Navigation Links
Gladstone scientists develop technique to decipher the dormant AIDS virus concealed in cells
Date:9/11/2012

SAN FRANCISCO, CASeptember 11, 2012Scientists at the Gladstone Institutes have gotten us one step closer to understanding and overcoming one of the least-understood mechanisms of HIV infectionby devising a method to precisely track the life cycle of individual cells infected with HIV, the virus that causes AIDS.

In a paper being published online today in Lab on a Chip, the laboratory of Gladstone Investigator Leor Weinberger, PhD, announced the development of a device that can pinpoint and track HIV inside CD4 T cellsthe type of white blood cell that the AIDS virus targets. This development is particularly important for understanding "HIV latency," a state in which the virus goes dormant after the patient begins standard antiretroviral treatment. Current antiretroviral drugs do not kill HIVthey only keep it at baymeaning that those with HIV must continue a lifetime of drug treatment so as not to develop AIDS. If they discontinue the drugs, the latent virus "wakes up" within just a few weeks and begins an onslaught against the body's immune system.

The breakthrough comes as the AIDS-researcher community is beginning to speak publicly about the possibility of curing HIV/AIDS. Understandingand consequently interruptingHIV latency is a key element in the effort to discover a cure for this devastating disease.

"HIV latency is perhaps the single greatest obstacle to eradicating HIV/AIDS in the 34 million people who live with the disease worldwide," said Dr. Weinberger, who is also an associate professor of biochemistry and biophysics at the University of California, San Francisco (UCSF), with which Gladstone is affiliated. "Existing techniques that try to uncover the cellular and viral mechanisms behind HIV latency are inefficient at studying very rare cellsand cells housing the latent HIV virus are one-in-a-million. Our technique presents a clear path towards understanding how HIV latency is regulated within a single cell, by tr
'/>"/>

Contact: Anne Holden
anne.holden@gladstone.ucsf.edu
415-734-2534
Gladstone Institutes
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Gladstones Lennart Mucke receives Lifetime Achievement Award from the Alzheimers Association
2. Reconstructed 1918 influenza virus has yielded key insights, scientists say
3. Scientists put a pox on dog cancer
4. MBL and Stanford scientists receive 2012 Lasker Award for Basic Medical Research
5. Scientists Inch Closer to Genetic Blueprint of Diseases
6. Scientists Find Links Among Parkinsons, Cancer and Family History
7. Danish scientists solve old blood mystery
8. First validated method for analyzing flavanols and procyanidins in cocoa products could help scientists and the industry in standardized reporting
9. Scientists ID Happy Gene in Women
10. NIH scientists map first steps in flu antibody development
11. Scientists to design drug for chronic pain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gladstone scientists develop technique to decipher the dormant AIDS virus concealed in cells
(Date:8/21/2014)... 2014 Florida Hospital Zephyrhills is ... of the only in the Tampa Bay area ... the Olympus Endoalpha Universal Platform for surgical endoscopy. ... endoscopic specialties, and provides the hospital a standardized ... efficiencies and patient care. Surgical endoscopy systems, through ...
(Date:8/21/2014)... NY (PRWEB) August 21, 2014 Local ... often have larger discounts for specific protection plans, according ... now helping consumers to quote life insurance from local ... , The local agents that appear inside of the ... a fast method of price reviews this year. Adults ...
(Date:8/21/2014)... August 11: – Robin William’s suicide was ... hanging, likely due to long-term depression. , ... Vocal Profiling investigator, appeared on the Joyce Riley Power ... hoping to help people understand why he chose not ... were proposed in terms of BioAcoustic Biology: Using vocal ...
(Date:8/21/2014)... The “Proteomics Market by Technology ... Surface Plasmon Resonance, X-ray Crystallography) - Instruments, Reagents ... and studies the major market drivers, restraints, and ... Rest of the World (RoW) , Browse 138 ... pages and in-depth TOC on “Proteomics Market by ...
(Date:8/21/2014)... 22, 2014 DoudouneCanadienneGoosePasCher.fr, one of the ... has recently unveiled its new selection of Trillium Parkas ... announced that all these fashionable and comfortable items are ... special offer will last until September 01. , ... the new Canada Goose Trillium Parkas for ...
Breaking Medicine News(10 mins):Health News:Florida Hospital Zephyrhills is Elevating Healthcare by Offering the First Olympus Fully-Integrated HD Operating Room in Pasco County 2Health News:Florida Hospital Zephyrhills is Elevating Healthcare by Offering the First Olympus Fully-Integrated HD Operating Room in Pasco County 3Health News:Life Insurance from Local Agents Now Priced Nationally Through Complimentary Tool Online 2Health News:Robin Williams: What he could not bear to face 2Health News:Robin Williams: What he could not bear to face 3Health News:Proteomics Market worth $20,696.4 Million by 2018 - New Research Report by MarketsandMarkets 2Health News:Proteomics Market worth $20,696.4 Million by 2018 - New Research Report by MarketsandMarkets 3Health News:Proteomics Market worth $20,696.4 Million by 2018 - New Research Report by MarketsandMarkets 4Health News:Proteomics Market worth $20,696.4 Million by 2018 - New Research Report by MarketsandMarkets 5Health News:Fashionable And Comfortable Canada Goose Trillium Parkas For Sale At DoudouneCanadienneGoosePasCher.fr 2
... ... 2009. , ... October 16, 2009 -- Tony Rico has recently been promoted to Senior Vice President of ... promotion was effective September 1, 2009. , , , , ,"This position has ...
... A bioethicist who specializes in moral dilemmas families face ... honored with the first-ever March of Dimes Distinguished Lectureship ... a nationally-recognized pediatrician and ethicist, will deliver his lecture ... the American Society of Bioethics and Humanities, 11th annual ...
... Feature Gena Rowlands , EAST BRUNSWICK, N.J., Oct. 15 ... home to New Jersey to host a celebrity cocktail reception ... will raise money for National MS Society,s New Jersey Metro ... Jersey, where it is estimated that almost 10,000 people have ...
... 15 ResMed Inc. (NYSE: RMD ), announced today that ... the first quarter of fiscal year 2010, ended September 30, 2009. ... p.m. Pacific Time and the Company will host a conference call ... , The conference call is scheduled to begin at 1:30 p.m. ...
... AUSTIN, Texas, Oct. 15 deverus, inc., a ... for background screening companies, announced today that Corporate ... deverus, Verocity 2009 software platform to provide an ... An affiliate of Corporate Research and Investigations (Pvt.) ...
... WASHINGTON, Oct. 15 A National Awareness Campaign to ... Arabia to coincide with international Breast Cancer Awareness month. The campaign ... of the Zahra Breast Cancer Association and wife of the ... , and Princess Rima bint Abdullah bin Abdulaziz. It officially ...
Cached Medicine News:Health News:Jackson & Coker Promotes Tony Rico to Senior VP of Operations 2Health News:March of Dimes Establishes Two New Perinatal Bioethics Awards 2Health News:March of Dimes Establishes Two New Perinatal Bioethics Awards 3Health News:East Brunswick Native Returns Home to Help New Jersey Residents Living with MS 2Health News:ResMed Announces Conference Call and Webcast to Discuss First Quarter 2010 Results 2Health News:deverus(TM) Expands Operations Overseas 2
(Date:8/21/2014)... -- Vermillion, Inc. (NASDAQ: VRML ), a multivariate ... has appointed Holly B. Bauzon as Vice ... Bauzon has a proven track record in both increasing ... companies. She has more than 20 years of healthcare ... the position of Director, Lab Services Sales and Managed ...
(Date:8/21/2014)...  eRelevance Corporation ( www.erelevancecorp.com ), a progressive ... has completed integration with Nextech, a popular Electronic ... Dermatology practices. "Integration allows our service ... using Nextech," stated Bob Fabbio , co-founder ... the EMR we are able to automatically target ...
(Date:8/21/2014)... NEW YORK , Aug. 21, 2014  Publicis ... Shannon Hartley , Managing Partner and Healthcare Industry ... of PharmaVoice 100, which recognizes the most inspiring people ... group are leaders in research and development, marketing, technology, ... the agency in 2006 as a partner in its ...
Breaking Medicine Technology:Vermillion Appoints Holly B. Bauzon as VP of Sales and Managed Markets 2eRelevance Corporation Integrates with Nextech Electronic Medical Records 2Shannon Hartley Shines in PharmaVOICE 100 2
... The AXA Research Fund closed out its first year ... than Euro 13 million to various European research institutions.The purpose ... of major risks in the world by supporting cutting edge ... Euro 100 million over five years, making it a major ...
... Research features from Mayo ClinicROCHESTER, Minn., March 23 ... of Discovery,s Edge, Mayo Clinic,s research magazine. You ... often as you wish. Reprinting is allowed with ... as your editorial policies permit: Visit http://discoverysedge.mayo.edu ...
Cached Medicine Technology:First Year Results of the AXA Research Fund: Over Euro 13 Million Allocated for Research in 2008 2First Year Results of the AXA Research Fund: Over Euro 13 Million Allocated for Research in 2008 3Discovery's Edge Spring Issue - http://discoverysedge.mayo.edu 2
... Endoscopic CycloPhotocoagulation (ECP) is a surgical ... endoscopy and visualized laser application. The ciliary ... by the surgeon, from the anterior or ... time. The target tissues are easily and ...
... surgical approach to glaucoma management that employs ... ciliary body (which produces aqueous humour) is ... or posterior segment, through the endoscope in ... and accurately identified utilizing endoscopy. This allows ...
... German Craftsmanship have produced the ... world. Ocutek® now makes them ... of the coveted Meisterbrief certificate, ... are qualified to become Ocutek ...
... Centuries of German Craftsmanship ... instrumentation in the world. Ocutek® ... you! Only holders of the ... and eight-year apprenticeship, are qualified ...
Medicine Products: