surveillance has recently ... Switzerland. The study shows how tumors can create a tolerant ... key features of lymph nodes. The discovery, published in ... 25, 2010, underscores the role of the lymphatic system in ...
... ... to Raise Awareness About Malaria Prevention Aboard an Eco-Friendly Bus , ... Atlanta, GA (Vocus) March 25, 2010 -- The United ... in Africa — announced today the launch of its Nothing But Nets Buzz Tour. The ...
Cached Medicine News:Health News:Mexican Americans less likely than whites to call 9-1-1 for stroke 2Health News:Mexican Americans less likely than whites to call 9-1-1 for stroke 3Health News:Mass. General Hospital to create registry for coronary optical coherence tomography 2Health News:Pregnancy May Protect Breast Cancer Survivors 2Health News:Pregnancy May Protect Breast Cancer Survivors 3Health News:Black Women Least Likely to Breast-Feed in U.S. 2Health News:Black Women Least Likely to Breast-Feed in U.S. 3Health News:Tumors hide out from the immune system by mimicking lymph nodes 2Health News:Grassroots Campaign Drives toward Ending Malaria Deaths by 2015 2Health News:Grassroots Campaign Drives toward Ending Malaria Deaths by 2015 3
(Date:3/27/2015)... BioCorRx, Inc. ( BICX ... is a healthcare solutions organization, which focuses solely on ... billion in the U.S. alone. The Company created a unique ... a specially compounded form for outpatient surgical implantation. The Company ... New Zealand ) to the specially formulated ...
(Date:3/27/2015)... CHAPEL HILL, N.C. , March 27, 2015 /PRNewswire/ ... function is essential to meeting challenges in clinical development, ... and face tighter regulations, the Medical Affairs function is ... charted by mature markets. According to ... market study participants have a group dedicated to Medical ...
(Date:3/27/2015)... 27, 2015  The quality function within the medical ... meet quality standards at every stage of the product ... leaders also have the challenge of balancing quality and ... who don,t effectively balance these priorities risk funding and ... failure and regulatory scrutiny. For the third ...
Breaking Medicine Technology:Small Cap IR Correction -- BioCorRx Inc. Positions Itself Through Strategic Partnerships To Gain Market Share Of The $22 Billion Substance Abuse Treatment Market In The U.S. 2Medical Affairs Capabilities Expanding in Emerging Marketplaces 2New Medical Device Quality Study Finds Regulatory Environment is Boosting Quality Spending, Especially for Large Companies 2
... If you prefer a standard ... the Volk Iridectomy Lens. Its ... view you're used to but ... Volk's exclusive Double Aspheric design ...
... The re-designed Super Macula® 2.2 offers extremely ... the fovea, while achieving an exceptionally wide ... an excellent choice for critical evaluation of ... stereopsis for detailed views of the macula ...
... is designed for focal laser therapy and ... design presents a realistic contour of the ... of the entire posterior pole extending to ... lens allows dynamic movement on the globe, ...
... The Digital 1.0x Imaging Lens is optimized ... reduce glare and reflections during general diagnosis and ... view of the posterior pole and a sharper ... Digital 1.0 X Imaging Lens is also ideal ...
Medicine Products: