Navigation Links
Genome Scans May Reveal Life-Saving Alternatives for Cancer Patients
Date:4/19/2011

By Amanda Gardner
HealthDay Reporter

TUESDAY, April 19 (HealthDay News) -- A 39-year-old woman is referred to Washington University's Siteman Cancer Center in St. Louis with suspected acute myeloid leukemia (AML), a cancer that can be treated relatively simply with medication, or not so simply with a high-risk stem cell transplant, depending on the tumor subtype.

But finding out which type of cancer she has proves trickier than expected.

While the pathologist sees a type of leukemia known as M3AML, which generally has a good outcome and can be treated with the drug ATRA, the cytogeneticist sees something entirely different. In his analysis, the woman has a type of leukemia with poor long-term survival that is usually treated with stem cell transplantation -- a risky therapy that sometimes leads to death.

Fortunately, in this case study, documented in the April 20 issue of the Journal of the American Medical Association, the woman's oncologist is aware of a clinical trial and, deferring treatment for six weeks, refers her there so the researchers can do a full scan of her genome -- and come up with an answer.

Full-genome sequencing involves scanning all the thousand of genes on the human genome to try to find a mistake. It's different from the more common gene testing these days, which looks only for specific DNA that might or might not be responsible for a particular problem.

In the St. Louis case, the more in-depth sequencing, done in only seven weeks, uncovered a new genetic "mistake" that showed the woman could be treated with ATRA and not the more-complicated, risky stem cell transplantation.

"A small portion of chromosome 15 had popped into chromosome 17," explained Richard K. Wilson, co-author of two case studies on full-genome sequencing in the journal.

The woman in this case study is now in remission and researchers have actually used the new information to as
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Mouse cancer genome unveils genetic errors in human cancers
2. Genome sequencing used to assess a novel form of Clostridium botulinum
3. WSU study may lead to greater understanding of human genome regulation
4. IDIBELL researchers discover a substance against the dark genome of cancer
5. Whole genome sequencing used to help inform cancer therapy
6. First Look at Prostate Cancer Genome Yields Insights
7. Orangutan Genomes Reveal Some Surprises
8. Punctuated evolution in cancer genomes
9. Genome code cracked for most common form of pediatric brain cancer
10. Targeted therapy reactivates guardian of the genome in resistant cancer
11. Wistar researchers discover new class of objects encoded within the genome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... August 20, 2014 The ... (IBCCES) , an organization recognizing professionals dedicated to ... has announced that with a certificate in ... people on the Autism Spectrum have a way ... quality care. This, in turn, say IBCCES representatives, ...
(Date:8/20/2014)... 2014 Today, Zane Benefits, the ... of a new eBook, Affordable Care Act 101. ... owners feel uncertain about how the ACA impacts ... bottom line. , The new eBook outlines key ... navigate their upcoming health insurance decisions. , Read ...
(Date:8/20/2014)... August 20, 2014 A new trend ... a medical exam before issuing an approximate quote for ... company is now helping the public to obtain life ... system at http://quotespros.com/life-insurance.html . , The coverage ... more regulations have appeared in many U.S. states. Some ...
(Date:8/20/2014)... FL (PRWEB) August 20, 2014 Locating rates ... users of the Quotes Pros website. A new source of ... price and review rates good for all 50 states at ... configured is one of the new methods available for the ... insurer packages that are supplied. The instant quotations that are ...
(Date:8/20/2014)... New York, NY (PRWEB) August 20, 2014 ... Open Tennis Championship tickets in NYC. In just a ... USTA Billie Jean King Tennis Center. The event was originally founded ... the 2013 event, Rafael Nadal was forced to withdrawal from the ... of the 2014 women’s tournament and will return to New York ...
Breaking Medicine News(10 mins):Health News:National Autism Certificate Credentialing Board IBCCES Increases Job Placement Opportunities for Those Dedicated to Working Within the Autism Spectrum 2Health News:National Autism Certificate Credentialing Board IBCCES Increases Job Placement Opportunities for Those Dedicated to Working Within the Autism Spectrum 3Health News:Life Insurance Quotes Without Medical Exams Now Displayed to Adults at Insurance Website 2Health News:Term Life Insurance Price Database Now Helps Quote Prices for Adults in 50 States Online 2Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 2Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 3Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 4Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 5
... , , NORTHBROOK, Ill., ... drinking water quality and safety, announced today a new certification ... demonstrate compliance with new, stricter low lead requirements that will ... , California Assembly Bill 1953 (AB 1953), now a state ...
... , , RIO DE JANEIRO, Dec. 21 Amilpar (Bovespa: ... largest managed care organization in Brazil, in accordance with article ... CVM Instruction nº 358/02, and in addition to the Relevant ... 9, 2009, informs its shareholders and the market that its ...
... A ... find out who has the most compelling dental story. The winner will be determined by an ... ... Austin, Texas cosmetic dentistry practice, is getting ready to let the world know who ...
... ... lift spirits. , ... 21, 2009 -- The Peachtree Evolution Series LED wall sconce takes the art of multi-colored ... design of any space. , , ,Choose a Vibrant and fast moving sequence for clubs, ...
... 20 More than 40 groups have joined together to ... "Virtual Vigil" starting at 9 pm tonight and wrapping after ... representing millions on the left, right, seniors, tea parties, doctors, ... Senate for laying a $200 billion windfall in mandatory premiums ...
... expert says , SUNDAY, Dec. 20 (HealthDay News) -- Think twice ... your holiday wish list. You may get it and find out ... you thought you would, a new study suggests. , That,s because ... to our expectations. The cappuccino machine is a hassle to clean, ...
Cached Medicine News:Health News:Underwriters Laboratories Announces Alternative Certification Program for Lead Free Verification of Cooking and Plumbing Products 2Health News:10 Days Left to Win $15,000 in Dental Work for Most Interesting Patient in the World Contest at Austin Cosmetic Dentistry Practice 2Health News:Add Drama and Lift Spirits While Significantly Reducing Energy Cost; Peachtree Introduces the Evolution Series, LED, Energy Efficient Wall Sconce 2Health News:Left/Right Healthcare 'Virtual Vigil' Tonight at 9 PM Until Senate Votes; Broad Coalition Says Punishes Some States, Windfall for Insurance Companies 2Health News:Be Careful What You Wish For This Holiday Season 2
(Date:8/20/2014)... , Aug. 20, 2014  The National Association ... latest results achieved by the real-time, pseudoephedrine (PSE) ... National Precursor Log Exchange (NPLEx), automatically blocks unlawful ... down meth offenders and make arrests. Data released ... Indiana blocked the sale of more ...
(Date:8/20/2014)... 20, 2014  The National Association of Drug ... achieved by the real-time, pseudoephedrine (PSE) blocking system ... Log Exchange (NPLEx), automatically blocks unlawful PSE sales ... offenders and make arrests. Data released by NPLEx ... blocked the sale of more than 23,478 ...
(Date:8/20/2014)... Aug. 20, 2014 The National Association ... latest results achieved by the real-time, pseudoephedrine (PSE) ... National Precursor Log Exchange (NPLEx), automatically blocks unlawful ... down meth offenders and make arrests. Data released ... Kansas blocked the sale of more ...
Breaking Medicine Technology:Indiana's Stop-Sale System Achieves Significant Results In Battle Against Meth 2Kentucky's Stop-Sale System Achieves Significant Results In Battle Against Meth 2Kansas's Stop-Sale System Achieves Significant Results In Battle Against Meth 2
... Ltd. (Sun) (Reuters: SUN.BO, Bloomberg: SUNP IN, NSE: SUNPHARMA, ... Israel has unanimously dismissed the appeal by Taro Pharmaceutical ... of the previous ruling by the Tel-Aviv District Court ... do not apply to the Tender Offer by Sun,s ...
... Havel,s Incorporated, the Cincinnati-based market leader in echogenic ... echogenic ultrasound needle which could help reduce radiation ... echogenic needles using their new, innovative Micro Laser ... to reflect sound waves back to the transducer ...
Cached Medicine Technology:Supreme Court of Israel Rules in Favor of Sun Pharma 2Supreme Court of Israel Rules in Favor of Sun Pharma 3Havel's Incorporated Helping to Reduce Radiation Exposure with New EchoTuohy™ Ultrasound Needle 2
... the world's first directly illuminated, hand-held ... tradition of bringing superior ophthalmic technology ... keeping with that tradition, Welch Allyn ... Ophthalmoscope. With its newly designed precision ...
... The TOPCON 3D+ ALE-3700/3700PC/3700CF patternless processing system ... frame, quickly, accurately and with the convenience ... the 3D+ FR-20 Frame Reader, advanced processing ... is available with a polycarbonate feature (ALE-3700 ...
Inquire...
... Model II, is very simple to use ... obtained because it is only necessary to ... with internal reading scales then indicating the ... Since displacements between the centers of spectacle ...
Medicine Products: