Navigation Links
Getting rid of old mitochondria
Date:6/16/2014

It's broadly assumed that cells degrade and recycle their own old or damaged organelles, but researchers at University of California, San Diego School of Medicine, The Johns Hopkins University School of Medicine and Kennedy Krieger Institute have discovered that some neurons transfer unwanted mitochondria the tiny power plants inside cells to supporting glial cells called astrocytes for disposal.

The findings, published in the June 17 online Early Edition of PNAS, suggest some basic biology may need revising, but they also have potential implications for improving the understanding and treatment of many neurodegenerative and metabolic disorders.

"It does call into question the conventional assumption that cells necessarily degrade their own organelles. We don't yet know how generalized this process is throughout the brain, but our work suggests it's probably widespread," said Mark H. Ellisman, PhD, Distinguished Professor of Neurosciences, director of the National Center for Microscopy and Imaging Research (NCMIR) at UC San Diego and co-senior author of the study with Nicholas Marsh-Armstrong, PhD, in the Department of Neuroscience at Johns Hopkins University and the Hugo W. Moser Research Institute at Kennedy Krieger Institute in Baltimore.

"The discovery of a standard process for transfer of trash from neuron to glia will most likely be very important to understanding age-related declines in function of the brain and neurodegenerative or metabolic disorders," Marsh-Armstrong said. "We expect the impact to be significant in other areas of biomedicine as well."

The researchers looked specifically at the axons of retinal ganglion cells in mice, a type of neuron that transmits visual information from the eye to the brain. The investigation was prompted by observations by Marsh-Armstrong while studying a mouse model of glaucoma that protein products from the retina were accumulating in the optic nerve head (ONH) just
'/>"/>

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Study: Women not getting enough exercise; at risk of developing metabolic syndrome
2. HPV vaccine completion rate among girls is poor, getting worse
3. American Kids Getting Fewer Prescription Drugs: Study
4. Getting your message across
5. Cholesterol Levels Getting Better for U.S. Kids: CDC
6. Kids need at least 7 minutes a day of vigorous physical activity, but most arent getting that
7. U.S. Kids Getting Enough Sleep After All: Survey
8. Fitquip: Getting Fit for Christmas on the Beach
9. New Blog Post from iHealthology.com Announces Why Staying Fit Means Getting on the Move
10. Quorn Foods Inc. Releases a Statement Following an Article on Getting the Most Out of a Vegetarian Healthy Food Diet
11. People with diabetes in Ontario getting fewer government-funded eye exams, new study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Getting rid of old mitochondria
(Date:12/17/2014)... get more fruits and vegetables at school than they do ... is true for students from wealthier families. These findings ... a healthy boost to poor students, diets, according to the ... students all ate a similar amount of fruits and vegetables ... recently in the journal Preventive Medicine . ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, 2014 (HealthDay ... work commitment is a big reason why, new research suggests. ... Mathias Basner, an assistant professor of sleep and chronobiology in ... A time-use survey of nearly 125,000 Americans, ages 15 ... exchanged for sleep. Short sleepers -- those who slept six ...
(Date:12/15/2014)... December 15, 2014 Main Street Dental ... is weighing in on a new study providing evidence ... the oral hygiene of children. , Sufficient enough evidence ... such as pop or juice drinks, with the onset ... however, is whether drinks listed as 100% fruit juice, ...
(Date:12/15/2014)... 2014 Health Dialog, a leading ... that it has received Patient Oriented Accreditation from ... its Disease Management (DM) Programs for asthma, congestive ... heart disease and diabetes. This marks the 12th ... Dialog’s Disease Management (DM) Programs, reaffirming Health Dialog’s ...
(Date:12/15/2014)... 15, 2014 Kathy McAfee, America's Marketing ... World Awards in the category of Best Blog 2014. ... for her weekly career blog Networking Ahead ... help professionals elevate their talent and influence through better ... after her book Networking Ahead for Business, has been ...
Breaking Medicine News(10 mins):Health News:Poor Students Eat Healthier Foods at School, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:Main Street Dental Team, Unionville’s Most Innovative Dental Clinic, Comments on New Study Relating Pure Fruit Juice to Poor Oral Hygiene 2Health News:Health Dialog Receives NCQA Accreditation for Disease Management Programs 2Health News:Kathy McAfee, America’s Marketing Motivator, Wins Best Blog from Women World Awards 2
... Amerigroup Corporation (NYSE: AGP ) today announced ... Conference on November 12 in Phoenix, Arizona. , A live webcast ... p.m. Eastern Time, can be accessed on Amerigroup,s Web site, ... of the webcast will be available for 30 days after the ...
... they occur , TUESDAY, Nov. 3 (HealthDay News) -- ... they actually experience, a new study finds. , The ... assess their levels of neuroticism and depression. For the ... they felt any of 15 common physical symptoms, including ...
... stage small cell lung cancer(LSCL) with a combination of ... opening the door to larger scale investigation, according to ... Anderson Cancer Center. The Phase II study was ... the annual meeting of the American Society for Radiation ...
... Provista ... of breast cancer. , ... AZ (PRWEB) November 3, 2009 -- A healthy 44-year-old woman will celebrate many future birthdays ... cancer., , ,Dr. Sweeten, a board-certified gynecologist and Fellow of the American College of Obstetricians ...
... , RONKONKOMA, N.Y., Nov. 3 NBTY, Inc. (NYSE: NTY ... marketer of nutritional supplements, today announced it will web cast a ... web site, ( www.NBTY.com ), on Monday, November 9, ... for the fiscal fourth quarter results will be issued at 4:00 ...
... , PARK RIDGE, Ill. and CHICAGO, Nov. 3 To ... the national debate on healthcare reform, the LIFE ... be hosting a public forum on "Ethics and Healthcare Reform" ... Edison Park Lutheran Church , 6626 N. Oliphant Ave., ...
Cached Medicine News:Health News:Depression May Blur Memory of Aches and Pains 2Health News:Study of concurrent radiotherapy, chemotherapy shows promise in small cell lung cancer 2Health News:Study of concurrent radiotherapy, chemotherapy shows promise in small cell lung cancer 3Health News:A Breast Cancer Test That Saves Lives 2Health News:A Breast Cancer Test That Saves Lives 3Health News:NBTY to Web Cast Fiscal Fourth Quarter Conference Call 2Health News:Ethics and Healthcare Reform Panel, Community Forum Open to Public November 17 2Health News:Ethics and Healthcare Reform Panel, Community Forum Open to Public November 17 3
(Date:12/15/2014)... 12, 2014 Research and Markets ( ... "Inferior Vena Cava (IVC) Filters - Global Trends, Estimates ... http://photos.prnewswire.com/prnh/20130307/600769 Global ... reach US$435 million by 2016. The North ... the global value while Europe ...
(Date:12/15/2014)... BRIDGEWATER, N.J. , Dec. 15, 2014 /PRNewswire/ ... (EURONEXT: SAN and NYSE: SNY) are collaborating with nationally-recognized ... Cholesterol Counts , an awareness program that will gauge ... the risks associated with high LDL-C (bad cholesterol).  American ... to take a brief poll and answer a ...
(Date:12/15/2014)... --  DaVita HealthCare Partners Inc.  (NYSE: ... most innovative health care communities, today announced that ... Research  (DCR) and  HealthCare Partners Clinical Research , will ... research and data analytics services, specifically in patients ... disease (ESRD), as well as primary care and ...
Breaking Medicine Technology:Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 2Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 3Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 2Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 3Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 5Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 6DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 2DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 3DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 4
... 2011 Pharmatek Laboratories, Inc., a premier contract ... announced that it has added spray drying to ... has purchased a Buchi B-290 Mini Spray Dryer ...  This technology can be used for both oral ...
... (NASDAQ: STXS ) today announced that executive management ... The Deutsche Bank Annual Health Care Conference ... of Stereotaxis, is scheduled to present an overview of the ... The JMP Securities Annual Research Conference in San Francisco. ...
Cached Medicine Technology:Pharmatek Laboratories Adds Spray Drying to Drug Development Services 2Stereotaxis to Present at Upcoming Investor Conferences 2Stereotaxis to Present at Upcoming Investor Conferences 3
Used following hysterectomy procedure. Often attached to Bard bile bag....
Single round silicone drain with 10 in. hole pattern, 49 in. long...
Hubbed drains are made of translucent silicone and include a full-length X-ray opaque stripe....
... For Excellent Drainage PLUS Greater Patient ... BLAKE Drains are white, radiopaque silicone drains ... a solid core center. Their other components ... extension tubing and an adapter. The drains ...
Medicine Products: