Navigation Links
Genetic markers could predict prostate cancer in younger men, U-M study finds
Date:6/7/2010

ANN ARBOR, Mich. Prostate cancer has become more common in younger men, and it's often more aggressive in these men. A new study from researchers at the University of Michigan Comprehensive Cancer Center has found that a series of genetic mutations could help detect this early onset prostate cancer.

Researchers believe that genetics and traditional screening methods could play a role in predicting the risk of prostate cancer in younger men.

"This is a potential opportunity to combine PSA testing with genetic markers to determine who has significant prostate cancer. It could be a combination of age and family history that could help us determine who should be tested with PSA and a panel of genetic markers," says study author Kathleen Cooney, M.D., Frances and Victor Ginsberg Professor of Hematology/Oncology and division chief of hematology/oncology at the U-M Medical School.

Researchers looked for 14 different gene mutations in 754 men age 56 and younger with prostate cancer. The men were enrolled in the Prostate Cancer Genetics Project at U-M. Researchers also looked at 1,163 older men with prostate cancer and 2,713 men without prostate cancer.

The study, which was presented at the American Society of Clinical Oncology annual meeting, found that the younger men carried more of these genetic mutations. In addition, 30 percent of the younger men had aggressive prostate cancer and 41 percent of these men had at least one first-degree relative with prostate cancer.

"Early onset prostate cancer has a strong genetic component, which we saw in this study. The genetic variants we looked at here are likely not the best indicators. Our next step is to look more widely for common genetic variants among this group of men," Cooney says.


'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1

Related medicine news :

1. MSU researchers discover potential genetic factor in eating disorders
2. Jews Around the World Linked by Common Genetic Ancestry
3. Sun-induced skin cancer: new discovery permits doctors to assess genetic risk
4. Lifestyle Doesnt Influence Genetic Risks in Breast Cancer
5. Genetic differences may influence joint pain among women taking lifesaving breast cancer drugs
6. Genetic data added to archaeology and linguistics to get picture of African population history
7. Fat in Males, Females Differs Genetically, Mouse Study Shows
8. Scientists Map Genetic Codes of Human Microbes
9. Existence Genetics is Pioneering the Field of Predictive Medicine - Nexus Technologies Critical in Understanding and Preventing Deadly Disease
10. Mayo Clinic researchers find genetic secrets to common kidney cancer
11. Genetics of childrens brain tumor unlocked
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... ... May 04, 2016 , ... The manufacturer of the ... kicking trainers to St. Jude Children’s Research Hospital to benefit families dealing with ... band designed to teach children how to kick a soccer ball correctly. The ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... provider serving families of Camas and Vancouver, WA, has announced the latest ... the National Breast Cancer Foundation and their Mammography Program, which provides free ...
(Date:5/4/2016)... ... May 04, 2016 , ... IsoComforter, Inc., one ... of the innovative newly improved Iso-Hip Wrap. The newly designed hip wrap ... enhances comfort and enables the patient to enjoy the benefits of cold therapy ...
(Date:5/4/2016)... , ... May 04, 2016 , ... A new collaboration ... world. The Duke Clinical Research Institute (DCRI) and analytics leader SAS will provide researchers ... data collected by the Duke University Health System. , The DCRI and SAS ...
(Date:5/4/2016)... ... May 04, 2016 , ... Slepkow Slepkow & ... one of the top website design companies to create a state of the ... to the law firm's main practice areas. These practice areas include: real estate, ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... -- According to market research "Global Magnetic ... Demand Forecast to 2022 - Industry Insights by Architecture ... High Field, Low to Mid Field, and Ultra High ... Vascular, Breast, Pelvic and Abdomen, Cardiac, and Other)" P&S ... was valued at $5,351.7 million in 2015, and it ...
(Date:5/3/2016)... May 3, 2016 ... dass sie einen entscheidenden Meilenstein durch diese ... Aufruf zum Handeln, um Patientenresultate  bei Verdauungs- ... zu Fortschritten im Verständnis der Hepatischen Enzephalopathie ... Bewusstsein für Hepatische Enzephalopathie in der Öffentlichkeit ...
(Date:5/2/2016)...  Celsion Corporation (NASDAQ: CLSN ), an ... the first cohort of patients in its Phase ... combining GEN-1, the Company,s DNA-based immunotherapy, with the ... patients with advanced ovarian cancer who will undergo ... the first three patients dosed, GEN-1 plus standard ...
Breaking Medicine Technology: