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Genetics May Determine Antidepressants' Effectiveness
Date:1/23/2008

reatment of brain diseases are genotyped to exclude the possibility that a patient receives a drug that fails to enter the CNS to an extent required for efficacy," the study authors wrote.

Future development of antidepressants should take into account whether new drugs are transported by P-gp, and clinical trials of antidepressant drugs need to factor in the P-gp genetic status of participants, the researchers recommended.

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The U.S. National Institute of Mental Health has more about depression.



-- Robert Preidt



SOURCE: Cell Press, news release, Jan. 23, 2008


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Genetics May Determine Antidepressants' Effectiveness
Genetics May Determine Antidepressants' Effectiveness
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