Navigation Links
Genetic health risks in children of assisted reproductive technology

More than three million children have been born as a result of assisted reproductive technologies since the birth of the first "test tube baby" in 1978. While the majority of these children are healthy and normal, as a group they are at greater risk of certain kinds of birth defects and being low birth weight, which is associated with obesity, hypertension and type 2 diabetes later in life.

Carmen Sapienza, a geneticist at Temple University School of Medicine, studies the impact of the environment on genes by comparing one type of chromosome modification, called "DNA methylation" between children conceived in the traditional fashion with children born as a result of assisted reproduction.

"We found that 5-10 percent of these chromosome modifications were different in children born through assisted reproduction, and this altered the expression of nearby genes," he said. "But we have not yet distinguished whether this is caused by assisted reproductive technologies or other factors such as the couple's infertility."

Because some of the affected genes are involved in the development of fat tissue and the metabolism of glucose, Sapienza believes it will be important to monitor these children long-term to determine whether they have higher rates of obesity or diabetes.

He notes that even though there were measurable differences in DNA methylation and gene expression between the two groups, only a small fraction of the assisted reproduction children were found to be outside the "normal" range.


Contact: Carmen Sapienza
Temple University

Page: 1

Related medicine news :

1. Scientists Spot Genetic Fingerprints of Individual Cancers
2. Penn researchers find genetic link to leukemias with an unknown origin
3. Genetic Risk Score Doesnt Spot Heart Trouble in Women
4. Study reveals genetic link between mammographic density and breast cancer
5. Epigenetic signals differ across alleles
6. Obstructive Sleep Apnea in Kids May Have Genetic Cause
7. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
8. Medco Acquires Leading Genetics Healthcare Company, DNA Direct
9. Genetic Variants in Depressed People Raise Suicide Risk
10. Discovery of epigenetic memory during breast cancer
11. St. Jude and Washington University team to unravel genetic basis of childhood cancers
Post Your Comments:
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... A ... procedures that most people are unfamiliar with. The article goes on to state that ... but also many of these less common operations such as calf and cheek reduction. ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Sessions in Dallas that it will receive two significant new grants to support ... as PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a ... second affiliate in Latin America . ... ... ... ...
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today ... Inc.,s Supplier Horizon Award . One ... Guerbet was recognized for its support of Premier members ... through clinical excellence, and commitment to lower costs. ... receive this recognition of our outstanding customer service from ...
(Date:6/23/2016)... 23, 2016 Research and Markets ... Volumes: Global Analysis (United States, China, Japan, Brazil, United ... to their offering. ... healthcare business planners, provides surgical procedure volume data in ... with an in-depth analysis of growth drivers and inhibitors, ...
Breaking Medicine Technology: