Navigation Links
Genetic testing may be valuable in treating colorectal cancer
Date:7/27/2009

olorectal cancer. The model assumed that under usual care, patients received a full dose of irinotecan. With genetic testing, irinotecan dosage was reduced 25 percent in individuals identified using the genetic test as having the UGT1A1*28 variant allele. The dose reduction is specified in the Food and Drug Administrationapproved drug label to minimize cases of neutropenia.

Dr. Bruce Schackman, senior author of the study, says, "Cost-effectiveness evaluations of pharmacogenetic tests can provide important insights into both the clinical and economic value of these new treatment paradigms, but few of these types of studies have been conducted. Importantly, these studies also allow us to define in economic terms the value of additional comparative effectiveness research. In this case, we've determined that further research of up to $22 million should be conducted to study the risks and benefits of dose reductions based on the results of the genetic test."

Dr. Schackman is associate professor of public health and chief of the Division of Health Policy in the Department of Public Health at Weill Cornell Medical College.

"This study is an important example of how the combined use of cost-effectiveness analysis and pharmacogenetic testing can improve treatment outcomes," says Dr. Alvin I. Mushlin, Professor and Chairman of the Weill Cornell Department of Public Health. "Both methods are becoming increasingly integral to the advancement of evidence-based medicine."


'/>"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2

Related medicine news :

1. NIH Plan Charts Course to Better Treatments and Cure for Most Common Known Genetic Cause of Autism: Fragile X
2. Studies Show Genetic Activity of Antioxidants
3. Genetic Variation Associated With Survival Advantage in African Americans With HIV
4. Study Shows a Link Between Schizophrenia & Genetic Mutations
5. Teen Behaviors Stem From Genetics, Environment
6. New HHS HRSA Grant Will Fund Development of an Electronic Genetic and Family History Record for Doctors Offices
7. Council for American Medical Innovation Applauds Appointment of Geneticist Francis Collins to Head National Institutes of Health
8. Genetic Breakthrough Spells Hope for Lung Fibrosis Patients
9. Buyer Beware! Know What Youre Getting When You Buy Online Genetic Tests
10. Moles and melanoma -- researchers find genetic links to skin cancer
11. Another Genetic Link to Testicular Cancer Is Found
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015 Joan Lunden, award-winning American journalist, ... the upcoming 32nd Annual Miami Breast Cancer Conference ... Resource®, LLC (PER®) , shares that “a fast-growing, virulent” ... if she had not followed up her clean mammogram ...
(Date:1/22/2015)... Calif. (PRWEB) January 22, 2015 ... Susan Bonilla (D-Concord) and Kristin Olsen (R-Modesto) were ... their leadership in advancing biotechnology, biomedical science, medical ... and Olsen each received the “2014 Life Sciences ...
(Date:1/22/2015)... IsoComforter, Inc. has introduced the most innovative and easy ... treat specific body parts and muscle groups. , IsoComforter, ... use patented cold therapy machine with the innovative IsoTube design ... injuries. IsoComforter has become the industry leader in cold ...
(Date:1/22/2015)... January 22, 2015 Payday lending practices ... communities and cause financial distress to the states that ... at Howard University’s Center on Race and Wealth. , ... economic activity, payday loans at the same time substantially ...
(Date:1/22/2015)... 22, 2015 As interest in the value ... gains momentum worldwide, Rev. Eric J. Hall , president ... (HCCN), will be the keynote speaker on January 27 ... public health system. , The conference, “Hope and Resilience: Innovative ...
Breaking Medicine News(10 mins):Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3
... Implemented to Make Health Care More Accessible ... Members Displaced by Hurricane Gustav, DALLAS, Sept. 2 ... Cross and Blue Shield of,Texas (BCBSTX) announced several actions to ... the impact of Hurricane Gustav was less than,originally anticipated and ...
... suggests , , TUESDAY, Sept. 2 (HealthDay News) -- Suicides among ... 15-year decline, and the trend may owe, in part, to ... Researchers thought a spike in youth suicides in 2004 may ... increase in suicides continued during 2005. , Looking at suicide ...
... of obese adults will develop painful osteoarthritis of the knee ... North Carolina at Chapel Hill suggests. , The study also ... mass index or BMI increased, with the greatest risk found ... were overweight or obese at 45 or older. , "These ...
... A new study shows that the innate immune system ... to airway inflammation, chronic rhinosinusitis and bronchial asthma. Researchers ... have revealed that eosinophils, a particular type of white ... environmental fungus Alternaria alternata . The groundbreaking findings, ...
... on Medicare to Expedite Mandatory Accreditation,Adopt Clearer ... The Power Mobility,Coalition (PMC), an association of ... concerns today about recent findings that,questioned whether ... (CMS),accurately reviewed durable medical equipment (DME) claims ...
... Celebrity Allergy Sufferer Finola Hughes Offers Tips to ... autumn approaches and days cool,down, folks begin preparing ... (Photo: http://www.newscom.com/cgi-bin/prnh/20080902/NETU094 ), For the ... and,asthma, the warmth of home may be anything ...
Cached Medicine News:Health News:Blue Cross and Blue Shield of Texas Prepared to Assist Members Affected by Hurricane Gustav 2Health News:Blue Cross and Blue Shield of Texas Prepared to Assist Members Affected by Hurricane Gustav 3Health News:Youth Suicides Continue to Rise in U.S. 2Health News:Youth Suicides Continue to Rise in U.S. 3Health News:Nearly half of US adults will develop painful knee osteoarthritis by age 85: study 2Health News:Innate immune system targets asthma-linked fungus for destruction 2Health News:Innate immune system targets asthma-linked fungus for destruction 3Health News:Power Mobility Coalition Voices Concern Over Government Reports Outlining Lack of Oversight in the Medicare Durable Medical Equipment Benefit 2Health News:Power Mobility Coalition Voices Concern Over Government Reports Outlining Lack of Oversight in the Medicare Durable Medical Equipment Benefit 3Health News:How To Allergy-Proof Your Home For Fall 2Health News:How To Allergy-Proof Your Home For Fall 3
(Date:1/23/2015)... 23, 2015  Northwest Biotherapeutics, Inc. (NASDAQ: NWBO )("NW ... for operable and inoperable solid tumor cancers, announced today that ... th Annual Phacilitate Immunotherapy Forum in Washington ... will take place on January 26 at 10:30 a.m. EST ...
(Date:1/23/2015)... Jan. 23, 2015 /PRNewswire/-- Harwood Feffer LLP ( www.hfesq.com ) ... of Advaxis, Inc. ("Advaxis" or the "Company") (NASDAQ: ... its fiduciary duties to shareholders. On January ... website reporting that Advaxis had misrepresented the clinical data ...
(Date:1/23/2015)... 23, 2015  iMD Companies, Inc. (ICBU) has repositioned itself as ... and grab a foothold in the hydroponic, hemp and medical ... a presence in the sector, and recently partnering with the ... hemp and medical marijuana, iMD is committing to bring its ...
Breaking Medicine Technology:NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Harwood Feffer LLP Announces Investigation of Advaxis, Inc. 2iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2
... have identified mutations in a gene that predict a high ... Although the researchers caution that further research is needed to ... or IKAROS, lead to leukemia relapse, the findings ... to assess the risk of treatment failure. By using a ...
... Tiantan Puhua Hospital Stem Cells Center ( http://www.stemcellspuhua.com ... to effectively treat neurological disorders, announced today six ... research staff that significantly expand the hospital,s treatment ... The six senior doctors include the distinguished Dr. ...
Cached Medicine Technology:Gene Abnormality Found to Predict Childhood Leukemia Relapse 2Gene Abnormality Found to Predict Childhood Leukemia Relapse 3Gene Abnormality Found to Predict Childhood Leukemia Relapse 4Gene Abnormality Found to Predict Childhood Leukemia Relapse 5Gene Abnormality Found to Predict Childhood Leukemia Relapse 6Stem Cell Treatment Leader Tiantan Puhua Adds Experienced International Medical Staff for Expanding Numbers of Patients 2Stem Cell Treatment Leader Tiantan Puhua Adds Experienced International Medical Staff for Expanding Numbers of Patients 3
... Only Heartlab delivers the performance ... cardiovascular information management systems. As ... and services set the benchmark. ... functionality, high-speed performance and technological ...
The only catheter designed specially for visualization of peripheral vessels: carotids, renals, and illiacs...
... Harmonic Echo technology constructs images ... far less artifacts and noise than ... a technology to transmit distortion-free, fundamental-frequency ... ultrasound beam is a pure sinusoidal ...
AngioSpeed V series, it is an Angiography system designed for vascular treatment in various radiological regions, cardiology, and neurology. SHIMADZU brings you a single system with all units fused t...
Medicine Products: