Navigation Links
Ginkgo Biloba Might Not Preserve Memory in Octogenarians
Date:2/28/2008

Study saw no clear benefit, but did see small number of strokes, mini-strokes

THURSDAY, Feb. 28 (HealthDay News) -- Ginkgo biloba, the popular herbal supplement widely promoted as a memory enhancer, offered no clear-cut protection against memory loss in octogenarians, a new study shows.

And a small but disturbing pattern showed up in those who took the herb extract during the three-year study, the researchers added.

"Seven had TIAs (transient ischemic attacks, or mini-strokes) or stroke," said study author Dr. Hiroko Dodge, an assistant professor of public health at Oregon State University. Exactly why this happened requires further study, she added.

Ginkgo biloba is believed to have antioxidant and anti-inflammatory properties, protecting cell membranes and helping govern the workings of the brain's chemical messengers, or neurotransmitters. Some studies have found that the herb may help some people with Alzheimer's disease.

Dodge's team evaluated 118 men and women aged 85 and older who were all free of memory complaints at the start of the study. They scored normally on a memory function test before being admitted to the study. Half were assigned to take 240 milligrams of ginkgo biloba extract daily; half got a placebo.

Overall, Dodge found that 21 people developed mild memory problems during the study -- 14 took placebo, and 7 took the ginkgo supplement. "There was a clear tendency that ginkgo prevents memory decline," but the differences in the preservation of memory between the two groups were not statistically significant, she said.

But when the researchers did a secondary analysis, taking into account the level of medication adherence, those who actually remembered to take the extract did show some benefit. "Those taking the ginkgo extract [on a regular basis] had a 70 percent lower risk of developing mild memory problems than those taking placebo," she said.

It is not clear whether the difference is a chance occurrence or not.

"We have to wait for larger studies," Dodge said.

More research is also needed, she said, on why the 7 participants who had strokes or mini-strokes were all on the extract and what that association might be.

Another expert agreed, calling the findings inconclusive.

"The study was really too small to provide conclusive results on the benefits and risks of ginkgo supplement," said Dr. Paul Aisen, director of the Alzheimer's Disease Cooperative Study at the University of California, San Diego.

"Without a larger study, I would certainly not recommend the use of ginkgo biloba extract in those 85 and over," he said. Overall, he added, the bulk of studies published in the medical literature do not provide enough proof to recommend the herb for preserving memory and cognitive function.

Likewise, the Alzheimer's Association says on its Web site that while the herb may help some people with Alzheimer's disease, further research is needed to find the exact way in which it works. Experts are awaiting the results of a much larger, multi-center trial based at the University of Pittsburgh. That trial compared the effects of the herb with a placebo in 3,000 people to see if ginkgo biloba helped prevent or delay the onset of Alzheimer's disease. The trial ran through 2007, and the results will not be available until some time later.

Dodge's study is published in the Feb. 27 online issue of Neurology.

More information

To learn more about alternative treatments for Alzheimer's, visit the Alzheimer's Association.



SOURCES: Hiroko Dodge, Ph.D., assistant professor, public health, Oregon State University, Corvallis; Paul Aisen, M.D., director, Alzheimer's Disease Cooperative Study, and professor, neuroscience, University of California, San Diego; Feb. 27, 2008, Neurology online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Fish Oil Might Help Relieve MS
2. HIV Drug Might Fight Cancer
3. High and mighty: first common height gene identified by researchers behind obesity gene finding
4. Vitamin C Plus Fat Might Spur Cancer
5. Mathematics might save you a trip to the ER
6. Veggies Might Ward Off Age-Linked Vision Woes
7. Rating your pain from 0 to 10 might not help your doctor
8. Blood Marker Might Help Spot Early Liver Cancer
9. Hushed Genes Might Mean Higher Lung Cancer Risk
10. Mathematics might save you a trip to the ER
11. More Prostate Cancers Might Be Prevented
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Ginkgo Biloba Might Not Preserve Memory in Octogenarians
(Date:2/11/2016)... ... February 11, 2016 , ... According to an article published February ... loss dietary supplement, is being recalled due to the discovery that it contains dangerous ... not a single supplement on the market proven to help people safety lose excess ...
(Date:2/11/2016)... , ... February 11, 2016 , ... Registered nurses, licensed ... CEU seminar titled, “Stroke Management: Time to Act, Time to Heal” on Thursday, February ... in Whippany, N.J. The presenter is Vishal Chedda, president of ANSA Consultants, who will ...
(Date:2/11/2016)... (PRWEB) , ... February 12, 2016 , ... The ... is up from 0.416 in 2013. The SJR uses data taken from the Scopus ... account both the number of citations received by the journal over a three year ...
(Date:2/11/2016)... ... 11, 2016 , ... The Chartis Group, a national advisory ... in the “2015/2016 Best in KLAS: Software and Services” report in two categories: ... and insights firm on a global mission to improve healthcare delivery by amplifying ...
(Date:2/11/2016)... ... February 11, 2016 , ... Thermi™, a world leader ... to announce the promotions of Allison Kelly to executive vice president of the ... vice president of North American capital sales, and Wendy Oseas to vice president ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... SAN FRANCISCO , Feb. 11, 2016 Potrero ... system, is pleased to announce the appointment of George ... San Antonio, TX , WellMed is ... servicing over 200,000 patients and HMO members in ... founding WellMed in 1990 out of his own internal medicine ...
(Date:2/11/2016)... Feb. 11, 2016  MiMedx Group, Inc. (NASDAQ: ... amniotic membrane and other birth tissues, human skin and ... and market advanced products and therapies, announced today that ... Global Healthcare Conference in New York ... Michael J. Senken , Chief Financial Officer and ...
(Date:2/11/2016)...  AfterPill.com is reporting that this week,s Centers for ... women who are at risk of unintended pregnancy impacts ... raises the risks of unprotected sex in particular.  ... to the Guttmacher Institute, there are 43 million women ... who have sex without the intention of becoming pregnant.  ...
Breaking Medicine Technology: