Navigation Links
Genome of Cancer-Free Rodent May Give Clues to Human Aging, Disease
Date:10/12/2011

By Amanda Gardner
HealthDay Reporter

WEDNESDAY, Oct. 12 (HealthDay News) -- Scientists announced Wednesday that they have succeeded in sequencing the full genome of the naked mole rat, an exceptionally long-lived and cancer-resistant rodent.

While that might not sound like headline news, scientists say the findings could provide insights into human aging and risks for malignancy.

"If we can understand the genetic adaptations, we may be able to find treatments which can change the human into a more long-lived species," said Vadim N. Gladyshev, senior author of the study published online Oct. 12 in the journal Nature.

Another expert, Dr. Greg Enders, associate professor of medicine at Fox Chase Cancer Center in Philadelphia, expressed enthusiasm. "This paper is an interesting piece of work [and may provide] useful hypotheses into how they can have such longevity and not cancer."

However, these ideas are still "all hypothetical in the future and very controversial," added Gladyshev, director of the Center for Redox Medicine at Brigham and Women's Hospital and Harvard Medical School in Boston.

On average, the naked (meaning hairless) mole rat lives more than 30 years, or almost 10 times as long as a typical mouse. Not only are they healthier for a longer period of time than other rodents, they live underground in the dark, are cold-blooded and can reproduce until they die. They do have poor vision, however.

"They have many unusual traits, and all of them are important in some way," said Gladyshev. "They are long-lived, live in low-oxygen conditions, are resistant to cancer, [and] don't maintain a stable body temperature."

In analyzing the genome of this remarkable mammal, the researchers noted some similarities with other mammals. The number of genes is about the same in naked mole rats (22,561), humans (22,389), mice (23,317) and rats (22,841).

Many of the naked mole ra
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. GenomeQuest Hosts Seminar Focused On Web-based Searching for Patent Information Across Global Sequence Databases
3. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
4. Mayo oral cancer study shows full tumor genome
5. Entire Family Genome Sequenced for First Time
6. Medicines Future Could Lie in Each Patients Genome
7. Human Genome Turns 10
8. Genome Sequencing Reveals How Breast Cancer Spreads
9. Patients whole genome reveals risk of diseases and adverse drug responses
10. Genome Scan Gives Man Insight Into Future Health Risks
11. Genome breakthrough allows scientists to identify and profile tumor cells from very small samples
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genome of Cancer-Free Rodent  May Give Clues to Human Aging, Disease
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... the University of Illinois at Chicago are taking part ... 2,000 autism patients and their families over the next ... Collection, is the first coordinated effort to create a ... child. , "This collection of DNA will allow researchers ...
... since last year mean seniors should shop wisely, experts ... the enrollment period for Medicare,s Part D prescription drug ... are advising seniors to choose a plan carefully because ... plan. , "As we enter the fourth year of ...
... published by The Feinstein Institute for Medical ... and disease pathogenesis at the molecular level ... use that knowledge in the design of ... prognosis, and prevention. Featured in the ...
... software free of charge to customers purchasing its market leading ... ... Fort Collins, CO (PRWEB) November 14, 2008 -- Privacy ... Email Integrity Program for customers purchasing Privacy Networks, market leading ...
... diagnostic measures, British researchers report , , THURSDAY, Nov. 13 ... standard test for measuring the activity of the heart ... problems for people who are examined because of chest ... stable chest pain, suspected angina, the resting EKG was ...
... Nov. 13 The U.S. government,through the U.S. ... five planned shipments of U.S. emergency assistance to ... In coordination with the,UN Children,s Fund (UNICEF), approximately ... 5,400 water containers, 500,rolls of plastic sheeting, and ...
Cached Medicine News:Health News:UIC joins international research effort to study autism 2Health News:Enrollment for Medicare Drug Plans Begins Again 2Health News:Enrollment for Medicare Drug Plans Begins Again 3Health News:Researchers Tackle CLL, Diabetes and Trauma-Hemorrhage, 2Health News:Message Archiving Leader Privacy Networks Announces Free Anti-Spam Software to Businesses and Organizations 2Health News:Message Archiving Leader Privacy Networks Announces Free Anti-Spam Software to Businesses and Organizations 3Health News:EKG Not Strong Predictor of Heart Risk 2Health News:EKG Not Strong Predictor of Heart Risk 3Health News:First U.S. Flight with Humanitarian Goods Arrives in Democratic Republic of Congo 2
(Date:12/22/2014)... HOUSTON , Dec. 22, 2014 Cyberonics, Inc. ... devices for the treatment and management of epilepsy, today announced ... Morgan Healthcare Conference on Wednesday, January 14, 2015, in ... , Cyberonics, President and Chief Executive Officer, will speak at ... presentation can be accessed by clicking on the Investor Relations ...
(Date:12/22/2014)... Dec. 22, 2014 /PRNewswire/ -- RXi Pharmaceuticals Corporation (NASDAQ: ... on discovering, developing and commercializing innovative therapies addressing ... issued the following open letter to shareholders from ... Med. Sc. Dear RXi Shareholders, ... of inaccurate statements posted on certain social media ...
(Date:12/22/2014)... ALTO, Calif. , Dec, 22, 2014 /PRNewswire/ ... a Phase 2a study of lonafarnib in patients ... study was conducted at the National Institutes of ... Maryland .  The double-blinded, randomized, placebo-controlled, dose ... mg twice daily and 200 mg twice daily ...
Breaking Medicine Technology:RXi Pharmaceuticals Issues Open Letter to Shareholders 2RXi Pharmaceuticals Issues Open Letter to Shareholders 3RXi Pharmaceuticals Issues Open Letter to Shareholders 4RXi Pharmaceuticals Issues Open Letter to Shareholders 5RXi Pharmaceuticals Issues Open Letter to Shareholders 6Eiger Bio Announces Positive Data in Patients Infected with Hepatitis Delta Virus (HDV) Treated with Lonafarnib - Results Presented at American Association for the Study of Liver Diseases (AASLD) Meeting 2Eiger Bio Announces Positive Data in Patients Infected with Hepatitis Delta Virus (HDV) Treated with Lonafarnib - Results Presented at American Association for the Study of Liver Diseases (AASLD) Meeting 3
REFRESH TEARS® lubricating eye drops does more than just smoothe and relieve dry, irritated eyes. REFRESH TEARS® creates a shield of protection against further irritation with its unique, lon...
... REFRESH ENDURA™ is the ... to benefit all 3 layers ... coating of moisture that lubricates ... your eyes). This helps seal ...
ALPHAGAN® (brimonidine tartrate ophthalmic solution) 0.2% is indicated for lowering IOP in patients with open-angle galucoma or ocular hypertension....
... solution is a prescription eye drop ... to use after your cataract surgery. ... may cause them to become inflamed. ... inflammation include redness and swelling. If ...
Medicine Products: