Navigation Links
Genome Mapped for Type 2 Diabetes
Date:2/5/2010

Finding may further understanding of common diseases, researchers say

FRIDAY, Feb. 5 (HealthDay News) -- Scientists have completed a map of areas of the human genome that control which genes are switched on or off in type 2 diabetes, a finding that may advance understanding of the genetic basis of this and other common diseases.

"Most of the human genome is uncharted territory -- entire stretches of sequence with no clear function or purpose," study co-senior author Jason Lieb, an associate professor of biology at the University of North Carolina at Chapel Hill, said in a news release.

"In fact, the majority of the DNA sequences associated with disease found thus far reside in the middle of nowhere. Here we have developed a map that can guide scientists to regions of the genome that do appear to be functionally relevant, instead of a dead end."

Using a new method (called FAIRE-seq) developed in Lieb's laboratory, the researchers produced the first high-resolution atlas of these regulatory elements in pancreatic islet cells, the most studied cell type for the treatment and prevention of type 2 diabetes.

The study was published online recently in Nature Genetics.

This map is likely to help identify new genetic targets for understanding and treating type 2 diabetes, but the method used in this study isn't limited to diabetes or pancreatic islet cells. Lieb plans to use FAIRE-seq to investigate other cells, including immune cells.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about diabetes.



-- Robert Preidt



SOURCE: University of North Carolina at Chapel Hill School of Medicine, news release, Feb. 2, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. One Species Genome Found Within Another
2. Genome Area Linked to Rheumatoid Arthritis
3. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
4. Scientists Map Elephantiasis Parasites Genome
5. Scientists Map Intestinal Bugs Genome
6. Hopkins researchers release genome data on autism
7. Baylor College of Medicine increases fleet of Roche Genome Sequencer FLX Systems to 10 instruments
8. Cats Genome Map Purrfected
9. Domestic cat genome sequenced
10. Guardian of genome predicts treatment outcomes for childhood cancer
11. Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... ... May 02, 2016 , ... MedPro Waste Disposal, LLC ... service. MedPro now offers its mail back service for an all-inclusive rate. MedPro ... now able to provide service to all of the clients in the country who ...
(Date:5/2/2016)... Veendam, The Netherlands (PRWEB) , ... May 02, 2016 , ... ... Products is honored to announce that the new WHIMZEES Variety Value Boxes were selected ... EXPO 2016 New Product Showcase Award. , WHIMZEES natural dental chews for dogs ...
(Date:5/2/2016)... ... 02, 2016 , ... Dr. Rassouli, dentist in Orange County, CA ... the research, which was published in the “Journal of the American Geriatrics Society,” more ... million Americans have Alzheimer’s disease. The study found that dental problems may increase the ...
(Date:5/2/2016)... ... ... 2016 World Ultimate & Guts Championship (WUGC) Mixed roster was announced in February and Chris ... is being held in London, England this year from June 18-25. At the last WUGC ... in the women’s masters division, and a silver in the women’s division, so Mazur hopes ...
(Date:5/2/2016)... ... , ... According to an American Psychological Association article, the Centers ... the age of 18. Of those who survive, many still face effects as they ... In her new book, Lyah! Lyah! Pants on Fyah!, she shares stories from women ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , Net Sales of $1.90 billion represent an increase of ... and an increase of 1.2% on an adjusted pro forma, ... quarter were $0.52 reported, a decrease of 47.5% from the ... over the prior year period , The Company increases ... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) today ...
(Date:4/28/2016)... 28, 2016 TapImmune,Inc. (TPIV), ... peptide and gene-based immunotherapeutics and vaccines for the treatment of ... at the 3rd Annual Growth Capital Expo to ... 2016 at Caesars Palace in Las Vegas, Nevada.  The ... May 4 th by Dr. John N. Bonfiglio ...
(Date:4/27/2016)... 2016   , ... Recurring Consumable Sales  Clinical sales grow 16% ... (Euronext: MKEA, OTCQX: MKEAY) inventor of Cellvizio®, the multidisciplinary ... the first quarter ended March 31, 2016 and provided ... its commercial strategy. First Quarter 2016 Revenue ...
Breaking Medicine Technology: