Navigation Links
Ginkgo Won't Prevent Heart Attack, Stroke in Elderly
Date:11/24/2009

But the herbal supplement may help ward off peripheral artery disease, researchers say

TUESDAY, Nov. 24 (HealthDay News) -- Among people aged 75 and older, the herbal supplement Ginkgo biloba does not prevent heart attacks, stroke or death, a new study finds.

There is some evidence that the popular herbal remedy might help prevent the leg-circulation problem known as peripheral artery disease, however.

Ginkgo contains nutrients called flavonoids, which are also found in fruits, vegetables, dark chocolate and red wine, and are believed to offer some protection against cardiovascular events, the researchers say. The supplement, which is popular in the United States and Europe, has been touted to improve memory, and to prevent dementia, heart disease and stroke.

However, "ginkgo had no benefit in preventing heart attack or stroke," said study lead researcher Dr. Lewis H. Kuller, distinguished university professor of public health and professor of epidemiology at the University of Pittsburgh.

"But, surprising to us, was that the results were consistent with the observations in Europe that ginkgo appeared to have some benefit in preventing peripheral vascular disease," he said.

This could be due to flavonoids acting as both antioxidants and also causing blood vessels to expand, Kuller said.

The report was released online Nov. 24 in advance of publication in an upcoming print issue of the journal Circulation. Last year the same University of Pittsburgh team reported that ginkgo biloba had no effect on preventing dementia.

For their latest study, Kuller's group randomly assigned 3,069 patients to 120 milligrams of highly purified ginkgo biloba or placebo, twice a day as part of the Ginkgo Evaluation of Memory Study.

Over the six years of the trial, 385 participants died, 164 had heart attacks, 151 had strokes, 73 had mini-strokes ("transient ischemic attacks") and 207 had chest pain, the researchers found.

There was no significant difference between those taking ginkgo or placebo for any of these outcomes, Kuller said.

However, among the 35 people who were treated for peripheral artery disease, 23 received placebo and 12 were taking ginkgo -- a statistically significance difference, the researchers noted.

About 8 million Americans have peripheral artery disease, which typically affects the arteries in the pelvis and legs. Symptoms include cramping and pain or tiredness in the hip muscles and legs when walking or climbing stairs, although not everyone who has PAD is symptomatic. The pain usually subsides during rest.

"This study demonstrated that there were absolutely no benefits of ginkgo biloba in reducing cardiovascular events such as heart attack or stroke or in reducing death due to cardiovascular disease," said Dr. Gregg A. Fonarow, a professor of cardiovascular medicine at the University of California, Los Angeles.

"Individuals interested in maintaining cardiovascular health should stick to interventions that have been proven to be beneficial, including not smoking, engaging in regular exercise, and maintaining healthy weight, blood pressure and cholesterol levels rather than taking herbal supplements," Fonarow said.

Mark Blumenthal, founder and executive director of the American Botanical Council, which represents the herbals industry, pointed to the study's more positive outcome.

"I believe it is important to emphasize that the results of this current exploratory trial do not in any manner reduce or negate the existing positive results of ginkgo biloba as an effective treatment in peripheral artery disease patients, which has been evaluated, confirmed, and approved by government regulatory drug authorities in leading Western European countries like Germany and France," he said.

In addition, Blumenthal said, the trial showed that ginkgo biloba was safe and well-tolerated.

More information

Find out more about ginkgo biloba at the U.S. National Library of Medicine.



SOURCES: Lewis H. Kuller, M.D., Dr.P.H., distinguished university professor, public health and professor of epidemiology, University of Pittsburgh; Mark Blumenthal, founder and executive director, American Botanical Council; Gregg A. Fonarow, M.D., professor, cardiovascular medicine, University of California, Los Angeles; Nov. 24, 2009, Circulation, online


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Tianyin Pharmaceutical Co. Inc.s Ginkgo Mihuan Oral Solution Completes 2009 Tenders
2. Ginkgo Biloba for Prevention of Dementia
3. Ginkgo No Shield Against Alzheimers
4. Ginkgo Biloba Might Not Preserve Memory in Octogenarians
5. Strict Blood Sugar Lowering Wont Ease Diabetes Heart Risk
6. Protein from pregnancy hormone may prevent breast cancer
7. Infection Prevention Online Community Site Launches - Focused on Product Selection
8. National Medical Association Response to U.S. Preventive Services Task Force Recommendations
9. Preventing H1N1 spread to health care workers: Dilemma, debate and confusion
10. Pennsylvania Department of Health Releases H1N1 Flu Prevention Music Video
11. U.S. Preventive Medicine Introduces The Prevention Score(TM)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... NJ (PRWEB) , ... April 28, 2017 , ... Horizon ... has affirmed the company’s credit rating of “A” and its outlook as “stable.” At ... if capital reserves, which have fallen in recent years, dip below “capital adequacy” thresholds ...
(Date:4/28/2017)... York, NY (PRWEB) , ... April 28, 2017 ... ... Medical Laboratory to expanded distribution of the GlycoMark test throughout the Northeast U.S. ... recent hyperglycemia in patients with diabetes. The GlycoMark test provides a clinically proven ...
(Date:4/28/2017)... ... 2017 , ... Ushio America proudly introduces the new ... solution for F32T8 fluorescent lamps on most instant-start and programmed-start electronic ballasts so ... lamps utilize the existing electronic ballast, saving labor and maintenance costs. It’s easy ...
(Date:4/28/2017)... New york (PRWEB) , ... April 28, 2017 ... ... pleased to announce that Aditya Patel M.D. has joined the revolutionary endoscopic practice ... training and board certification in Interventional Pain Medicine. The patented, revolutionary eDiscSculpt Technique ...
(Date:4/28/2017)... ... 2017 , ... The Texas Cord Blood Bank (TCBB), a program of nonprofit ... at Women’s Hospital at Renaissance in Edinburg for their outstanding efforts in collecting umbilical ... to donate. , “Women’s Hospital at Renaissance has been a collection partner for ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017  Cogentix Medical, ... focused on providing the Urology, Uro/Gyn and Gynecology ... that Ash Keswani has joined the Company as ... this newly created position, Mr. Keswani will report ... CEO. "Our organization is delighted that ...
(Date:4/20/2017)... 20, 2017  RXi Pharmaceuticals Corporation (NASDAQ: RXII), ... address significant unmet medical needs, today announced that ... consumer product development program, based on its proprietary ... Investigative Dermatology (SID) 76 th Annual Meeting.  ... the sciences relevant to skin health and disease ...
(Date:4/20/2017)... , April 20, 2017  AbbVie (NYSE: ABBV), ... percent (n=145/146) of chronic hepatitis C virus (HCV) ... or 6 and compensated cirrhosis (Child-Pugh A) achieved ... 12 ) with its investigational, pan-genotypic regimen of ... were seen following 12 weeks of G/P treatment ...
Breaking Medicine Technology: