Navigation Links
George Mason University research gives hope to women with deadliest breast cancer
Date:11/14/2011

Women with the deadliest and rarest form of breast cancer now have a chance of treatment where once their options were severely limited, thanks to a new discovery by George Mason University researchers.

This aggressive cancer, called "inflammatory breast cancer," kills about half the women who have it within five years; patients live on average a mere 18 months after diagnosis. About 10,000 women are diagnosed each year with inflammatory breast cancer, according to U.S. government statistics.

In a recent study, Mason scientists pinpointed a key driver in the cancer that is leading to new ways to treat it. This study is not only a success for cancer patients but for a pioneering research method that discovered the finding as well, says Emanuel "Chip" Petricoin, co-director of Mason's Center for Applied Proteomics and Molecular Medicine (CAPMM) along with Lance Liotta.

This summer, doctors at Philadelphia's Fox Chase Cancer Center under the direction of Massimo Cristofanilli, the center's chair of medical oncology, began treating inflammatory breast cancer patients with a drug originally developed for non-small cell lung cancer because Mason research revealed a commonality between the two cancers. Prior to the research, these breast cancer patients had limited treatment options, Petricoin says.

Discovering how the cancer works using proteomics, an approach that looks at the proteins on the genes, was essential to the finding. If researchers had stuck with traditional genome analysis, they would have missed the protein that can be targeted to treat this particularly dangerous form of breast cancer, Petricoin says. The proteins on the genes are the key for successful treatment.

"It is the proteins that the drug targets, not the genes," he says.

Petricoin and Liotta invented a technology called the reverse phase protein array a decade ago, which Mason exclusively licensed to Theranostics Health, Inc, a comp
'/>"/>

Contact: Michele McDonald
mmcdon15@gmu.edu
703-993-9511
George Mason University
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Georgetown researchers examine 21-year series of nipple sparing mastectomy cases and find no cancers
2. FDA awards Georgetown University a Center of Excellence in Regulatory Science & Innovation
3. Georgetown research identifies key reasons racial disparities exist in emergent stroke treatment
4. Cedars-Sinais mobile medical clinics receive grant from George Hoag Family Foundation
5. FDA and Georgetown University Medical Center announce partnership
6. George to receive GSAs 2010 Distinguished Career Contribution to Gerontology Award
7. George Carter of Carter's Plumbing & Rooter Announces the Launch of His New Website, CartersPlumbingRedondoBeach.com
8. Life sciences research grants awarded through Inova Health System and George Mason University
9. Georgetown Research Center Helps Reporters Decipher Health Reform Law & Impact on State Residents
10. Georgetown University Center for Children and Families Hails Health Reform As Big Win for Children and Families
11. George Lundberg, MD, Joins MedPage Today(R) as Editor-at-Large
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... May 24, 2013 The nation’s first ... Intuitive Surgical Inc.’s da Vinci Surgical System concluded yesterday, ... a Washington State Court jury ruled in a 10-to-2 ... a surgeon who performed a da Vinci prostatectomy on ... patient’s family had alleged in their lawsuit that the ...
(Date:5/24/2013)... 24, 2013 Mr. Brian Su, CEO ... Annual EB-5 Investment Summit: Dealmakers Conference in Long Beach, ... focus on exploring alternative finance through EB-5 immigrant investors ... and economic information, and updates to project developers, regional ... industry. , "Our goal is to assist EB-5 ...
(Date:5/24/2013)... Two mutations central to the development of infantile myofibromatosis ... bone, and soft tissuemay provide new therapeutic targets, according ... Mount Sinai. The findings, published in the American ... treatment options for this debilitating disease, for which the ... the tumors. , IM is an inheritied disorder that ...
(Date:5/24/2013)... 2013 Dwell Media LLC ... as Executive Vice President of Digital for Dwell Media. ... represented a large portion of Yahoo's global media business. ... develops a fully-integrated commerce unit to launch in 2014. ... digital content for leading firms in Silicon Valley. Dwell, ...
(Date:5/24/2013)... BestSatelliteProviders.com the online satellite TV and ... compare the features and services offered by leading ... the rankings of the best rural Internet ... on their website. , BestSatelliteProviders.com – ... Matthews, the spokesperson for BestSatelliteProviders.com, “When consumers were ...
Breaking Medicine News(10 mins):Health News:Da Vinci Robot Lawsuit News: Bernstein Liebhard LLP Comments on Verdict in Nation’s First Trial Involving Alleged Da Vinci Complications 2Health News:Da Vinci Robot Lawsuit News: Bernstein Liebhard LLP Comments on Verdict in Nation’s First Trial Involving Alleged Da Vinci Complications 3Health News:Brian Su Organizes 3rd Annual EB-5 Investment Conference in Long Beach, California 2Health News:Researchers identify first drug targets in childhood genetic tumor disorder 2Health News:Yahoo Commerce Head Joins Leadership at Dwell Media 2Health News:Best Rural Internet Service Provider in 2013 by BestSatelliteProviders.com 2
... , ALEXANDRIA, Va., Oct. 28 The same reassuring voice ... poison emergency may be the same person answering your questions ... centers are among the first responders helping America respond to ... a variety of ways. , A few examples: , ...
... microorganisms, and microbial cells found in the human gut are ... However, little is known about the ways in which ... That is why gastroenterologists at Rush University Medical Center ... U.S. Department of Defense to chart the presence of microorganisms ...
... reduce eyestrain, poor posture, study finds , WEDNESDAY, Oct. ... help reduce the level of pain linked to poor ... shouldn,t just assume that problems will be solved by ... chairs. It,s also important to make sure the furniture ...
... Sciences, Inc. (OTC Bulletin Board: DSCI), a specialty medical ... announced today that the Food and Drug Administration has ... the Company,s BIOGUARD(TM) barrier gauze wound dressings as Class ... its initial market clearance on February 25, 2009, via ...
... BLOOMINGTON, Minn., Oct. 28 The Child Neurology Foundation ... Spasms Awareness Week (October 11-17) that will go towards ... of epilepsy. , "Due to its rare nature, ... as it should be," said Lawrence Brown, M.D., Associate ...
... , WEDNESDAY, Oct. 28 (HealthDay News) -- Letting children sleep ... overweight or obese, a new study suggests. , Researchers ... tended to be heavier (as measured by body mass index, ... who slept less than eight hours a night, those who ...
Cached Medicine News:Health News:American Association of Poison Control Centers: Count U.S. Poison Centers Among First Responders in H1N1 Flu Pandemic 2Health News:Gastroenterologists explore relationship between bacteria in the gut and breast cancer 2Health News:Gastroenterologists explore relationship between bacteria in the gut and breast cancer 3Health News:Takes a Pro to Make Offices Pain-Free 2Health News:FDA Issues Guidance for Derma Sciences' Exclusive Wound Dressing With pDADMAC 2Health News:FDA Issues Guidance for Derma Sciences' Exclusive Wound Dressing With pDADMAC 3Health News:FDA Issues Guidance for Derma Sciences' Exclusive Wound Dressing With pDADMAC 4Health News:Child Neurology Foundation Announces $30,000 Grant for Research Into Cause and Treatment of Infantile Spasms 2Health News:Child Neurology Foundation Announces $30,000 Grant for Research Into Cause and Treatment of Infantile Spasms 3Health News:Let Kids Sleep Late on Weekends to Fight Fat: Study 2Health News:Let Kids Sleep Late on Weekends to Fight Fat: Study 3
(Date:5/23/2013)... 2013  A recently published clinical study conducted at ... , demonstrates that 3D mammography (breast tomosynthesis) significantly ... The study, "Implementation of Breast Tomosynthesis in ... by Stephen L. Rose , MD, ... American Journal of Roentgenology (AJR). The AJR is ...
(Date:5/23/2013)... -- More than half of women diagnosed with early ... still have excellent outcomes. To educate women, Agendia, Inc. ... sources of online consumer information about breast cancer genomic ... recently diagnosed women with information sources, to help them ... "We anticipate these innovative social media campaigns will encourage ...
(Date:5/23/2013)... May 23, 2013  Every day, their baby stopped breathing, ... his lungs. April and Bryan Gionfriddo ... true. "Quite a few doctors said he had ... April Gionfriddo , about her now 20-month-old ... would work, we would take it and run with it." ...
Breaking Medicine Technology:First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 2First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 3Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 3Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 2Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 3Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 4
... inserts are an ophthalmologic medical device designed ... from -1.00 to -3.00 diopters.* When placed ... patient's central optical zone, the product reshapes ... inserts is composed of two prescription inserts, ...
... the hearts of cardiologists and cardiac patients ... operative words for Heartline™. Patients conduct normal, ... and their attending physician know that a ... heart condition is only a phone call ...
... the physician a new approach to supportive eye ... weight simply uses gravity to gently close the ... when the eyelid muscle is relaxed. MedDev ... of skin tone colors to match a patients ...
... The Heidelberg Multi ... Oculus delivers a microprocessor-controlled ... vision in the red/green ... blue/green range (Moreland equation) ...
Medicine Products: