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Genzyme Delivers Strong Fourth Quarter to Conclude Outstanding Year
Date:2/13/2008

$(0.123) $(0.116) $0.30

Diluted (1) $(0.115) $(0.108) $0.29

Weighted average shares

outstanding:

Basic 265,418

Diluted (1) 283,374

(1) GAAP As-Reported diluted earnings per share and diluted weighted

average shares outstanding reflect the adoption of EITF 04-8. In

accordance with the provisions of EITF 04-8, interest and debt fees

related to our 1.25% convertible senior notes of $1,884K, net of tax,

have been added back to net income and approximately 9,686K shares

have been added to diluted weighted average shares for purposes of

computing GAAP As-Reported diluted earnings per share.

GENZYME 2008 GUIDANCE

2008 Guidance

DESCRIPTION Ranges

Renagel / Renvela $690 $700

Total Renal 800 815

Cerezyme 1,215 1,240

Fabrazyme 495 505

Myozyme 320 330

Aldurazyme 135 145

Total Therapeutics 2,325 2,385

Total Transplant 210 220

Synvisc 270 280

Total Biosurgery 490 505

Total Diag/Genetics 475 485

Total Other 260
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SOURCE Genzyme Corporation
Copyright©2008 PR Newswire.
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