Navigation Links
Genetic differences point to ethnic and racial disparities in colorectal cancer risk
Date:11/28/2007

ATLANTA Risk of developing colorectal cancer is known to differ across ethnic and racial groups, and now an analysis of 26 studies, involving over 25,000 participants shows that some of these disparities might be explained by distinct patterns of genetic inheritance. A team of researchers, led by investigators at the University of Pittsburgh, present their findings today in Atlanta at the American Association for Cancer Research conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, being held November 27-30.

The researchers found that people who have two T copies of the gene that metabolizes folate, a chemical needed to produce and maintain new cells, are 19 percent less likely to develop colorectal cancer than are individuals with two C copies of the gene.

By using individual data collected through the Genetic Susceptibility to Environmental Carcinogens study, a collaborative pooled analysis based at the University of Pittsburgh Medical Center and begun in 1997, they were able to look at genetic inheritance in different racial and ethnic groups. The investigators found that the odds of individuals developing colorectal cancer with two T genes versus two C genes was 31 percent less in Asians, 8 percent less in Caucasians, and 4 percent more in African-Americans, although results were only statistically significant in the Asian population. Conversely, Latinos who inherited one copy of each gene instead of two C genes had a 20 percent higher risk of developing the cancer. However, this result was not statistically significant.

This analysis shows that homozygosity for the T copy of this gene may be protective in different degrees against colorectal cancer in some populations but not in others, said lead investigator, Mary A. Garza, Ph.D., M.P.H., deputy director of the Center for Minority Health in the University of Pittsburghs Graduate School of Public Health.

Ga
'/>"/>

Contact: Greg Lester
greg.lester@aacr.org
267-646-0554
American Association for Cancer Research
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. Genetic predisposition increases childhood asthma risk
3. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
4. Test Spots Genetic Damage Done by Smoking
5. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
6. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
7. Genetics Hold Promise, Challenges for Cancer Care
8. Researchers genetically engineer micro-organisms into tiny factories
9. Study Questions Genetic Screening for Treatable Diseases
10. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
11. Genetic variation affects smoking cessation treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... September 30, 2014 For Dr. Jim Pertsch, ... in San Mateo, CA, the decision was simple. “I was ... when I heard Miele offered a solution for cleaning surgical ... for ways to help the staff, and the Miele system ... and I don’t worry as much about the staff coming ...
(Date:9/30/2014)... CE-Classes.com has announced the addition of ... for Healthcare Providers. This course on treating tobacco addiction ... - substance abuse counselors, social workers, professional counselors, psychologists, ... implementation of this new course” said Ron Black, president ... smoking has tremendous value to our society.” , Appropriate ...
(Date:9/29/2014)... September 30, 2014 Shoulder pain is one ... with persistent shoulder pain generates nearly ¾ of the total ... of all adults will experience shoulder pain, and of those ... also been reported that 1 in 4 people with either ... than a year. , “This is a real problem, not ...
(Date:9/29/2014)... 30, 2014 Foundations Recovery Network, an ... the start of its 40th national conference by hosting ... a featured keynote speaker at the Moments of Change ... in the fields of addiction and mental health treatment. ... Fla., September 29 – October 2, 2014, at The ...
(Date:9/29/2014)... Boston, MA A retrospective study led by ... found an overuse of colonoscopies for colorectal cancer ... commonly recommended shorter follow-up intervals than established guidelines ... subsequent colonoscopy overuse. , "Our study shows ... being performed too early, resulting in use of ...
Breaking Medicine News(10 mins):Health News:Introducing a Safe, Time-Saving Solution for Ambulatory Surgery Centers 2Health News:Introducing a Safe, Time-Saving Solution for Ambulatory Surgery Centers 3Health News:CE-Classes.com Introduces New Online Course for Healthcare Providers 2Health News:CE-Classes.com Introduces New Online Course for Healthcare Providers 3Health News:KORT Physical Therapist Shines a Light on Shoulder Pain and Latest Treatments 2Health News:Glenn Greenwald Addresses Drug Decriminalization at Foundations Recovery Network’s 40th National Conference 2Health News:Glenn Greenwald Addresses Drug Decriminalization at Foundations Recovery Network’s 40th National Conference 3Health News:Endoscopists recommend frequent colonoscopies, leading to its overuse 2
... , , WASHINGTON, July 9 The ... the work of the National Organization on Disability,s (N.O.D.) ... emergency managers and the disability community as the only ... and personnel experienced in emergency management and disability issues. ...
... 9 The ongoing recession and associated job cuts ... employee benefit plans, slowing health insurer growth and pressuring ... and Consulting. , , "Conning projects that health ... resulting in deteriorating margins through 2011," said Terence Martin, ...
... Hospital for Special Surgery have shown that a biodegradable scaffold ... knee cartilage. The study is unique in that it used ... to examine how the plug incorporated itself into the knee. ... meeting of the American Orthopedic Society for Sports Medicine, June ...
... ... the world,s leading manufacturer and distributor of automated blood pressure monitors and health testing ... ... 2009 -- Lifeclinic International has named Lon von Hurwitz Executive Vice President ...
... externally , THURSDAY, July 9 (HealthDay News) -- U.S. ... ear infections in children. , Antibiotics are typically used ... for children with recurrent ear infections. , "The emergence ... surgical procedure raise the need to develop different ways ...
... 9 /PRNewswire-Asia-FirstCall/ -- Mindray Medical,International Limited (NYSE: ... devices worldwide, today announced that it will report its,financial ... after the U.S.,market closes on August 10, 2009. Mindray,s ... on August 11, 2009 U.S. Eastern Time (8:00 PM ...
Cached Medicine News:Health News:Walmart Foundation Commits $500,000 to Improving Emergency Preparedness for the 54 Million Americans with Disabilities 2Health News:Walmart Foundation Commits $500,000 to Improving Emergency Preparedness for the 54 Million Americans with Disabilities 3Health News:Conning Research: Health Insurance Industry Premium Growth and Profitability Under Pressure Through 2011 2Health News:Study identifies potential fix for damaged knees 2Health News:Study identifies potential fix for damaged knees 3Health News:Pioneer of Digital Place-Based Media Joins World's Leading Blood Pressure and Health Kiosk Manufacturer 2Health News:Vaccine May Someday Thwart Ear Infections 2Health News:Mindray to Report Second Quarter 2009 Financial Results on August 10, 2009 2
(Date:9/29/2014)... und SAN DIEGO , ... Company, Ltd. (nachstehend Daiichi Sankyo) (TSE: 4568) ... ) gaben heute gemeinsam eine definitive Fusionsvereinbarung ... Aktienkapital von Ambit Biosciences für 15 US-Dollar ... und anschließenden Zusammenschluss mit einem Tochterunternehmen von ...
(Date:9/29/2014)... , September 29, 2014 The ... 21.1 billion by 2018, recording a CAGR of 8.8% ... Delivery Devices Market - Global Industry Analysis, Size, Share, ... Research, a U.S.-based market intelligence company. The ... benefit from an increasing occurrence of cardiovascular diseases, diabetic ...
(Date:9/29/2014)... PRINCETON N.J. , Sept. 29, 2014 /PRNewswire/ ... agents for medical imaging, has received a Drug ... Drug Administration for its assistance in preventing or ... being recognized for its efforts related to the ... the new drug application, submitting several post-approval supplements ...
Breaking Medicine Technology:Daiichi Sankyo wird Ambit Biosciences übernehmen 2Daiichi Sankyo wird Ambit Biosciences übernehmen 3Daiichi Sankyo wird Ambit Biosciences übernehmen 4Daiichi Sankyo wird Ambit Biosciences übernehmen 5Daiichi Sankyo wird Ambit Biosciences übernehmen 6Daiichi Sankyo wird Ambit Biosciences übernehmen 7Daiichi Sankyo wird Ambit Biosciences übernehmen 8Global Implantable Drug Delivery Devices Market to Grow at 8.8% CAGR to US$ 21.1 billion by 2018: Transparency Market Research 2Global Implantable Drug Delivery Devices Market to Grow at 8.8% CAGR to US$ 21.1 billion by 2018: Transparency Market Research 3Global Implantable Drug Delivery Devices Market to Grow at 8.8% CAGR to US$ 21.1 billion by 2018: Transparency Market Research 4Guerbet Receives FDA's Drug Shortage Assistance Award: Recognized for contributions to address a shortage of Ethiodol (ethiodized oil) injection 2
... RESEARCH TRIANGLE PARK, N.C., Oct. 16 Liquidia,Technologies ... founder,and University of North Carolina-Chapel Hill professor, Joseph ... DeSimone will discuss drug delivery,applications of the PRINT(TM) ... (Logo: http://www.newscom.com/cgi-bin/prnh/20060614/CLW002LOGO ), -- ...
... went to see Dr. Peter Hersey, a medical oncologist ... was told he only had three,to six months to ... one,of the most difficult to treat forms of cancer. ... previously treated,area of his face and nothing was helping ...
Cached Medicine Technology:Targeted Nanoparticles Offer Promise in the Battle Against Cancer 2Recipient of Melanoma Drug in Development Celebrates Two Cancer-Free Years 2
Full Handle Laseredge Crescent Blade Knife, angled double bevel. Blade tip dimension: 12.7 mm x 2.0 mm x 3.8 mm....
Full Handle Laseredge Crescent Blade Knife, angled bevel up. Blade tip dimension: 12.7 mm x 2.0 mm x 3.8 mm....
Full Handle Laseredge Stab Blade Knife, 45 blade. Blade tip dimension: 8.9 mm x 1.9 mm x 1.9 mm....
Full Handle Laseredge Stab Blade Knife, 15 blade. Blade tip dimension: 3 mm x 1.0 mm x 3.0 mm....
Medicine Products: