Navigation Links
Genetic disease treatments and pharmacogenetics: From scientific discovery to medical delivery
Date:11/14/2008

dy analyzed tissue samples from 413 patients and evaluated the cancerous (epithelial) and the surrounding stroma.

The researchers found 15-genetic-marker profiles that were in-common for the three cancer types and are likely to simultaneously predict or explain the cancers. Of these genetic-markers, 11 were stromal-specific, two were epithelial-specific, and two were in both compartments (epithelium and stroma). They also found a genetic-marker that was strongly associated with tumor-grade in CaP and BC only, and another one was associated with nodal metastases in BC and HNSCC only, in both compartments.

"Furthering our understanding of how multiple genetic factors interact between cancer cells and its micro-environment, or stroma, will be a valuable tool for clinicians in predicting how a cancer might spread, as well as forecasting patient outcomes," Eng stated. "Importantly, fewer molecular targets for treatment or prevention across several common carcinomas will facilitate more precise and compartment-specific therapeutic options."

Charis Eng, M.D., Ph.D., is the Director and Chair of the Cleveland Clinic Genomic Medicine Institute, and Professor and Vice Chairman of the Department of Genetics at Case Western Reserve University School of Medicine. Dr. Eng currently serves on the ASHG's Board of Directors. She also serves as Chair of the Clinical Science Committee for the Personalized Medicine Coalition (PMC).


'/>"/>

Contact: Kristen Long
klong@ashg.org
240-281-2386
American Society of Human Genetics
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. Research demonstrates differing genetic makeup of lung cancer in African-American patients
2. New technique to study the genetics of breast cancer
3. Genetic blueprint revealed for kidney design and formation
4. Know the Myths and Facts About Family Health History: American College of Medical Genetics
5. Impulse control area in brain affected in teens with genetic vulnerability for alcoholism
6. Interleukin Genetics Announces Conference Call and Webcast to Discuss Third Quarter 2008 Business Results
7. Researchers ID Genetic Markers for Esophageal Cancer
8. Genetic disorder sheds light on enzymes role in bone metabolism
9. Penn scientists map molecular regulation of fat-cell genetics
10. Tackling a hard-to-treat childhood cancer by targeting epigenetic changes
11. Tackling Hard-to-treat Childhood Cancer by Targeting Epigenetic Changes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2014)... 21, 2014 "I want to help ... back but haven’t the money for chiropractors," said an ... have such a product for myself." , The Stretch ... stretch the thigh muscles and align the spine properly. ... relieves discomfort of pinched nerves. Compact and easy to ...
(Date:9/21/2014)... September 21, 2014 The Electronic ... and supports electronic medical records (EMR) and electronic ... federal healthcare legislation during the past five years ... during the five years to 2019. The 2009 ... Act established Medicare and Medicaid incentives to encourage ...
(Date:9/21/2014)... Best Cheap Hosting USA, one of the leading ... GreenGeeks are the best Reseller hosting suppliers in 2014. ... supplier. Actually, these companies have outperformed their competitors on ... can get the best web hosting at affordable rates,” ... the manager, reseller hosting is a very popular way ...
(Date:9/21/2014)... Originally approved by the Food ... (fluticasone propionate) is a synthetic ICS therapy with ... maintenance treatment of asthma prophylactically in children and ... Diskus and HFA, which received the FDA approval ... fluticasone propionate, can bind to glucocorticoid receptors with ...
(Date:9/21/2014)... To accommodate the ever-growing customer base, Angeldress.co.uk decided to ... Recently, the company has unveiled its 2014 vintage ... wedding gowns, Angeldress.co.uk wants to make sure that all ... way. Its high quality vintage wedding outfits are now ... 62% off. , Online shopping is becoming more and ...
Breaking Medicine News(10 mins):Health News:Electronic Medical Records Systems in the US Industry Market Research Report Now Available from IBISWorld 2Health News:Electronic Medical Records Systems in the US Industry Market Research Report Now Available from IBISWorld 3Health News:Electronic Medical Records Systems in the US Industry Market Research Report Now Available from IBISWorld 4Health News:Best Cheap Hosting USA Announces The Best Reseller Hosting Suppliers In 2014 2Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 2Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 3Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 4Health News:Angeldress.co.uk Launches New Range Of 2014 Vintage Wedding Dresses In Its Online Store 2
... University of New York at the Buffalo School of Dental ... fibrinogen, a protein useful in blood clotting may increase the ... gums, those with gum disease carry certain gene variations linked ... , 79 people with gum ...
... In a landmark breakthrough, scientists have created mice with unusually ... also opening a possibility of helping people forget their distressing ... the molecular processes that govern memory and learning in the ... Technology in Zurich. , ...
... expands into Optical Coherence Tomography. This breakthrough has made many ... This has been developed by Dr. Brett Bouma an assistant ... tomography to gauge stent status.// , ... ultrasound and will allow cardiologists to view the status of ...
... on more than 1600 women reveals that parathyroid hormone (parathormone) increases ... them. The same hormone is also useful in regulating calcium levels ... new aspect of the hormone guarding against fractures has opened up ... brittle bone disease as it is also known as.// , ...
... May 24th issue of Nature reveals that the Obesity Hormone ... in more complex way than previously believed. This break through ... Obesity and many nutrition related disorders like anorexia nervosa. Dr. ... led the study. , ...
... actually repair itself by growing new cells after a heart ... York and Italy. Dr. Piero Anversa and colleagues of the ... muscle cells called myocytes continued to divide after a heart ... team examined the hearts of 13 people who died within ...
Cached Medicine News:
(Date:9/19/2014)... YORK , Sept. 19, 2014 Harwood ... against the board of directors of PDL BioPharma, Inc. ... concerning whether the board has breached its fiduciary duties ... On September 16, 2014, the Company disclosed: "On ... independent registered accounting firm, Ernst & Young LLP ("EY"), ...
(Date:9/19/2014)... WASHINGTON , Sept. 19, 2014 /PRNewswire-USNewswire/ ... often used to inflate sales of brand drugs ... Part D,  according to a new report ... Services Office of the Inspector General (OIG). Federal anti-kickback ... sales of goods that are subsidized by the ...
(Date:9/19/2014)... Calif. , Sept. 19, 2014 Today, iHealth ... capital from Xiaomi Ventures, Ltd. for its first institutional ... to continue expanding iHealth,s global reach, accelerate growth and ...  As part of the investment, Xiaomi Ventures will join ... areas of cloud infrastructure and ecommerce. "We ...
Breaking Medicine Technology:Harwood Feffer LLP Announces Investigation of PDL BioPharma, Inc. 2PCMA: New OIG Report Cites Drug Manufacturer "Copay Coupon" Use in Medicare Part D 2iHealth Raises $25 Million to Fuel Growth and Global Market Share 2
... Professional Offers Patient Tips to Guard Against,Hospital Infections, ... Hospital,infections are among the top ten leading causes ... Centers for Disease Control. There,are countless stories about ... leave under much graver circumstances. As a,patient, knowing ...
... Findings Move Science Closer to Targeted, Improved Therapies , ... on Drug Abuse (NIDA), part of the National,Institutes of ... increase a person's ability to abstain from smoking. The,breakthrough ... Research Program and a team led by Dr. Jed ...
Cached Medicine Technology:Six Important Things to Know About Preventing Hospital Infections 2Six Important Things to Know About Preventing Hospital Infections 3NIDA Study Identifies Genes That Might Help Some People Abstain,from Smoking 2NIDA Study Identifies Genes That Might Help Some People Abstain,from Smoking 3
This large 1000 L tip makes pipetting fragile cells, genomic DNA, and viscous samples easy. Perfect for cell culture laboratories....
This 1000 L tip is the equivalent to the "Blue" tips and fits nearly every manufacturer's 1000 L pipettor....
Conducting disposable filter-tips....
Designed to fit a variety of 250 L and 300 ul multi-channel pipettors, this tip offers a secure fit and extra space for repeat pipetting....
Medicine Products: