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Getting forgetful? Then blueberries may hold the key
Date:4/10/2008

If you are getting forgetful as you get older, then a research team from the University of Reading and the Peninsula Medical School in the South West of England may have good news for you.

They have found that phytochemical-rich foods, such as blueberries, are effective at reversing age-related deficits in memory, according to a study soon to be published in the science journal Free Radical Biology and Medicine. The researchers working at the Schools of Food Biosciences and Psychology in Reading and the Institute of Biomedical and Clinical Sciences at the Peninsula Medical School in Exeter supplemented a regular diet with blueberries over a 12-week period, and found that improvements in spatial working memory tasks emerged within three weeks and continued throughout the period of the study.

Blueberries are a major source of flavonoids, in particular anthocyanins and flavanols. Although the precise mechanisms by which these plant-derived molecules affect the brain are unknown, they have been shown to cross the blood brain barrier after dietary intake. It is believed that they exert their effects on learning and memory by enhancing existing neuronal (brain cell) connections, improving cellular communications and stimulating neuronal regeneration.

The enhancement of both short-term and long-term memory is controlled at the molecular level in neurons. The research team was able to show that the ability of flavonoids to induce memory improvements are mediated by the activation of signalling proteins via a specific pathway in the hippocampus, the part of the brain that controls learning and memory.

This innovative research was conducted by a multidisciplinary research team led by Dr. Jeremy Spencer, a lecturer in Molecular Nutrition at the University of Reading and included Dr. Claire Williams, a Psychologist also from Reading and Dr. Matt Whiteman, a Principal Investigator at the Institute of Biomedical and Clinical Science, Pe
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Contact: Andrew Gould
media@pr-works.co.uk
44-139-268-6107
The Peninsula College of Medicine and Dentistry
Source:Eurekalert

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