Navigation Links
Genetic differences point to ethnic and racial disparities in colorectal cancer risk
Date:11/28/2007

ATLANTA Risk of developing colorectal cancer is known to differ across ethnic and racial groups, and now an analysis of 26 studies, involving over 25,000 participants shows that some of these disparities might be explained by distinct patterns of genetic inheritance. A team of researchers, led by investigators at the University of Pittsburgh, present their findings today in Atlanta at the American Association for Cancer Research conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, being held November 27-30.

The researchers found that people who have two T copies of the gene that metabolizes folate, a chemical needed to produce and maintain new cells, are 19 percent less likely to develop colorectal cancer than are individuals with two C copies of the gene.

By using individual data collected through the Genetic Susceptibility to Environmental Carcinogens study, a collaborative pooled analysis based at the University of Pittsburgh Medical Center and begun in 1997, they were able to look at genetic inheritance in different racial and ethnic groups. The investigators found that the odds of individuals developing colorectal cancer with two T genes versus two C genes was 31 percent less in Asians, 8 percent less in Caucasians, and 4 percent more in African-Americans, although results were only statistically significant in the Asian population. Conversely, Latinos who inherited one copy of each gene instead of two C genes had a 20 percent higher risk of developing the cancer. However, this result was not statistically significant.

This analysis shows that homozygosity for the T copy of this gene may be protective in different degrees against colorectal cancer in some populations but not in others, said lead investigator, Mary A. Garza, Ph.D., M.P.H., deputy director of the Center for Minority Health in the University of Pittsburghs Graduate School of Public Health.

Ga
'/>"/>

Contact: Greg Lester
greg.lester@aacr.org
267-646-0554
American Association for Cancer Research
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. Genetic predisposition increases childhood asthma risk
3. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
4. Test Spots Genetic Damage Done by Smoking
5. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
6. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
7. Genetics Hold Promise, Challenges for Cancer Care
8. Researchers genetically engineer micro-organisms into tiny factories
9. Study Questions Genetic Screening for Treatable Diseases
10. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
11. Genetic variation affects smoking cessation treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... (PRWEB) , ... July 29, 2015 , ... The insurance ... of automakers. This would allow insurers to access the on-board vehicle data and better ... reticent when it comes to sharing vehicle data. However times are changing and automakers ...
(Date:7/28/2015)... ... July 28, 2015 , ... ProFont is back with a whole new ... ProFont: Cursive users can generate a hand drawn feel all with a click of ... can select from either the upper and lowercase alphabet, special characters, numbers, and stylized ...
(Date:7/28/2015)... Rolling Meadows, Ill. (PRWEB) , ... July 28, 2015 , ... ... has been commended with a national 2015 Power of A award for “helping to ... named a Power of A Gold Award winner by the American Society of Association ...
(Date:7/28/2015)... , ... July 28, 2015 , ... ... products, announces Skimmer Helper, a household invention that cleans pools efficiently - minus ... billion," says Scott Cooper, CEO and Creative Director of World Patent Marketing. "It ...
(Date:7/28/2015)... ... ... Mindful Her, a unique women’s wellness and lifestyle event designed to inspire and ... the next level, announced today an influential line-up of inspiring speakers, including Mallika Chopra, ... an Orange County based non-profit that works locally and globally to help girls become ...
Breaking Medicine News(10 mins):Health News:General Motors Engaging Insurance Partners for the Connected Car 2Health News:General Motors Engaging Insurance Partners for the Connected Car 3Health News:Announcing ProFont Cursive from FCPX Effects developer Pixel Film Studios 2Health News:ASDS Skin Cancer Program Honored 2Health News:ASDS Skin Cancer Program Honored 3Health News:10 Fascinating Things You Never Knew About Swimming Pools Is Introduced by World Patent Marketing and Skimmer Helper 2Health News:10 Fascinating Things You Never Knew About Swimming Pools Is Introduced by World Patent Marketing and Skimmer Helper 3Health News:10 Fascinating Things You Never Knew About Swimming Pools Is Introduced by World Patent Marketing and Skimmer Helper 4Health News:10 Fascinating Things You Never Knew About Swimming Pools Is Introduced by World Patent Marketing and Skimmer Helper 5Health News:Women’s Healthy Living Event Mindful Her Set for October 24, 2015 in Orange County 2Health News:Women’s Healthy Living Event Mindful Her Set for October 24, 2015 in Orange County 3
... is a wealth of scientific literature available on the ... is a paucity of data to guide the treatment ... U.S. Food and Drug Administration (FDA) has recently approved ... schizophrenia, few controlled data are available to help guide ...
... dermatologist endorsed moisturizers, MEMPHIS, Tenn., Feb. 28 ... line of dermatologist endorsed moisturizers especially,created to treat ... its 2008,"Prepare to Unveil Yourself" initiative with expert ... Four Theraplex(R) solutions:,HydroLotion, ClearLotion, Emollient, and Theraplex FT ...
... New Jersey State Nurses Association (NJSNA) awarded its 2008 ... in Research to Rutgers College of Nursing faculty member ... of Nursing at Rutgers, The State University of New ... recipients during the NJSNA awards banquet during the New ...
... Feb. 28 Boston Scientific,Corporation (NYSE: ... implants of its,COGNIS(TM) cardiac resynchronization therapy defibrillator ... began,performing implants earlier this week. Forty implants ... countries., When choosing a high-energy device, ...
... NightHawk,Radiology Holdings, Inc. (Nasdaq: NHWK ), the leading ... the United States,today announced that it will present at ... Tuesday, March 18, 2008, at 11:00 am EDT at ... Berger, Chairman and,Chief Executive Officer, Andrea Clegg, Vice President ...
... Fuller, COTO DE CAZA, Calif., Feb. 28 ... that it,will premier its newest product, Athena Lash Serum, ... America,s Beauty Show is one of the largest,and finest ... Lash Serum is the new generation of eyelash conditioner. ...
Cached Medicine News:Health News:Comparison of antipsychotic treatments in adolescents with schizophrenia 2Health News:Prepare to Unveil Yourself with Theraplex(R) for Spring and Summer 2008 2Health News:Prepare to Unveil Yourself with Theraplex(R) for Spring and Summer 2008 3Health News:Prepare to Unveil Yourself with Theraplex(R) for Spring and Summer 2008 4Health News:Boston Scientific Announces First European Implants of New Devices to Treat Heart Failure and Sudden Cardiac Death 2Health News:Boston Scientific Announces First European Implants of New Devices to Treat Heart Failure and Sudden Cardiac Death 3Health News:Boston Scientific Announces First European Implants of New Devices to Treat Heart Failure and Sudden Cardiac Death 4Health News:NightHawk Radiology Holdings, Inc. to Speak at the Cowen and Company 28th Annual Health Care Conference on March 18, 2008 2Health News:Athena Lash Serum Premiers at America's Beauty Show, Chicago 2
(Date:7/29/2015)... According to a new market ... Trends & Forecasts (2015-2020) , published by Mordor Intelligence, ... 2.85 billion by the end of 2020, with ... globally accounting for more than 36% of the global ... expected to grow at a CAGR of 44.6% during ...
(Date:7/28/2015)... , July 28, 2015  Insulet Corporation (NASDAQ: ... with its OmniPod ® Insulin Management System, today ... appointed to Insulet,s Board of Directors. Dr. ... experience to the Insulet Board. She currently serves as ... Diabetes Center, the world,s largest diabetes research center, diabetes ...
(Date:7/28/2015)... 28, 2015   Regulus Therapeutics Inc . ( ... and development of innovative medicines targeting microRNAs, today announced ... the quarter ended June 30, 2015 on Tuesday, August ... Regulus will host a conference call and ... Eastern Daylight Time to discuss its second quarter 2015 ...
Breaking Medicine Technology:New Approaches and Technical Advances by Major Players Like Novartis, Merck KGaA, Pfizer, GlaxoSmithKline and Others to Elevate the Global Therapeutic Vaccines Market 2New Approaches and Technical Advances by Major Players Like Novartis, Merck KGaA, Pfizer, GlaxoSmithKline and Others to Elevate the Global Therapeutic Vaccines Market 3Insulet Appoints Jessica Hopfield, PhD, to Board of Directors 2Insulet Appoints Jessica Hopfield, PhD, to Board of Directors 3Regulus Announces Timing for Second Quarter 2015 Financial Results Webcast and Conference Call 2Regulus Announces Timing for Second Quarter 2015 Financial Results Webcast and Conference Call 3
1.0% Casein digest (NZ amine), 0.5% Sodium Chloride....
0.5% Yeast Extract, 2.0% Tryp, 10mM Sodium Chloride, 2.5mM Potassium Chloride, 10mM Magnesium Chloride, 10mM Mag. Sulfate....
S.O.C. Medium...
3.2% Tryptone, 2.0% Yeast Extract, 0.5% Sodium Chloride, pH 7.5....
Medicine Products: