Navigation Links
Genetic predisposition increases childhood asthma risk
Date:8/20/2007

Children who carry variations in specific genes that metabolize vehicle emissions are more susceptible to developing asthma, particularly if they live near major roadways, a study led by researchers at the University of Southern California (USC) suggests.

Researchers found that children who carried variations in two genes and lived within 75 meters of a major road were up to nine times more likely to develop asthma than children who lived further away, says Muhammad T. Salam, Ph.D. candidate at the Keck School of Medicine of USC, and the studys lead author. The study will appear in the journal Thorax, and is now available online.

This is one of the first studies to report that children with certain genetic backgrounds are even more susceptible to asthma than if they lived near major roads and did not carry the variations, Salam says. We are working to understand how traffic-related exposures may interact with these genes, leading to asthma development.

Asthma is the most common chronic disease in children, and previous studies have shown that traffic-related pollution near the home increases asthma risk and reduces lung growth, according to USC experts.

Researchers drew upon data from the Childrens Health Study (CHS), a longitudinal study of respiratory health among school-age children in 12 Southern California communities. They compared associations between number of genetic variants and exposure to toxins among more than 3,000 study participants.

Researchers found that high levels of microsomal epoxide hydrolase (EPHX1)an enzyme that metabolizes polyaromatic hydrocarbons (PAH) in vehicle emissionswas associated with an increased risk for lifetime asthma. Children with high EPHX1 levels who also carried variations in glutathione S-transferase P1 (GSTP1) genes were four times more likely to have asthma.

Among children who lived within 75 meters of a major road, those with high EPHX1 activity were three times
'/>"/>

Contact: Meghan Lewit
lewit@usc.edu
323-442-2830
University of Southern California
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
2. Crowning glory of 2000!!! Cracking of the genetic code is top of tops
3. Genetic influence in menopause
4. Genetics and cholesterol levels
5. Genetics helps in attacking cancer
6. DNA biochip for genetic screening
7. Genetic disorder related with sleep patterns
8. Genetic innovation
9. Sleepwalking has genetic roots
10. A new genetic label for stroke
11. Genetic tests for cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... maltreatment are 36% more likely to be obese in ... study by King,s College London. The authors estimate that ... child maltreatment could avoid 1 case of adult obesity. ... data from 190,285 individuals from 41 studies worldwide, published ... childhood maltreatment (physical, sexual or emotional abuse or neglect) ...
(Date:5/21/2013)... 21, 2013 The National Resident ... four transitions for its Board of Directors. Hal ... Michigan University School of Medicine, has been named President. ... at the University of California San Diego, is the ... of the Nebraska Medical Center, is the Secretary-Treasurer. ...
(Date:5/21/2013)... It took Willie Benitez, a heroin addict who ... on a fifteen year sentence, six months to convince ... him enough to allow Willie to start up an ... intended to name his “drug rehabilitation foundation,” meaning “no-narcotics” ... start up that class. , Early on, when ...
(Date:5/21/2013)... 21, 2013 Leading New Jersey real ... walkable neighborhoods. One of her favorite aspects of walkable ... health. In light of the current childhood obesity epidemic ... to consider walkable living. , A New York Academy ... spotlights walkable neighborhoods as a key combatant to obesity. ...
(Date:5/21/2013)... Hackensack, NJ (PRWEB) May 21, 2013 ... and Adult) and Director of the Sarcoma Division of ... Center in New Jersey has been named one of ... by Orthopedics This Week. Dr. Wittig is one ... Orthopedic Oncology. The list was created by surveying thought ...
Breaking Medicine News(10 mins):Health News:Child maltreatment increases risk of adult obesity 2Health News:New Board of Directors Leadership for The Match- National Resident Matching Program® 2Health News:New Board of Directors Leadership for The Match- National Resident Matching Program® 3Health News:Narconon Releases Report on its Very First Narconon Program, the First of 23 Reviews or Evaluations of Results up to 2009 2Health News:Narconon Releases Report on its Very First Narconon Program, the First of 23 Reviews or Evaluations of Results up to 2009 3Health News:Narconon Releases Report on its Very First Narconon Program, the First of 23 Reviews or Evaluations of Results up to 2009 4Health News:Narconon Releases Report on its Very First Narconon Program, the First of 23 Reviews or Evaluations of Results up to 2009 5Health News:New Jersey Realtor, Lina Panza, Advocates Walkable Neighborhoods to Combat Childhood Obesity 2Health News:New Jersey Realtor, Lina Panza, Advocates Walkable Neighborhoods to Combat Childhood Obesity 3Health News:James C. Wittig, MD, Selected as one of America's Top 13 Orthopaedic Oncologists 2Health News:James C. Wittig, MD, Selected as one of America's Top 13 Orthopaedic Oncologists 3
... May 8 Neurobiological Technologies, Inc. (NTI(R)) (Nasdaq: ... three-month and nine-month periods ended March 31, 2009.Revenues for ... compared to $3.7 million for the third quarter of ... for the three months ended March 31, 2009 compared ...
... 40 mental health and child-serving organizations join SAMHSA to ... Eight young performers living with mental health challenges from ... night for a celebration of resilience. The event was ... Administration,s (SAMHSA) "HEAR ME NOW: A Celebration of Resiliency ...
... benefit from a daily exercise programme in reducing their ... An ongoing study, which began four years ago in ... assigned to daily exercise lessons reduced their overall prevalence ... of HDL-cholesterol, and reduced their systolic blood pressure. , ...
... of the Food and Drug Administration’s Adverse Event ... of tardive dyskinesia or other movement disorders reported ... generic version, metoclopramide. Tardive dyskinesia is ... of the extremities, including lip smacking, grimacing, tongue ...
... DOMA Vector and DOMA Technologies to provide Record Conversion Services to more ... the Pacific. DOMA will convert millions of veteran treatment records from ... service to our veterans while reducing cost. , ... Virginia Beach, Va. ...
... at your calendar from the past week: Have you gone ... museum?With growing evidence that these are the types of lifestyle ... the Alzheimer,s Foundation of America (AFA) has introduced a new ... that focuses on being proactive about your mental and physical ...
Cached Medicine News:Health News:Neurobiological Technologies Reports Third Quarter Fiscal 2009 Financial Results 2Health News:Neurobiological Technologies Reports Third Quarter Fiscal 2009 Financial Results 3Health News:Neurobiological Technologies Reports Third Quarter Fiscal 2009 Financial Results 4Health News:SAMHSA Honors Goldie Hawn, Youth Across the Country in Celebration of National Children's Mental Health Awareness Day 2Health News:SAMHSA Honors Goldie Hawn, Youth Across the Country in Celebration of National Children's Mental Health Awareness Day 3Health News:The cardiovascular benefits of daily exercise in school children are evident even after one year 2Health News:Analysis of FDA Adverse Events Data Reveals at Least 106 Serious Conditions Reported Among Reglan Users 2Health News:Analysis of FDA Adverse Events Data Reveals at Least 106 Serious Conditions Reported Among Reglan Users 3Health News:Analysis of FDA Adverse Events Data Reveals at Least 106 Serious Conditions Reported Among Reglan Users 4Health News:Veterans Administration Awards Small Business' $13 Million Contract to Digitize Veterans Health Records 2Health News:VIDEO from Medialink and the Alzheimer's Foundation of America: Alzheimer's Foundation Unveils Healthy Aging Web Site 2
(Date:5/21/2013)... May 21, 2013 STAAR Surgical Company (NASDAQ: ... marketer of minimally invasive ophthalmic products, today announced that ... review the Company,s recent financial results and business developments ... will present at the 38 th Annual Deutsche ... at the Westin Waterfront Hotel on Wednesday, May ...
(Date:5/21/2013)... HENDERSONVILLE, N.C. , May 21, 2013 /PRNewswire-USNewswire/ ... for home medical equipment is forcing many small and ... to lay off employees or close their businesses, developments ... products received by Medicare beneficiaries, says the American Association ... program, the Centers for Medicare & Medicaid Services ...
(Date:5/21/2013)... 2013   RxAlly , a first-of-its-kind alliance ... the publication of a white paper entitled Personalized ... The white paper highlights an unprecedented solution for ... engagement to avert strains on the health care ... a range of individually-tailored, pharmacist-provided clinical and consultative ...
Breaking Medicine Technology:STAAR Surgical To Present At Upcoming Investor Conferences 2North Carolina Business Owners At Risk Because Of Defective Medicare Bidding Program 2North Carolina Business Owners At Risk Because Of Defective Medicare Bidding Program 3North Carolina Business Owners At Risk Because Of Defective Medicare Bidding Program 4RxAlly Releases White Paper on Necessity of Personalized Pharmacist Care 2RxAlly Releases White Paper on Necessity of Personalized Pharmacist Care 3
... SPRINGFIELD, Ill., Feb. 16, 2011 Jardogs announced ... is 2011/2012 compliant and was certified as an ... Certification Commission for Health Information Technology (CCHIT®), an ... certification criteria adopted by the Secretary of Health ...
... 16, 2011 Vitality, Inc. and AT&T* have been ... AT&T connected Vitality GlowCaps . The Global Mobile ... and initiatives across the global mobile eco-system. ... in a special ceremony during the GSMA Mobile World ...
Cached Medicine Technology:Jardogs' FollowMyHealth™ Universal Health Record Receives ONC-ATCB Certification 2Jardogs' FollowMyHealth™ Universal Health Record Receives ONC-ATCB Certification 3AT&T Connected Vitality GlowCaps Wins 2011 Global Mobile Award 2AT&T Connected Vitality GlowCaps Wins 2011 Global Mobile Award 3
...
... 85") allows the surgeon to view the ... while remaining in the sterile field. ... eliminate dangling cords while maintaining longer cord ... control pouch with large particle screen accommodates ...
... Cardinal Health will change the way you ... facility. , ,Shrinking budgets and reduced reimbursements ... every turn without sacrificing the quality of ... must be evaluated from the perspective of ...
... Patient Isolation Drape features less aggressive ... aggressive adhesive strip for easy removal, ... clear, strong poly film, and product ... in a box of 5 or ...
Medicine Products: