Navigation Links
Ginkgo Biloba for Prevention of Dementia

KARLSRUHE, Germany, Nov. 18 /PRNewswire/ -- Schwabe, the manufacturer of the Ginkgo extract EGb 761(R), believes that the GEM study results do not allow a final conclusion on the potential of the extract in dementia prevention.

GEM is one of five studies that have been or are investigating the effect of standardized Ginkgo extract on the prevention of dementia. The GEM study investigated the probability of developing dementia in 3069 subjects (average age on entry 79 years) receiving either 240 mg EGb 761(R) or placebo daily. Over the 6-year treatment period, compliance fell to only 60%.

Previous results from two epidemiological studies in France showed a positive influence of EGb 761(R) on the onset of Alzheimer's and length of survival without dementia, thus raising expectations that EGb 761(R) might prove useful in this context. Earlier this year an NIH sponsored study showed a positive effect of standardized Ginkgo biloba extract on the risk of developing dementia only in those participants who took their medicine regularly. Another large scale study with EGb 761(R), the GUIDAGE study with 2854 patients aged 70 and above, is currently ongoing in France. Schwabe believes that the results of that study should be awaited before a fuller assessment of the potential of EGb 761(R) in dementia prevention can be made.

It is also important to note that the outcome of the GEM study in no way affects or detracts from the efficacy of EGb 761(R) in the treatment of manifest Alzheimer's as proven in a number of clinical studies, e.g. most recently presented at the International Conference on Alzheimer's Disease (ICAD) in Chicago in July 2008 [1]. There, EGb 761(R) was shown to improve cognition as well as neuropsychiatric symptoms and activities of daily living in dementia patients. Furthermore, it not only benefited the patients themselves but in addition provided significant relief to the care-giving relatives.

To date, there are no medications available for prevention of dementia and all attempts to demonstrate prophylactic action have so far failed. This applies to approved dementia drugs as well as to other active substances such as acetylsalicylic acid, vitamin E, hormones, or NSAIDs.

This makes it all the more important to support the cognitive performance at an appropriately early stage. EGb 761(R) has recently been shown to improve concentration as well as memory and learning ability in individuals over 45 with mild cognitive deficits [2].

About Schwabe

Dr. Willmar Schwabe Pharmaceuticals, headquartered in Karlsruhe, Germany, was founded in 1866. For more than 140 years, Schwabe Pharmaceuticals has been dedicated to providing patients and health care professionals with clinically proven herbal medicines and natural health care solutions. Today, the group is the global leader in the manufacturing of herbal medicines.


     Prof. Dr. med. Michael Habs
     Dr. Willmar Schwabe GmbH & Co. KG
     Willmar-Schwabe-Str. 4
     76227 Karlsruhe
     Telefon: (0721) 40 05-498
     Telefax: (0721) 40 05-500

    [1] Ihl R, Tribanek M, Napryeyenko O. A 240-mg Once-Daily Formulation of
        Ginkgo biloba Extract EGb 761(R) is Effective in Both Alzheimer's
        Disease and Vascular Dementia: Results from a Randomized Controlled
        Trial.  Alzheimer's & Dementia 2008;4(suppl 2):T165-T166.
    [2] Hoerr R, Grass-Kapanke B, Tribanek M, Kaschel R. Effects of Ginkgo
        biloba extract EGb 761(R) on cognition and quality of life in
        subjects with very mild cognitive impairment. International Journal
        of Psychology 2008;43:404.

SOURCE Schwabe Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. Ginkgo No Shield Against Alzheimers
2. Ginkgo Biloba Might Not Preserve Memory in Octogenarians
3. AACR to host 7th Annual International Conference on Frontiers in Cancer Prevention Research
4. Leading Physicians To Host Medical Device Related Infection Prevention CME Webcast
5. New Health Retreat Gives a Fresh Attitude Towards Disease Prevention
6. Measles Initiative Supports Disease Prevention for Children in Chinas Earthquake Zone
7. Vitamins E and C supplements not effective for prevention of cardiovascular disease in men
8. U.S. Preventive Medicine(R) Awards Inaugural Global Prevention Prize to Dr. Valentin Fuster of Mount Sinai Heart
9. Obama's Call for "Change We Can Believe In" Makes Prevention a Priority in Health Reform
10. Nov. 10 Webinar on Dementia Prevention in Senior Communities to Discuss Brain Fitness Programming with UCLAs Dr. Gary Small
11. North Dakota Votes to Keep Promise to Kids by Fully Funding Tobacco Prevention
Post Your Comments:
(Date:11/24/2015)... ... November 24, 2015 , ... The American Association of ... local poison centers through donations on Tuesday, Dec. 1, 2015. Since 2012, the ... that inspires people to collaborate in improving their local communities and help give ...
(Date:11/24/2015)... ... November 24, 2015 , ... Aided by seed funding from the Ron ... designed to yield insights into how to detect and treat pancreatic cancer (PC). ... from small, non-coding RNA molecules (ncRNA), genetic material that is present in the blood ...
(Date:11/24/2015)... ... , ... Dr. Rodney E. Willey , has answered a new calling – to relieve ... provides treatment for snoring and sleep apnea through oral appliance therapy. He ... Disorders in the US, one of four in the Illinois area. , Dr. Willey’s ...
(Date:11/24/2015)... ... November 24, 2015 , ... Autism Speaks, the world’s leading ... driven by social media and the generosity of people around the world. On December ... media networks to give – and share the personal stories behind those gifts. ...
(Date:11/24/2015)... ... November 24, 2015 , ... Robert Yeager ... Report . Throughout the past year there have been multiple breakthroughs and challenges as ... this transition, PharmMD has enabled their customers and partners to stay ahead of the ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... LONDON , November 24, 2015 ... PCSK9 Inhibitors, CETP Inhibitors, MTTP Inhibitors, ApoB Inhibitors and ... areas are going to grow at the fastest rates? ... to 2025, assessing data, trends, opportunities and prospects there. ... graphs. Discover the most lucrative areas in the industry ...
(Date:11/24/2015)...  Enova Illumination is pleased to announce a new ... to combine their world class camera and ... of medical visualization: Enova is the first manufacturer of ... and Novocam is the manufacturer of HD ... most powerful battery-operated LED headlight with high-quality point-of-view video ...
(Date:11/24/2015)... Calif. , Nov. 24, 2015 Abaxis, ... manufacturing point-of-care instruments and consumables for the medical, research, ... Taylor , Chief Financial Officer, will present at the ... Tuesday, December 1, 2015 at 11:30 a.m. ET. The ... Palace in New York City . ...
Breaking Medicine Technology: