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Georgia physicians' study published in the Journal of Urology
Date:2/27/2013

a disease-free survival (DFS) calculation with a PSA<0.2. The surgical definition is much stricter than the one usually used in radiation therapy studies. Results showed comparable DFS at 10 (75 percent, 77 percent, 77 percent) and 15 years of follow up (73 percent, 68 percent, 75 percent). A sub analysis of patients treated with transperineal implants between 1995 and 2000 showed a 15 year disease-free survival (DFS) of 79 percent.

The analysis includes over 300 men whose prostate cancer recurred who were treated 16-25 years ago. Recurrences were PSA defined and results showed the majority of recurrences occurred within the first five years after treatment and no recurrences were noted15.5-25 years after treatment.

This study concludes that follow up evaluations are necessary for 15 years after treatment to fully understand the outcomes of any treatment for prostate cancer. Unlike a previous study on patients recurring after prostatectomy, this is the first to include interval censoring analysis when looking at time to recurrence. If a man's PSA is <0.20 ng/ml 15 years post treatment, later recurrence of the disease should be rare.


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Contact: Logan Moses
LMoses@golinharris.com
404-367-2743
Radiotherapy Clinics of Georgia
Source:Eurekalert

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