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Genstruct and Gene Logic Collaborate on Systems Toxicology
Date:2/25/2009

SAN FRANCISCO, CAMBRIDGE, Mass. and GAITHERSBURG, Md., Feb. 25 /PRNewswire/ -- (CHI's Molecular Medicine Tri-Conference) - Genstruct Inc., a systems biology company focused on identifying molecular mechanisms, networks and biomarkers to better develop novel therapeutics, molecular diagnostics and patient-specific therapies, today announced that it has signed a partnership agreement with Gene Logic, an Ocimum Biosolutions company, for a systems toxicology collaboration.

As part of this collaboration, Gene Logic will provide its extensive toxicology databases and data on specific compounds obtained by the company's gene expression technology for preclinical and clinical research to clients from the pharmaceutical, biotechnology, consumer products and related industries. With its state-of-the-art methodology and expertise in toxicity mechanisms, Genstruct will apply its Causal Network Modeling(TM) platform for systems biology to create network models that fully capture the toxicity potential of any compound.

"We are excited by the potential of combining the skill sets of the two companies," said Dr. Keith O. Elliston, president and CEO at Genstruct. "In Genstruct's work with pharmaceutical clients, we have characterized complex and poorly understood mechanisms of toxicity such as idiosyncratic drug-induced liver injury and hemangiosarcoma. We can now evaluate a new compound's potential to elicit these types of reactions in man based on data from simple animal studies. Partnering with a highly regarded data provider like Gene Logic, we can now offer pharmaceutical clients of both companies tremendous additional value in toxicity evaluation."

"This partnership with Genstruct, a very reputed player in the systems biology space is a natural connect with Gene Logic as Keith Elliston was the CSO of Gene Logic in the early days," said Ms. Anuradha Acharya, CEO, Gene Logic. "As the global pharma landscape is changi
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SOURCE Genstruct Inc.
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