Navigation Links
Genetic variations associated with susceptibility to bacteria linked to stomach disorders
Date:5/7/2013

l implications of the current findings are unknown. Based on these data, genetic testing to evaluate H pylori susceptibility outside of research projects would be premature."

"If confirmed, genetic variations in TLR1 may help explain some of the observed variation in individual risk for H pylori infection," the researchers conclude.

(JAMA. 2013;309(18):1912-1920; Available pre-embargo to the media at http://media.JAMAnetwork.com)

Editor's Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Editorial: Helicobacter pylori Susceptibility in the GWAS Era

In an accompanying editorial, Emad M. El-Omar, M.D., of Aberdeen University, Aberdeen, United Kingdom, writes that the authors of this study are appropriate to state, "based on their data, genetic testing to evaluate H pylori susceptibility is premature."

"This would be superfluous, because nongenetic testing for the infection can be accomplished at a fraction of the cost. There is a bigger picture: understanding genetic susceptibility to H pylori is essential for understanding how to overcome this infection. The current approach to eradication of the infection is limited and based entirely on prescribing a cocktail of antibiotics with an acid inhibitor to symptomatic individuals. However, H pylori antibiotic resistance is increasing steadily, and eventually curing even benign conditions such as peptic ulcer disease arising from H pylori will be difficult. When considering gastric cancer, another H pylori-induced global killer, the necessity for understanding the pathogenesis of the infection and the role of host genetics in susceptibility is even greater. The corollary is that better understanding of infections, i
'/>"/>

Contact: Markus M. Lerch
lerch@uni-greifswald.de
The JAMA Network Journals
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Research Suggests that Lack of Exercise Drive is Genetic, Making Energy Enhancing Supplements Like Prescopodene Beneficial For Sticking to Your Exercise Routine
2. Scientists revolutionize the creation of genetically altered mice to model human disease
3. New genetic clues to breast and ovarian cancer
4. International study finds new genetic links to juvenile arthritis
5. More accurate, powerful genetic analysis tool opens new gene-regulation realms
6. Genetic markers linked to the development of lymphedema in breast cancer survivors
7. Genetic variation contributes to pulmonary fibrosis risk
8. Johns Hopkins experts to present genetics advances at international meeting this weekend
9. Effect of medication is affected by copies of genetic information
10. Liver transplantation for patients with genetic liver conditions has high survival rate
11. Mosquito genetic complexity may take a bite out of efforts to control malaria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying women’s ... discounted prom dresses, most of which are priced under ... company, the promotion is valid until Jan. 22, 2015; ... UK market. , The prom dresses in this new ... A-line strapless, empire strapless chiffon, one shoulder, floor-length, V-neck ...
(Date:12/25/2014)... California (PRWEB) December 25, 2014 Helen ... home in Woodland Hills, California after an 8 year ... away on Christmas Eve evening in her home in ... aggressive metastatic breast cancer. , As ... over forty years, she pioneered and championed many of ...
(Date:12/25/2014)... THURSDAY, Dec. 25, 2014 (HealthDay News) -- The risk ... the holidays, so you need to be extra cautious, ... Day, we see a significant increase in patients coming ... at the Suffolk County Volunteer Firefighters Burn Center of ... celebrations should be full of joy, but if not ...
(Date:12/25/2014)... AngelWeddingDress.com tries its best to translate ... Today, the business has introduced its new collection of ... promotion. , The new prom outfits are guaranteed to ... lover. They are specially designed for 2015. Anyone who ... should visit its website before Jan. 26, 2015, the ...
(Date:12/25/2014)... 2014 Residents at Abernethy ... showed their generous spirit by providing holiday gifts ... Parenting Network- Grandparents Raising Grandchildren program. , Following ... the largest Christmas tree on the campus of ... residents of the Abernethy Village Association (AVA). Each ...
Breaking Medicine News(10 mins):Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4Health News:Don't Let Burns Mar Your Holidays 2Health News:Angelweddingdress 2015 Prom Dresses Online Now 2Health News:Retirement Community Residents Make Impact During Holiday Season 2
... February is Heart ... … while having fun, too. , ... Los Angeles (Vocus) January 25, 2010 -- Every year, over 40,000 American women die ... to be one of them! , , , , ,February is Heart Health Month. Self-care ...
... ... hablan de disparidades e instan a los grupos de socorro a que tengan en ... ... del pasado indica que probablemente las mujeres y los niños en Haití no estén ...
... Center at the University of California, San Diego and ... between county hospitals and private providers. Patients treated in ... patients treated in private facilities tend to receive radiation ... the journal Cancer on January 25. ...
... Children who are mixed-handed, or ambidextrous, are more likely ... childhood than right- or left-handed children, according to a ... . The researchers behind the study, from ... their findings may help teachers and health professionals to ...
... ... the Christian perspective, promote faith-formation. , ... (PRWEB) January 24, 2010 -- Witness to Hope Ministries, a nonprofit ... behavioral health practice in Beaver, PA in order to serve at-risk and special needs ...
... 24, 2010 When University of Utah scientists discovered a ... conducting plastic or polymer, no one could explain how it ... later, the Utah researchers have found these "random lasers" occur ... say such lasers may prove useful for diagnosing cancer. ...
Cached Medicine News:Health News:Save The Ta-Ta's ... And Your Ticker 2Health News:Save The Ta-Ta's ... And Your Ticker 3Health News:Estn las Mujeres y los Nios de Hait Recibiendo Menos Ayuda Tras el Terremoto? 2Health News:Estn las Mujeres y los Nios de Hait Recibiendo Menos Ayuda Tras el Terremoto? 3Health News:Estn las Mujeres y los Nios de Hait Recibiendo Menos Ayuda Tras el Terremoto? 4Health News:Study confirms prostate cancer is treated differently at county vs. private hospitals 2Health News:Mixed-handed children more likely to have mental health, language and scholastic problems 2Health News:Mixed-handed children more likely to have mental health, language and scholastic problems 3Health News:Christian Nonprofit and Behavioral Health Practice Team Up to Help Children 2Health News:How 'random' lasers work 2Health News:How 'random' lasers work 3Health News:How 'random' lasers work 4Health News:How 'random' lasers work 5
(Date:12/24/2014)... LEXINGTON, Mass. , Dec. 23, 2014 /PRNewswire/ ... GEVA ), a biopharmaceutical company developing therapeutic products ... European Medicines Agency (EMA) of the Marketing Authorization ... The EMA recently granted the company,s request for ... the EMA,s regulatory review time.   ...
(Date:12/24/2014)... 2014  Lockton Dunning Benefits, the ... the addition of Vice President Kim Foerster ... Pharmacy Consulting team, Excelsior Solutions. ... to the position.  Most recently, she worked as ... Specialty Pharmacy, where she has held various managerial ...
(Date:12/24/2014)... 23, 2014 Tianyin Pharmaceutical Co., Inc. ... in patented biopharmaceutical, modernized traditional Chinese medicine (mTCM), ... announced that the Company achieved the Public Notice ... (GMP) certificate of TPI,s Qionglai Facility (QLF) from ... public notice period is a significant procedure of ...
Breaking Medicine Technology:Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3Kim Foerster Joins Lockton Companies 2TPI QLF Achieved Public Notice Status of GMP Certification 2TPI QLF Achieved Public Notice Status of GMP Certification 3
... flexible continuous monitoring, the M3 and M4 ... and neonatal patient care. M Series monitors ... includes a basic set of non-invasive parameters ... Optional Multi-Measurement Server extensions offer Mainstream or ...
... On-line Electronic Help (OLEH), an ... to critical anesthesia-related information. OLEH brings ... need it most right on ... care of the patient and ...
Compact networked patient monitors for flexible care....
... for flexible care settings., ,IntelliVue ... portability and measurement flexibility to match ... intermediate care environmentsat the patients side., ... in patient monitoring, IntelliVue has highly ...
Medicine Products: