Navigation Links
Genome sequencing used to assess a novel form of Clostridium botulinum
Date:3/7/2011

C on our doorstep was extremely useful for this project, and will be a boon for IFR science," said Professor Peck. "It has enabled us to evaluate the threat that this new strain may pose to food safety and biosecurity by rapidly delivering a complete genome, finished genome sequence."

IFR and TGAC are institutes of the Biotechnology and Biological Sciences Research Council (BBSRC), which funded this research.

The genome was annotated at TGAC by Dr Lisa Crossman. Annotating the genome involves looking at the genomic sequence, and working out where the genes themselves are, and what they may do. This is done by comparison with genes of known function from other bacteria.

"We first annotated the genome automatically, but because of the importance in obtaining a high quality set of genes, we manually curated the most interesting parts of the genome," said Dr Crossman.

The 3.9 Mb genome is structurally similar to other strains of C. botulinum. The scientists identified the gene that produces the neurotoxin, which is in the same location as in many other C. botulinum strains, and confirmed that no other neurotoxin genes were present. The genes needed for spore germination are similar to those in related strains.


'/>"/>

Contact: Andrew Chapple
andrew.chapple@bbsrc.ac.uk
44-016-032-51490
Norwich BioScience Institutes
Source:Eurekalert

Page: 1 2

Related medicine news :

1. WSU study may lead to greater understanding of human genome regulation
2. IDIBELL researchers discover a substance against the dark genome of cancer
3. Whole genome sequencing used to help inform cancer therapy
4. First Look at Prostate Cancer Genome Yields Insights
5. Orangutan Genomes Reveal Some Surprises
6. Punctuated evolution in cancer genomes
7. Genome code cracked for most common form of pediatric brain cancer
8. Targeted therapy reactivates guardian of the genome in resistant cancer
9. Wistar researchers discover new class of objects encoded within the genome
10. Genome Studies Point to Cholesterol-Regulating Genes
11. Of lice and man: Researchers sequence human body louse genome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... December 26, 2014 The ... combines beauty, strength and durability. Today, the business ... which is valid until Jan. 30, 2015. , ... of traditional hardwood. BambooFlooringChina.com is a well-known brand ... consumers worldwide to find a reliable bamboo flooring ...
(Date:12/25/2014)... Recently, iFitDress.com, the popular online supplier of wedding dresses ... selection of black one-shoulder cocktail dresses . In addition, ... available at discounted prices, up to 70% off. ... three weeks only. You know, we have thousands of frequent ... our new items can visit our website for more details. ...
(Date:12/25/2014)... 2014 Helen Harris’ RP (Retinitis Pigmentosa) ... California after an 8 year battle with breast cancer. ... evening in her home in Woodland Hills California after ... , As the founder and volunteer ... pioneered and championed many of today's greatest breakthroughs in ...
(Date:12/25/2014)... News) -- Overeating is common during the holidays, but there ... expert says. "Don,t arrive at a party hungry. It ... you,ll be attending a party, but deprivation leads to hunger, ... Northern Westchester Hospital in Mount Kisco, N.Y., said in a ... the day and even to have a snack before attending ...
(Date:12/25/2014)... ” was featured on NewsWatch as part of its monthly ... the iOS, Android, and Windows markets. Andrew Tropeano, a mobile ... and shared with viewers how this is an application for ... “A picture says a thousand words.” It’s true. There are ... because each picture holds a unique and special meaning. Photos ...
Breaking Medicine News(10 mins):Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4Health News:An Application to Create Custom Stickers was Featured on NewsWatch Television on December 19, 2014 2
... from Shropshire and parts of Wales. Breast cancer patients from ... but Welsh women get it for free. // ,This ... to pay for Herceptin for early stage breast cancer sufferers ... the welsh as all Welsh Local Health Boards have agreed ...
... in the capital of Zagreb it was revealed that a dead ... flu virus. //, ,The location of the dead swan was ... weekend. Tests confirmed that the dead bird had contracted the H5 ... it was the lethal H5N1 strain would be released on Sunday ...
... simulated investment game, a study, intending to investigate ... working //collectively in a team, revealed stark observations ... conducted by the University of Erfurt team, found ... when ‘punishments’ became a form of motivation. Psychologists ...
... nations should be prepared to pledge more money to combat ... ,Western and Asian donors had pledged $1.9 billion ... flu and improve containment and prevention methods in 12 countries, ... spreading across the world through migratory birds, including infections in ...
... should avoid exposure to the fumes of solvents used ... and lacquers//, could give rise to allergies in young ... Germany's environmental agency. ,Pregnant women should leave ... stay clear of the work area altogether. ...
... has warned the nation's betel-nut chewers of the increased ... habits like smoking and drinking. ,According to ... National Health Research Institute when betel nut chewing was ... cancer of the esophagus was about 195 times higher ...
Cached Medicine News:Health News:Free Herceptin Treatment for Those Who Live Over the Welsh Border 2Health News:Motivation Yardstick: Rewards or Punishment? Discover the Superior Performance Trigger 2Health News:Cancer Risks for Betel Nut Chewers 2
(Date:12/22/2014)... , Dec. 22, 2014  CytoSorbents Corporation ... its CytoSorb® blood purification technology to help fight ... in 28 countries worldwide, today announced the appointment ... MD, FACS, as its Senior Vice President of ... Dr. Di Russo is an ...
(Date:12/22/2014)... , Dec. 22, 2014 Research and Markets ... of the "US Self-monitoring Blood Glucose Market" ... http://photos.prnewswire.com/prnh/20130307/600769 This market insight focuses on ... the United States . Reimbursement analysis ... Thorough product analyses for more than 73 SMBG meters ...
(Date:12/22/2014)... 22, 2014  ConvaTec, a privately-held medical products and ... appointed Interim Chief Executive Officer of the company, effective ... Ken Berger .  "The Board of Directors of ConvaTec ... over the past three years," said Magnus Lundberg ... are confident that the company is well positioned for ...
Breaking Medicine Technology:CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5US Self-monitoring Blood Glucose Market 2ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2
... ArtJen Complexus Holdings,Corp. (http://www.fbcx.com ) today announced ... type 2 diabetics and an animal study at the,National ... major US,west-coast university medical center. The largest study to ... dietary fat will involve,overweight but not obese individuals. ...
... PLAINS, N.Y., Sept. 18 Millennium Pharmaceuticals,and ... interim analysis of a large,randomized, international Phase ... combination with Velcade(R) (bortezomib) showed that the,patients ... These patients, who are not,eligible for a ...
Cached Medicine Technology:ArtJen Announces Major Clinical Trial of Its Patented Weight Loss Product FBCx 2The Leukemia & Lymphoma Society is Encouraged by Promising News for Myeloma Patients 2
... Pipette is a synonym for pipetting accuracy, ... design, and superior operating comfort. Its single, ... measuring stroke and blow-out as well as ... ensures utmost accuracy and precision. Ejection sleeve ...
... is ideal for repeated pipetting ... volume FInnpipettes offer the same ... Finnpipette Digital pipettes: New, ... Soft-touch tip ejection, Safety label, ...
Inquire...
... A fixed pipette is ... a single volume. Fixed volume ... and advantages as other Finnpipette ... design, Super blow-out (1-40ul), Soft-touch ...
Medicine Products: