Navigation Links
Genome Mapped for Type 2 Diabetes
Date:2/5/2010

Finding may further understanding of common diseases, researchers say

FRIDAY, Feb. 5 (HealthDay News) -- Scientists have completed a map of areas of the human genome that control which genes are switched on or off in type 2 diabetes, a finding that may advance understanding of the genetic basis of this and other common diseases.

"Most of the human genome is uncharted territory -- entire stretches of sequence with no clear function or purpose," study co-senior author Jason Lieb, an associate professor of biology at the University of North Carolina at Chapel Hill, said in a news release.

"In fact, the majority of the DNA sequences associated with disease found thus far reside in the middle of nowhere. Here we have developed a map that can guide scientists to regions of the genome that do appear to be functionally relevant, instead of a dead end."

Using a new method (called FAIRE-seq) developed in Lieb's laboratory, the researchers produced the first high-resolution atlas of these regulatory elements in pancreatic islet cells, the most studied cell type for the treatment and prevention of type 2 diabetes.

The study was published online recently in Nature Genetics.

This map is likely to help identify new genetic targets for understanding and treating type 2 diabetes, but the method used in this study isn't limited to diabetes or pancreatic islet cells. Lieb plans to use FAIRE-seq to investigate other cells, including immune cells.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about diabetes.



-- Robert Preidt



SOURCE: University of North Carolina at Chapel Hill School of Medicine, news release, Feb. 2, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. One Species Genome Found Within Another
2. Genome Area Linked to Rheumatoid Arthritis
3. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
4. Scientists Map Elephantiasis Parasites Genome
5. Scientists Map Intestinal Bugs Genome
6. Hopkins researchers release genome data on autism
7. Baylor College of Medicine increases fleet of Roche Genome Sequencer FLX Systems to 10 instruments
8. Cats Genome Map Purrfected
9. Domestic cat genome sequenced
10. Guardian of genome predicts treatment outcomes for childhood cancer
11. Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... New Jersey (PRWEB) , ... March 23, 2017 ... ... developer of herbal-based and non-steroidal skincare products, was awarded as winners of American ... innovation products. This competition was hosted jointly by HSN and Good Housekeeping. , ...
(Date:3/23/2017)... ... 23, 2017 , ... The Boulevard is honored to host Shriners and Masons ... be located in the Main West Entrance of The Boulevard (in front of JCPenney). ... is necessary and each child with a parent or guardian will be photographed for ...
(Date:3/23/2017)... ... ... “Beyond and Back”: a true-life testimony of tragedy and the miraculous power ... Rose, a wife, mother and grandmother committed to sharing her many spiritual adventures which ... new book presents actual events in the life of her family, which validate her ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... ... has selected HealthiPASS, an innovative patient - centric payment system, to expand its ... massive improvements in the patient financial experience. , “At Ogden Clinic, we ...
(Date:3/23/2017)... ... March 23, 2017 , ... “More Corruption”: a simple and strong explanation of the God’s ... the rulers of Heaven was asked by God to write a book about Him. , ... just because I kept my commitment to the Lord God. They have not walked in ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... , Mar 23, 2017 NeuroVive Pharmaceutical ... today announced that the English version of the Annual report ... www.neurovive.com .  ... About NeuroVive NeuroVive Pharmaceutical AB is a ... discovery and development of medicines that preserve mitochondrial integrity and ...
(Date:3/22/2017)... -- Research and Markets has announced the addition of ... Industry Forecast to 2025" report to their offering. ... The Global Respiratory care ... 10.9% over the next decade to reach approximately $38.27 billion by ... and forecasts for all the given segments on global as well ...
(Date:3/22/2017)... Under the impetus of the fast-growing ... increased year by year at the CAGR of ... market size will maintain the growth rate of ... billion in 2021, thanks to severe aging, the ... agents and supporting policies. At present, Chinese ...
Breaking Medicine Technology: