Navigation Links
Gestational diabetes linked to increased risk for heart disease in midlife
Date:3/12/2014

OAKLAND, Calif. Women who experience gestational diabetes may face an increased risk of early heart disease later in life, even if they do not develop type 2 diabetes or metabolic syndrome subsequent to their pregnancy, according to a Kaiser Permanente study published today in the Journal of the American Heart Association.

"Our research shows that just having a history of gestational diabetes elevates a woman's risk of developing early atherosclerosis before she develops type 2 diabetes or metabolic syndrome," said Erica P. Gunderson, PhD, MPH, study lead author and senior research scientist in the Kaiser Permanente Division of Research in Oakland, Calif. "Pregnancy has been under-recognized as an important time period that can signal a woman's greater risk for future heart disease. This signal is revealed by gestational diabetes."

Gestational diabetes, a condition of elevated blood sugar during pregnancy, usually disappears after the pregnancy. It is managed with meal planning, activity and sometimes insulin or other medications.

In the 20-year study, researchers assessed risk factors for heart disease before pregnancy among 898 women, 18 to 30 years old, who later had one or more births. The women were periodically tested for diabetes and metabolic conditions before and after their pregnancies. Using ultrasound, researchers measured the thickness of the walls of participants' carotid artery, which circulates blood to the neck and face. Carotid artery wall thickness is an early measure of atherosclerosis plaque build-up in arteries and predicts heart attack and stroke in women. The artery's thickness was measured on average 12 years after pregnancy.

Researchers found a larger average carotid artery wall thickness in study participants with a history of gestational diabetes who did not develop diabetes or metabolic syndrome during the 20-year follow-up compared to those who never experienced gestational diabetes.. The difference was not attributed to obesity or other risk factors for heart disease that were measured before pregnancy.

It's important to recognize reproductive characteristics that may contribute to disease risk in women, Gunderson said. "It's a shift in thinking about how to identify a subgroup at risk for atherosclerosis early. The concept that reproductive complications unmask future disease risk is a more recent focus. It may inform early prevention efforts."

This study is part of Kaiser Permanente's ongoing efforts to better understand gestational diabetes. Last year, Kaiser Permanente researchers found that pre-pregnancy obesity and older maternal age are among the risk factors for delayed lactation for women with gestational diabetes.

Kaiser Permanente can conduct transformational health research in part because it has the largest private patient-centered electronic health system in the world. The organization's electronic health record system, Kaiser Permanente HealthConnect, securely connects 9.1 million patients to more than 16,000 physicians in almost 600 medical offices and 38 hospitals. It also connects Kaiser Permanente's research scientists to one of the most extensive collections of longitudinal medical data available, facilitating studies and important medical discoveries that shape the future of health and care delivery for patients and the medical community.


'/>"/>

Contact: Jennifer Schell
jschell@golinharris.com
202-585-2612
Kaiser Permanente
Source:Eurekalert

Related medicine news :

1. Phone contact with nurses linked with better outcomes for women with gestational diabetes
2. Gestational exposure to urban air pollution linked to vitamin D deficiency in newborns
3. Gestational Diabetes, Poverty Linked to ADHD
4. UMSOM dean urges caution in revising diagnostic guidelines for gestational diabetes
5. Study confirms recurrence of small-for-gestational-age pregnancies
6. Independent panel to present findings on diagnosing gestational diabetes mellitus
7. Task Force: Screen for Gestational Diabetes After 24 Weeks of Pregnancy
8. Genetic link to gestational diabetes
9. New report shows diagnosed diabetes, pre-diabetes, and gestational diabetes is on the rise among privately insured Americans
10. How a cancer drug leads to diabetes
11. Heart failure patients with diabetes may benefit from higher glucose levels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2017)... ... , ... Providing broad access to life-saving drugs and rewarding the innovators who ... to address this problem. , That was the message from Dana Goldman, PhD, Leonard ... University of Southern California, who served as the keynote speaker for Western University of ...
(Date:4/21/2017)... ... April 21, 2017 , ... Evoke ... young adults, has kicked off its 4th annual Forum for Innovative Treatment Solutions ... is “Attachment Informed Therapy for Mental Health and Addiction.” , FITS’ 2017 ...
(Date:4/21/2017)... ... April 21, 2017 , ... The adage “Show, don’t ... the next project in the company’s esteemed VISION House demonstration project series. Manifesting the ... the amount of resources they need to live affordably and abundantly without unduly taxing ...
(Date:4/21/2017)... ... April 21, 2017 , ... Crossover Symmetry , ... , an active lifestyle company that provides Human Performance Training and education to ... offers, first responders, military officers and others in service through the development and ...
(Date:4/21/2017)... ... April 21, 2017 , ... Northern California Medical ... Care Spring Symposium on April 1, 2017 in Santa Rosa. This well-attended annual ... healthcare providers an opportunity to learn about cutting edge treatments, to collaborate, share ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 2017 /PRNewswire/ - CRH Medical Corporation (TSX: CRH) (NYSE MKT: CRHM) (the "Company"), ... Healthcare Investor Conference 2017 at the Sheraton Hotel in ... Executive Officer of the Company is scheduled to present on Tuesday, ... and the Chairman of the Board, Tony Holler ... ...
(Date:4/19/2017)... 2017 Global Surgical Drainage Device Market: Overview ... to remove excess liquid and air. The fluid to ... or lymph. Surgical drains are used in a wide ... surgery, cardiovascular surgery, neurosurgery, plastic surgery etc. Common use ... accumulation of fluid e.g. blood or pus. Surgical drains ...
(Date:4/19/2017)... 19, 2017  Sorrento Therapeutics, Inc. (NASDAQ: ... company developing new treatments for cancer and other ... its previously announced underwritten public offering of 23,625,084 ... offering price of $2.00 per share, before deducting ... payable by Sorrento.  The net proceeds to Sorrento ...
Breaking Medicine Technology: