Navigation Links
Genetic markers could predict prostate cancer in younger men, U-M study finds
Date:6/7/2010

ANN ARBOR, Mich. Prostate cancer has become more common in younger men, and it's often more aggressive in these men. A new study from researchers at the University of Michigan Comprehensive Cancer Center has found that a series of genetic mutations could help detect this early onset prostate cancer.

Researchers believe that genetics and traditional screening methods could play a role in predicting the risk of prostate cancer in younger men.

"This is a potential opportunity to combine PSA testing with genetic markers to determine who has significant prostate cancer. It could be a combination of age and family history that could help us determine who should be tested with PSA and a panel of genetic markers," says study author Kathleen Cooney, M.D., Frances and Victor Ginsberg Professor of Hematology/Oncology and division chief of hematology/oncology at the U-M Medical School.

Researchers looked for 14 different gene mutations in 754 men age 56 and younger with prostate cancer. The men were enrolled in the Prostate Cancer Genetics Project at U-M. Researchers also looked at 1,163 older men with prostate cancer and 2,713 men without prostate cancer.

The study, which was presented at the American Society of Clinical Oncology annual meeting, found that the younger men carried more of these genetic mutations. In addition, 30 percent of the younger men had aggressive prostate cancer and 41 percent of these men had at least one first-degree relative with prostate cancer.

"Early onset prostate cancer has a strong genetic component, which we saw in this study. The genetic variants we looked at here are likely not the best indicators. Our next step is to look more widely for common genetic variants among this group of men," Cooney says.


'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1

Related medicine news :

1. MSU researchers discover potential genetic factor in eating disorders
2. Jews Around the World Linked by Common Genetic Ancestry
3. Sun-induced skin cancer: new discovery permits doctors to assess genetic risk
4. Lifestyle Doesnt Influence Genetic Risks in Breast Cancer
5. Genetic differences may influence joint pain among women taking lifesaving breast cancer drugs
6. Genetic data added to archaeology and linguistics to get picture of African population history
7. Fat in Males, Females Differs Genetically, Mouse Study Shows
8. Scientists Map Genetic Codes of Human Microbes
9. Existence Genetics is Pioneering the Field of Predictive Medicine - Nexus Technologies Critical in Understanding and Preventing Deadly Disease
10. Mayo Clinic researchers find genetic secrets to common kidney cancer
11. Genetics of childrens brain tumor unlocked
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Montreal, Canada (PRWEB) , ... June 25, 2016 , ... ... the pursuit of success. In terms of the latter, setting the bar too high ... low, risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out of ... verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is ... Road To Recovery® program to drive cancer patients to and from their cancer treatments. ... the highest quality of life and ongoing independence. Getting to and from medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
(Date:6/24/2016)... ... ... Venture Construction Group (VCG) sponsors Luke’s Wings 5th ... Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event raised ... have been wounded in battle and their families. Venture Construction Group is a 2016 ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
(Date:6/23/2016)... , June 23, 2016  In a startling report released today, ... their residents by lacking a comprehensive, proven plan to eliminate prescription ... definitive ranking of how states are tackling the worst drug crisis ... four states – Kentucky , New ... Vermont . Of the 28 failing states, three – ...
(Date:6/23/2016)... Research and Markets has announced the ... 2016 - Forecast to 2022" report to their offering. ... up to date financial data derived from varied research sources ... with potential impact on the market during the next five ... comprises of sub markets, regional and country level analysis. The ...
Breaking Medicine Technology: