Navigation Links
Glaucoma Begins in Mid-Brain, Not in Eye, Research Shows
Date:3/3/2010

Animal study shows degeneration occurring in reverse order than commonly believed

WEDNESDAY, March 3 (HealthDay News) -- Early signs of glaucoma can be detected in the brain, according to a new study that may trigger a major change in how the disease is treated.

It has long been believed that glaucoma -- the leading cause of blindness in the United States -- results from pressure within the eye that damages the retina and optic nerve, so treatments have focused on reducing pressure within the eye. However, this new study suggests that glaucoma is a central nervous system disease that requires different treatment approaches.

"This is a paradigm shift in how we think about the disease," study author David Calkins, director of research at the Vanderbilt Eye Institute, said in a news release from the Vanderbilt University Medical Center. "This will have global implications. This information opens up an entirely new domain of nerve-derived therapeutics."

In research with lab animals, Calkins and his team found that a very early mechanism of glaucoma-related vision loss involves deterioration of communication between the optic nerve and the mid-brain, which handles information about sensory input such as sound, heat, cold, pain and pressure.

"If you followed the disease long enough, eventually the optic nerve, then the retina, show signs of degeneration," Calkins explained. "So the degeneration works in reverse order. It starts in the brain and works its way back to the retina so that in the very latest stages of the disease, the earliest structures, the one nearest the eye, are the last to go."

The study findings were released online March 1 in advance of publication in an upcoming print issue of the journal Proceedings of the National Academy of Sciences.

More information

The U.S. National Eye Institute has more about glaucoma.



-- Robert Preidt



SOURCE: Vanderbilt University Medical Center, news release, March 1, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
2. Glaucoma surgery in the blink of an eye
3. Glaucoma surgery in the blink of an eye
4. Chair of U.S. Preventive Services Task Force Pledges to Recommend Re-evaluation of Recent Glaucoma Findings
5. Looking at Glaucoma as a Systemic Disease
6. Cost of glaucoma medications may impact treatment
7. January is National Glaucoma Awareness Month
8. Upcoming meeting will explore new technologies for glaucoma clinical drug trials
9. Dr. Welsh Self-Test Diagnoses Glaucoma, the Leading Cause of Preventable- Blindness
10. Mayor Bloomberg Declares March 6, 2008 World Glaucoma Day in New York City
11. Glaucoma May Boost Cardiovascular Death Risk in Blacks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... 10, 2016 , ... Everseat has joined the award-winning Allscripts ... physicians. The integration will enable Allscripts users to post open appointments to the ... app. , The partnership gives Everseat substantial added power to help Allscripts meet ...
(Date:2/10/2016)... ... February 10, 2016 , ... Workrite Ergonomics, who is celebrating their 25th ... humble beginnings to being an internationally recognized leader in their industry. , "We are ... Charlie Lawrence, President of Workrite. “Workrite recognized the importance of good ergonomics before ...
(Date:2/10/2016)... ... February 09, 2016 , ... Western University ... free oral screenings to 150 children in kindergarten through third grade at Hurley ... Dental Medicine joined Chinese American Dental Society of Southern California volunteers for Give ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... It’s that ... Traci Davis, the new president of the Interscholastic Athletic Association of Maryland (IAAM), Hall ... well how quickly fitness goals are cast aside. , That’s why one of her ...
(Date:2/9/2016)... ... , ... February is Heart Awareness Month, and to celebrate Health Quest Chiropractic ... the American Heart Association, New Mexico chapter. , A Heart Rate Variability (HRV) scan ... INSiGHT Pulse Wave Profiler utilizes a non-invasive technology to determine a heart’s ability to ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... Mass. , Feb. 9, 2016   AllCare ... The Joint Commission,s Gold Seal of Approval ® ... compliance with its performance standards. The Gold Seal of ... reflects an organization,s commitment to providing safe and effective ... AllCare Plus Pharmacy underwent a rigorous on-site survey ...
(Date:2/9/2016)... The global prefilled syringes market accounted for $3,905.1 million ... with a CAGR of 12.9% during 2015-2020. Among the ... global prefilled syringes market, with 90.1% share in 2014. ... global market of prefilled syringes is up surging with ... demand for vaccines, increasing prevalence of chronic and lifestyle ...
(Date:2/9/2016)... Calif. , Feb. 9, 2016  Increasingly, health ... monitoring their vital signs with wireless technology. With the ... can automate patient oversight and remotely detect problems before ... vital signs across in-hospital environments. the ... the United States . --> ...
Breaking Medicine Technology: