Navigation Links
Giving transplanted cells a nanotech checkup
Date:2/5/2013

Researchers at Johns Hopkins have devised a way to detect whether cells previously transplanted into a living animal are alive or dead, an innovation they say is likely to speed the development of cell replacement therapies for conditions such as liver failure and type 1 diabetes. As reported in the March issue of Nature Materials, the study used nanoscale pH sensors and magnetic resonance imaging (MRI) machines to tell if liver cells injected into mice survived over time.

"This technology has the potential to turn the human body into less of a black box and tell us if transplanted cells are still alive," says Mike McMahon, Ph.D., an associate professor of radiology at the Johns Hopkins University School of Medicine who oversaw the study. "That information will be invaluable in fine-tuning therapies."

Regenerative medicine advances depend on reliable means of replacing damaged or missing cells, such as injecting pancreatic cells in people with diabetes whose own cells don't make enough insulin. To protect the transplanted cells from the immune system, while allowing the free flow of nutrients and insulin between the cells and the body, they can be encased in squishy hydrogel membranes before transplantation. But, explains McMahon, "once you put the cells in, you really have no idea how long they survive." Such transplanted cells eventually stop working in most patients, who must resume taking insulin. At that point, physicians can only assume that cells have died, but they don't know when or why, says McMahon.

With that problem in mind, McMahon's group, which specializes in methods of detecting chemical changes, collaborated with the research group headed by Jeff Bulte, Ph.D., the director of cellular imaging at Hopkins' Institute for Cell Engineering. Bulte's group devises ways of tracking implanted cells through the body using MRI. Led by research fellow Kannie Chan, Ph.D., the team devised an extremely tiny, or nanoscale
'/>"/>

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Immigrant women giving birth in Spain suffer great stress, a study warns
2. Giving makes young children happy, UBC study suggests
3. The Alzheimer’s Caregiver™ Offers a New Educational Concept of Care That Bridges the Gap between Research and Caregiving
4. 3M™ Gripping Material Technology – Giving Golfers a Competitive Edge
5. 1 in 3 post-partum women suffers PTSD symptoms after giving birth
6. Giving lithium to those who need it
7. Kessler Foundation scientists report negative impact of long-term caregiving on cognition
8. Kick Off the Holiday Season With a Healthier Thanksgiving
9. Spread the Purple Launches New Website Just in Time for Winter Holiday Giving Season
10. Omega3 Innovations Helps Local Food Bank Provide Thanksgiving Dinners for those in Need
11. Zion Health Announces Holiday Earth Gifts for the Season of Giving Now Available at Whole Foods Market in Lafayette, CA
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Giving transplanted cells a nanotech checkup
(Date:7/23/2014)... Home Care Assistance Calgary , North America’s ... to announce the next installment in its renowned Healthy ... of health and wellness-related fields. The upcoming webinar will ... Kriseman, and will cover the most common causes of ... more self-aware. In particular, Nancy will discuss mindfulness and ...
(Date:7/23/2014)... (HealthDay News) -- Regularly checking the pulse of a ... "Screening pulse is the method of choice for ... who have never had a stroke. Our study shows ... way to identify people who might need more thorough ... Dr. Bernd Kallmunzer, of Erlangen University in Germany. ...
(Date:7/23/2014)... Institute of Biomedical Imaging and Bioengineering will host its ... 30, 2014 on the NIH campus. There will be ... wide breadth of NIBIB-funded research. , WHO: ... Microbial Rhodopsins as Optical Voltage Sensor, Quyen Nguyen, ... for Nerve Imaging during Surgery, ...
(Date:7/23/2014)... July 23, 2014 Global Cardio Care, ... Enhanced External Counterpulsation (EECP), is celebrating the 100th ... therapy at the health center. , Weber has ... Since receiving ongoing EECP therapy since 1999, he no ... Soulati, CEO of Global Cardio Care, introduced the ...
(Date:7/23/2014)... Fragile X syndrome ( FXS ) is a ... other behaviors on the autistic spectrum, as well as ... of mental impairment and the most common cause of ... California, Riverside have published a study that ... FXS. Appearing online today (July 23) in the ...
Breaking Medicine News(10 mins):Health News:Home Care Assistance Calgary to Host Public Webinar on the Topic of Caregiver Mindfulness 2Health News:Home Care Assistance Calgary to Host Public Webinar on the Topic of Caregiver Mindfulness 3Health News:Routine Pulse Check May Prevent Second Stroke, Study Says 2Health News:Global Cardio Care Celebrates EECP Patient’s 100th Birthday 2Health News:Study links enzyme to autistic behaviors 2Health News:Study links enzyme to autistic behaviors 3
... The following is a,statement from the Trust for America,s ... major health crisis because the United States does not,have ... Americans are uninsured;, Tens of millions of Americans ... $2 trillion a year on medical care, more than,any ...
... have done it again!, SAN DIEGO, Dec. 14 ... Young -- The Owner,s Manual for,Extending Your Warranty, lived up ... Diet, both New York Times #1 best-sellers. Within days,of its ... and,Barnes & Noble.com. Within just a few weeks, it became ...
... Dec. 14 Following is a statement,by Linda ... Products,Association (CHPA), regarding the recommendations of the U.S. ... phenylephrine:, "Phenylephrine 10 mg is safe when ... effective for nasal decongestion in multiple clinical trials.,Today, ...
... more than 8 years of follow-up, older women taking ... Dec. 14 (HealthDay News) -- The aromatase inhibitor drug ... it comes to preventing recurrences of hormone-receptor-positive breast cancers ... was stopped, women taking Arimidex still saw a benefit, ...
... Veridex, LLC, a,Johnson & Johnson company, is pleased ... Lymph Node (BLN) Assay one of the top ten,medical ... of the magazine, available today, TIME,states: "Surgeons now have ... With GeneSearch(TM) BLN Assay, TIME goes on to say, ...
... Indiana Plan Combines Personal Responsibility and Public,Dollars, ... announced the approval of a Medicaid waiver that ... innovative health care proposal giving,approximately 120,000 low-income, uninsured ... waiver, the state will be able to begin,accepting ...
Cached Medicine News:Health News:TFAH Board of Directors Issues Statement on U.S. Health Care Crisis 2Health News:YOU: Staying Young Fourth New York Times Best-Seller for RealAge Test Creator Dr. Michael Roizen! 2Health News:Statement from the Consumer Healthcare Products Association on Today's FDA Advisory Committee Meeting on the Efficacy of Phenylephrine in the 10 Mg Oral Dose 2Health News:Arimidex Beats Tamoxifen in Keeping Breast Cancer at Bay 2Health News:Arimidex Beats Tamoxifen in Keeping Breast Cancer at Bay 3Health News:TIME Magazine Names GeneSearch(TM) One of the Top 10 Medical Breakthroughs in 2007 2Health News:TIME Magazine Names GeneSearch(TM) One of the Top 10 Medical Breakthroughs in 2007 3Health News:TIME Magazine Names GeneSearch(TM) One of the Top 10 Medical Breakthroughs in 2007 4Health News:HHS Approves Medicaid Waiver to Create New Indiana Health Plan for Uninsured Hoosiers 2
(Date:7/23/2014)... 23, 2014 The Board of Directors of ... provider of clinical trial imaging solutions, announced today that ... president and chief executive officer, effective immediately.  Mr. Converse ... and has held the positions of interim president and ... Dr. Charles E. Phelps , Ph.D., chairman of ...
(Date:7/23/2014)... July 23, 2014 Research and Markets ... (ECG) Market by Product, End-user & by Lead Type ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... into three major segments, namely, holter monitor, resting, and ... valued at $3,683 million in 2013 and is poised ...
(Date:7/23/2014)... July 23, 2014 On Tuesday, July ... filed suit in the 116 th Judicial ... , against RegenLab USA, LLC ("Defendant") ... Business Relationships through false and misleading actions, ... Business Disparagement through libel, disparagement, defamation, misrepresentation, ...
Breaking Medicine Technology:Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 2Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 3Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 4Global Diagnostic Electrocardiograph (Resting, Stress, Holter Monitor) (ECG) Market - Forecast to 2020 2Global Diagnostic Electrocardiograph (Resting, Stress, Holter Monitor) (ECG) Market - Forecast to 2020 3
... such as laparoscopic inguinal hernia repair ... a surgical biomaterial that enables rapid ... provides the answer to the most ... Made from strong, soft, inert and ...
... is the Bard Kugel Patch, which is constructed ... two layers create a positioning pocket, which is ... position. On the other side is a barrier ... "memory recoil ring," which causes the patch to ...
... patch repair is a minimally invasive, tension-free ... small 4-6 cm incision and requires minimal ... through an open, anterior approach that can ... Modified Kugel patch is a self-expanding polypropylene ...
... Lyra-i system combines the longest available wavelength ... maximize patient safety and efficacy. The unique ... the therapeutic range to all targeted structures. ... ensuring patient safety. All Lyra-I patients are ...
Medicine Products: