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Genomic profiling of lung tumors helps doctors choose most effective treatment
Date:9/28/2007

form of cancer.

Standard therapy often includes administration of what is called platinum-based chemotherapy, which works by damaging DNA and interrupting the chain of cellular events that leads to cancer proliferation. Response rate to this type of chemotherapy, however, is about 20 to 30 percent, meaning that up to 80 percent of patients getting this treatment do not see their tumors shrink in response to therapy. Those patients may go on to receive what is known as second-line therapy: drugs such as pemetrexed or docetaxel, which work by interrupting the cellular machinery of tumor cells.


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Contact: Lauren Shaftel Williams
lauren.shaftel@duke.edu
919-684-4966
Duke University Medical Center
Source:Eurekalert

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