Navigation Links
Getting a cancer drug to patients takes both scientific and business smarts
Date:1/23/2014

sive knowledge of biochemistry. But it also demands business sense: to negotiate financial agreements with biotech companies that have expertise to construct the delivery system. Specialized components include synthetic antibodies that are specifically engineered to seek out HER-2-positive cancer cells, as well as "linkers" that would fuse the toxin to the antibodies as a space capsule might be attached to a booster rocket until just the moment when, inside the cell, the toxin detonates.

If the product ultimately works, each of these companies will see a share of what could be substantial profits. Those financial details, and many others, are essential parts of the business plan, and need to be worked out now. Sinha and his team would then take the completed plan to venture capitalists and large foundations which he hopes he and his team can convince to put up the capital needed to fund both the manufacturing process and the all-important human clinical trials that would follow.

Attacking HER-2-positive breast cancer may be just the start. If, as Sinha expects, the toxin can also be combined with different antibodies that seek out other cancers, Sinha says the drug has "nearly endless" cancer fighting potential.

"He is a very impressive young man," says Joseph Bertino, chief scientific officer at the Rutgers Cancer Institute of New Jersey and a professor of medicine and pharmacology at Rutgers Robert Wood Johnson Medical School.

Bertino, whose own research focuses on targeted cancer therapies, is one of several Rutgers faculty members who have advised Sinha. "He has collaborators lined up," Bertino adds, "and I think he has a real shot at it." Sinha and his team have formed a company, OncoLinx LLC, to help advance their plans.

Sinha's foray into the business side of drug development is a sign of rapidly changing times. In the past, nearly all who earned doctorates in the biomedical sciences stayed in academia. B
'/>"/>

Contact: Rob Forman
robert.forman@rutgers.edu
973-972-7276
Rutgers University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Study: Women not getting enough exercise; at risk of developing metabolic syndrome
2. HPV vaccine completion rate among girls is poor, getting worse
3. American Kids Getting Fewer Prescription Drugs: Study
4. Getting your message across
5. Cholesterol Levels Getting Better for U.S. Kids: CDC
6. Kids need at least 7 minutes a day of vigorous physical activity, but most arent getting that
7. U.S. Kids Getting Enough Sleep After All: Survey
8. Fitquip: Getting Fit for Christmas on the Beach
9. New Blog Post from iHealthology.com Announces Why Staying Fit Means Getting on the Move
10. Quorn Foods Inc. Releases a Statement Following an Article on Getting the Most Out of a Vegetarian Healthy Food Diet
11. People with diabetes in Ontario getting fewer government-funded eye exams, new study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Getting a cancer drug to patients takes both scientific and business smarts
(Date:6/30/2015)... ... June 30, 2015 , ... Ticket Down is a reliable source for last minute ... band has been packing stadiums across North America in conjunction with their 2015 “Zip Code ... the energy of a band in their twenties. Some of the most beloved songs ...
(Date:6/30/2015)... ... June 30, 2015 , ... The board ... a ‘responsive design’ website to inform potential sinus surgery patients about ear, nose, ... website includes information about a wide variety of ENT issues including hearing loss, ...
(Date:6/30/2015)... ... ... The Blue Cross and Blue Shield of Minnesota Foundation today announced the award ... community health by focusing on the social and economic factors that greatly affect health ... year in 2016 based on progress in 2015. , “We took a new approach ...
(Date:6/30/2015)... ... June 30, 2015 , ... Villa Health Care Center is ... the country. To spread the word, Villa Health Care Center created a video, ... worthy of five stars. While Medicare centers its rating on health inspections, staffing, ...
(Date:6/30/2015)... ... June 30, 2015 , ... ... video, “Fireside Convalescent Care Center.” The video informs community members of Fireside’s Five-Star ... seeing the need for those seeking care to be well informed and confident ...
Breaking Medicine News(10 mins):Health News:The Rolling Stones Tickets in Raleigh at Carter Finley Stadium: Ticket Down Offers Last Minute Tickets for the Rolling Stones and Avett Brothers in Raleigh 2Health News:Clear Lake Medical Center ENT Launches ‘Responsive Design’ Website 2Health News:Clear Lake Medical Center ENT Launches ‘Responsive Design’ Website 3Health News:Blue Cross and Blue Shield of Minnesota Foundation Awards $1.5 Million 2Health News:Villa Health Care Center Announces Highest Care Rating in New Video 2Health News:Fireside Convalescent Hospital Proves Itself as a Leading Care Center in New Video 2
... be considered essential elements of a multidisciplinary approach to ... diagnosis. However, for women suffering from breast cancer in ... around the world, this fundamental area of patient care ... issues, many of the world,s leading breast cancer experts ...
... diagnosing malaria is essential for effective and life-saving ... is not always possible because current methods are ... microscopic analysis. Now, a promising new optical imaging ... the Optical Society,s (OSA) open-access journal Biomedical ...
... University of Cincinnati (UC) have received a four-year, $3.7 ... investigations into circadian rhythms that could lead to enhanced ... performance. The research will be conducted by an ... professor in the department of molecular and cellular physiology. ...
... 17 (HealthDay News) -- Pregnant women who are overweight ... for pregnancy complications, a new study shows. These women ... normal blood sugar or those with gestational diabetes and normal ... pregnant women who are obese or have gestational diabetes, and ...
... Michigan State University surgeon is teaming up with a Lansing-area ... simple, cost-effective saliva test to detect oral cancer, a breakthrough ... dying of the world,s sixth most common cancer. Barry ... of Surgery and lead investigator on the project, is working ...
... , , , , ... AUDIO: New research in half siblings adds to evidence that even though autism ... Click here for more information. , , , ... , , , , , ...
Cached Medicine News:Health News:International breast health global summit will focus on supportive care and quality of life 2Health News:International breast health global summit will focus on supportive care and quality of life 3Health News:Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis 2Health News:Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis 3Health News:University of Cincinnati researchers win $3.7M grant from US Department of Defense 2Health News:Overweight Pregnant Women at Higher Risk for Complications 2Health News:Saliva test could dramatically increase detection of oral cancer 2Health News:Study of half siblings provides genetic clues to autism 2Health News:Study of half siblings provides genetic clues to autism 3Health News:Study of half siblings provides genetic clues to autism 4Health News:Study of half siblings provides genetic clues to autism 5
(Date:6/30/2015)... CARLSBAD, Calif. , June 30, 2015 /PRNewswire/ ... Inc. company (Nasdaq: NTK ) and a ... smart control markets, today announced it acquired mobile ... assets from privately held Numera, Inc. ... Numera creates best-in-class, easily implemented, mobile PERS products ...
(Date:6/30/2015)... June 30, 2015   Millar, Inc. , a ... announced the 2016 retirement of Craig Thummel , ... 12 years of service to the Company. The Company ... senior members of the Executive Management team as his ... Daugherty , currently Director of Sales and Marketing, as ...
(Date:6/30/2015)... Research and Markets( ... "Global Array Instruments Market 2015-2019" report ... instruments market to grow at a CAGR of ... global array instruments market can be divided into ... including tissue microarrays and cell microarrays. This report ...
Breaking Medicine Technology:Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 2Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 3Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 4Millar, Inc. Announces Leadership Changes 2Millar, Inc. Announces Leadership Changes 3Global Array Instruments Market 2015-2019 - Advances in Personalized Medicines with Affymetrix, Agilent Technologies & Illumina Dominating 2
... Princeton HealthCare System (PHCS) ( www.princetonhcs.org ) will conduct its ... hosts a discussion about women,s pelvic floor disorders and treatment ... p.m. and can be joined by going to the PHCS ... has enormous potential for sharing information about health issues," said ...
... BEVERLY HILLS, Calif., Sept. 20 Waismann Method ... the first-ever National Take-Back Initiative, organized by the U.S. ... to encourage the public to surrender expired, unwanted or ... heels of recent reports that prescription drug abuse and ...
Cached Medicine Technology:First Live Web Chat by New Jersey's Princeton HealthCare System Focuses on Women's Health 2Waismann Method Supports National Take-Back Initiative 2Waismann Method Supports National Take-Back Initiative 3
... a smooth, flat tip extending from the ... uniquely designed tip is used to efficiently ... the posterior capsule. The end opening ... sideports help avoid surge should the end ...
... model CQ2015, combines the best of foldable ... contains a Collamer optic with modified "C" ... loops offer flexibility comparable to polypropylene and ... superior "shape memory". The light patterns associated ...
... of CLS restores the patients Quality of ... the patient is not physically active. Cylos ... detection and restoration of hemodynamics in Atrial ... management via Home monitoring in combination with ...
The Victory single- and dual-chamber rate-responsive pacemakers from St. Jude Medical are advanced-feature systems, designed to save valuable clinic time, maximize patient safety, and provide other t...
Medicine Products: