Navigation Links
Genetic links to impaired social behavior in autism
Date:5/13/2008

Philadelphia, PA, May 13, 2008 Individuals with autism spectrum disorders (ASD) show profound deficits in social interactions and communications, and display repetitive behaviors and abnormal responses to sensory experiences. One aspect of an autistic childs impaired social abilities is their lack of affiliative behaviors, i.e., behaviors such as touching and hugging that strengthen social bonds. On May 15th, Biological Psychiatry is publishing an article that reports new findings on genetic bases of these behaviors.

In this study, Yale University researchers recruited, genotyped, and clinically assessed a large sample of autistic children and their families. They specifically examined the genetic variants in six genes known to be involved in maternal and affiliative behaviors. Dr. Elena Grigorenko, the senior author, discusses their study, Animal studies have taught us that genetic factors can play a crucial role in the development of close affiliative ties. With the help of Yale's Autism Center of Excellence, led by Drs. Ami Klin and Fred Volkmar, and many families of individuals with ASD, we have registered a possible association between some of the genes identified in animal studies as controlling affiliative behaviors in ASD. The strongest statistical findings of the study implicate the prolactin gene, the prolactin receptor gene, and the oxytocin receptor gene in these affiliative behavior deficits.

John H. Krystal, M.D., Editor of Biological Psychiatry and affiliated with both Yale University School of Medicine and the VA Connecticut Healthcare System, comments, We are beginning to see that molecular genetics research is creating exciting new links between research in animal models and clinical disorders. The paper by Carolyn Yrigollen and colleagues suggests that two neurohormones that have been linked to affiliative behavior in animals, prolactin and oxytocin, are linked to deficits in affiliative behaviors associated with aut
'/>"/>

Contact: Jayne Dawkins
ja.dawkins@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Genetic Engineering and Biotechnology News reports on early ADMET use
2. Combined physical and genetic map finds cancers ignition key
3. Research program focuses on genetic mutations and cancer risk
4. Pelosi: Genetic Information Nondiscrimination Act Will Protect Americans from Misuse of Genetic Information
5. Genetic Changes May Dictate Course of Acute Myeloid Leukemia
6. Destruct triggers may be jammed in tumor cells, UF geneticists say
7. Inflammatory Bowel Diseases Share Some Genetic Risk Factors
8. American College of Medical Genetics Commends the Signing of the Newborn Screening Saves Lives Act
9. New genetic techniques to combat lung cancer
10. Genetic Information Nondiscrimination Act clears Senate
11. USCCB Official Praises Senate Passage of Genetic Information Nondiscrimination Act
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2014)... New York, NY (PRWEB) November 23, 2014 ... ) that allege heart attacks, strokes, deep vein ... been filed in a federal multidistrict litigation (MDL) ... Liebhard LLP reports. , Court documents updated ... on Multidistrict Litigation (JPML) show the filing of ...
(Date:11/23/2014)... 23, 2014 Locks-Magnetic.com, a notable magnetic ... Moreover, all the new products are available at low ... manager is proud of the new emergency doors. The ... And customers can choose from several colors. All of ... quality emergency door release is not as easy as ...
(Date:11/23/2014)... (PRWEB) November 23, 2014 SWAccessControl.com's high ... global market. Recently, the company has announced its new ... special offer on these high quality power suppliers. All ... 30% off. The special offer lasts until Dec. 20, ... many of them have been supporting it for a ...
(Date:11/23/2014)... (PRWEB) November 23, 2014 Asher ... Medical Aesthetics & Wellness was recently featured on ... Ph.D. is president and CEO of American Medical Aesthetics ... Asher Milgrom received a full scholarship to attend an ... Medical School at the University of Chicago, where his ...
(Date:11/23/2014)... November 23, 2014 Syngenta lawsuits are ... behalf of farmers and agribusinesses that have allegedly incurred ... commercialize Agrisure Viptera and Agrisure Duracade, genetically modified ... approved for sale in China. According to a report ... virtually ban U.S. corn imports. Because China is the ...
Breaking Medicine News(10 mins):Health News:Testosterone Lawsuits Approach 260 in Illinois Federal Court Litigation, Bernstein Liebhard LLP Reports 2Health News:Testosterone Lawsuits Approach 260 in Illinois Federal Court Litigation, Bernstein Liebhard LLP Reports 3Health News:Cheap Access Control Power Supplies Online Now at SWAccessControl.com, Special Offer Until Dec. 20, 2014 2Health News:Asher Milgrom Is the Founding Doctor of AMA Skincare and Is Featured in the International Business Times 2Health News:Asher Milgrom Is the Founding Doctor of AMA Skincare and Is Featured in the International Business Times 3Health News:Asher Milgrom Is the Founding Doctor of AMA Skincare and Is Featured in the International Business Times 4Health News:Syngenta Lawsuits Being Investigated by Wright & Schulte LLC, Following China’s Rejection of Corn Shipments Tainted with Unapproved GMO Seed 2Health News:Syngenta Lawsuits Being Investigated by Wright & Schulte LLC, Following China’s Rejection of Corn Shipments Tainted with Unapproved GMO Seed 3
... nor causes injury, according to a study presented today ... of Orthopaedic Surgeons (AAOS). More than 70 million people ... been controversy regarding whether runners should stretch before running, ... who run 10 or more miles per week. Of ...
... COLUMBIA, Mo. Most people know that exercise ... sedentary lifestyles and obesity rates are at all-time ... a new study, University of Missouri researchers found ... behavior-changing strategies significantly increased their physical activity levels. ...
... By Steven Reinberg HealthDay Reporter , THURSDAY, Feb. 17 ... start in the United States last fall, but is now circulating ... Pediatric deaths from flu tripled in the past month, jumping ... to the U.S. Centers for Disease Control and Prevention. "We ...
... walls can vary among individuals depending on factors such as ... UC Davis. The new research reinforces the link between ... can lead to heart disease and strokes. Triglycerides are ... to increase risk of inflammation of the endothelium, the layer ...
... National Women In Surgery Career Symposium will be held March ... two of the few women chairs of academic surgery programs ... will be Julie Freischlag, MD, The William Stewart Halsted Professor, ... and Nancy Ascher, MD, PhD, Isis Distinguished Professor of Transplantation ...
... (HealthDay News) -- Arthritis affected about 3.1 million Hispanics in ... wide variations in arthritis rates among Hispanic subgroups, according to ... ranged from a low of 11.7 percent among Cuban Americans ... to the analysis of National Health Interview Survey data from ...
Cached Medicine News:Health News:Stretching before a run does not prevent injury 2Health News:To increase physical activity, focus on how, not why 2Health News:U.S. Flu Season Picking Up, CDC Reports 2Health News:Study reinforces link between obesity, high-fat meals and heart disease 2Health News:National career symposium offers strategic advice to attract, advance women in surgery 2Health News:3.1 Million Hispanic Americans Struggle With Arthritis 2
(Date:11/22/2014)... , Nov. 21, 2014 Statistics released ... and drunk driving increase astronomically during the holidays, beginning ... in many cities. The data, ... Monitoring Systems as part of their annual ... paints a picture of high-risk drinking and increased rates ...
(Date:11/22/2014)... Nov. 21, 2014  Particle Sciences, Inc (PSI), ... developed and manufactured a new innovative vaginal ring ... and Development arm of Exeltis Pharmaceuticals.  According to ... Management at Particle Sciences, "This vaginal ring was ... material sciences and modeling expertise.  We are thrilled ...
(Date:11/22/2014)... 21, 2014 Many power shifts are ... influence of patients in the biopharmaceutical market is ... more than ever, understanding how to effectively acquire, ... is essential. According to recent ... companies spent about two-thirds of their patient-focused dollars ...
Breaking Medicine Technology:Alarming Stats Show Holiday Drinking an Issue for Many 2Particle Sciences' Clinical Trial Supplies Group Manufactures Innovative Vaginal Ring 2New Report Details Importance of Adopting a "Patient Journey" Framework in Marketing 2
... Brian Catlett has joined the company in the newly ... a key member of Within3,s executive team (including corporate ... provider of online community solutions for life science and ... more than 25 years of financial and operating leadership ...
... MASI ) today announced that its management is scheduled ... Conference at Terranea in Rancho Palos Verdes, California, on Thursday, ... audiocast of the presentation will be available on the Masimo ... will be available following the live presentation. ...
Cached Medicine Technology:Within3 Adds Chief Financial Officer 2Masimo to Present at Goldman Sachs 32nd Annual Global Healthcare Conference 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: