Navigation Links
Genetic differences point to ethnic and racial disparities in colorectal cancer risk
Date:11/28/2007

ATLANTA Risk of developing colorectal cancer is known to differ across ethnic and racial groups, and now an analysis of 26 studies, involving over 25,000 participants shows that some of these disparities might be explained by distinct patterns of genetic inheritance. A team of researchers, led by investigators at the University of Pittsburgh, present their findings today in Atlanta at the American Association for Cancer Research conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, being held November 27-30.

The researchers found that people who have two T copies of the gene that metabolizes folate, a chemical needed to produce and maintain new cells, are 19 percent less likely to develop colorectal cancer than are individuals with two C copies of the gene.

By using individual data collected through the Genetic Susceptibility to Environmental Carcinogens study, a collaborative pooled analysis based at the University of Pittsburgh Medical Center and begun in 1997, they were able to look at genetic inheritance in different racial and ethnic groups. The investigators found that the odds of individuals developing colorectal cancer with two T genes versus two C genes was 31 percent less in Asians, 8 percent less in Caucasians, and 4 percent more in African-Americans, although results were only statistically significant in the Asian population. Conversely, Latinos who inherited one copy of each gene instead of two C genes had a 20 percent higher risk of developing the cancer. However, this result was not statistically significant.

This analysis shows that homozygosity for the T copy of this gene may be protective in different degrees against colorectal cancer in some populations but not in others, said lead investigator, Mary A. Garza, Ph.D., M.P.H., deputy director of the Center for Minority Health in the University of Pittsburghs Graduate School of Public Health.

Ga
'/>"/>

Contact: Greg Lester
greg.lester@aacr.org
267-646-0554
American Association for Cancer Research
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. Genetic predisposition increases childhood asthma risk
3. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
4. Test Spots Genetic Damage Done by Smoking
5. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
6. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
7. Genetics Hold Promise, Challenges for Cancer Care
8. Researchers genetically engineer micro-organisms into tiny factories
9. Study Questions Genetic Screening for Treatable Diseases
10. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
11. Genetic variation affects smoking cessation treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/1/2015)... ... July 01, 2015 , ... During the first ... National Sales Training and Development) and Chuck Corso (Associate Sales Trainer) participated in ... AZ. LTEN brings together learning and development professionals from more than 300 life ...
(Date:7/1/2015)... ... - (PRWEB) July 01, 2015 , ... Lisa Keys, the widow of U.S. ... 15-16th (MSG Keys’ birthday) in memory of her late husband and all of America’s ... of the Bronze Star Medal, died during a Special Forces training exercise in December ...
(Date:7/1/2015)... , ... July 01, 2015 , ... ... said lead author Lisa Stolzenberg, a Professor in FIU’s School of International and ... 12 to 17 years who participated in the National Survey on Drug Use ...
(Date:7/1/2015)... ... ... Scoliosis is a disorder in which the normally straight vertical line of the spine curves ... of the population, or an estimated 6 to 9 million people. While it is found ... 10 and 15. Most types of scoliosis are more common in girls than in boys. ...
(Date:7/1/2015)... ... July 01, 2015 , ... Boar’s ... helping families get ready for Independence Day celebrations with new takes on classic ... versatile options are perfect for any summertime get together. , “Celebrating with family, ...
Breaking Medicine News(10 mins):Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 2Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 3Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 4Health News:Wife of Fallen Special Forces Soldier to Host Nationwide ‘Virtual 5K’ for Charity 2Health News:Wife of Fallen Special Forces Soldier to Host Nationwide ‘Virtual 5K’ for Charity 3Health News:Researchers find that medical marijuana laws increase recreational marijuana use among juveniles 2Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 2Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 3Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 4Health News:Boar’s Head Helps Craft a Delicious Independence Day 2Health News:Boar’s Head Helps Craft a Delicious Independence Day 3
... ... to Become First Person to Travel from Canada to Hawaii Under His Own Power – ... Calgary, Alberta (PRWEB) February ... become the first person ever to travel from Canada to Hawaii under his own power. ...
... , Feb. 4 The Global AIDS Alliance (GAA) ... the International Violence Against Women Act (I-VAWA) today. Violence against women ... to access healthcare globally. I-VAWA provides an essential tool in ... an insidious and pervasive challenge to the ability of women and ...
... , WASHINGTON , ... Shots to Save Lives , released today by the Trust for America,s ... Wood Johnson Foundation (RWJF), found that more than 30 percent of adults ... states as of 2008.  The U.S. Centers for Disease Control and Prevention ...
... , WASHINGTON ... The Independent Budget (IB) —AMVETS, Disabled American Veterans, ... who collectively represent millions of veterans—are applauding the Administration,s ... request includes significant funding increases for Department of Veterans ...
... , , ORLANDO, ... Townshend donated his guitar to Hard Rock and helped to start ... Super Bowl XLIV halftime performers The Who are once again making Hard ... The Who Signature Series: Edition XXVII , designed by Pete Townshend ...
... N.J. , Feb. 4 Verizon Wireless, the company ... data network, said today that it is participating in text4baby – ... pregnant women and new moms through a baby,s first year.   ... "BABY" to 511411 (or "BEBE" for Spanish) to receive three free ...
Cached Medicine News:Health News:Adventurer Sets Sea Trial for World Record Human-Powered Ocean Crossing from Canada to Hawaii 2Health News:Adventurer Sets Sea Trial for World Record Human-Powered Ocean Crossing from Canada to Hawaii 3Health News:Global Aids Alliance Celebrates the Introduction of the International Violence Against Women Act, Urges Swift Passage 2Health News:Global Aids Alliance Celebrates the Introduction of the International Violence Against Women Act, Urges Swift Passage 3Health News:More than 30 Percent of Seniors Are Not Immunized Against Pneumonia in 36 States; New Report Finds Low Adult Vaccination Rates in U.S. 2Health News:More than 30 Percent of Seniors Are Not Immunized Against Pneumonia in 36 States; New Report Finds Low Adult Vaccination Rates in U.S. 3Health News:More than 30 Percent of Seniors Are Not Immunized Against Pneumonia in 36 States; New Report Finds Low Adult Vaccination Rates in U.S. 4Health News:More than 30 Percent of Seniors Are Not Immunized Against Pneumonia in 36 States; New Report Finds Low Adult Vaccination Rates in U.S. 5Health News:More than 30 Percent of Seniors Are Not Immunized Against Pneumonia in 36 States; New Report Finds Low Adult Vaccination Rates in U.S. 6Health News:More than 30 Percent of Seniors Are Not Immunized Against Pneumonia in 36 States; New Report Finds Low Adult Vaccination Rates in U.S. 7Health News:Administration's Budget Affirms Commitment to Veterans, say Coauthors of The Independent Budget 2Health News:Administration's Budget Affirms Commitment to Veterans, say Coauthors of The Independent Budget 3Health News:Administration's Budget Affirms Commitment to Veterans, say Coauthors of The Independent Budget 4Health News:The Who Designs Limited-Edition T-Shirt Exclusively for Hard Rock's Signature Series: Edition XXVII 2Health News:The Who Designs Limited-Edition T-Shirt Exclusively for Hard Rock's Signature Series: Edition XXVII 3Health News:The Who Designs Limited-Edition T-Shirt Exclusively for Hard Rock's Signature Series: Edition XXVII 4Health News:The Who Designs Limited-Edition T-Shirt Exclusively for Hard Rock's Signature Series: Edition XXVII 5Health News:Verizon Wireless Supports Text4baby Program 2Health News:Verizon Wireless Supports Text4baby Program 3
(Date:7/1/2015)... According to a new market research report ... Synthetic, Fibrin, Collagen, Gelatin, Cyanoacrylate, Polymeric, Polyurethane), by Application ... 2020", published by MarketsandMarkets, the global Surgical Sealants and ... 2020, growing at a CAGR of 9.2% during the ... 119 market T ables and 29 ...
(Date:7/1/2015)... HONG KONG and FT LAUDERDALE, Florida ... Medical, Inc. ("OrbusNeich"), a designer, developer, manufacturer and marketer of ... today that on May 13, 2015, it prevailed in a ... regarding European Patent EP 1 341 482 - STENT HAVING ... level of review in the EPO and has been upheld ...
(Date:7/1/2015)... Pharma, Inc. (Nasdaq: MEIP ), an oncology company focused ... today that Daniel P. Gold , Ph.D., President and ... Healthcare Conference on Wednesday, July 8, 2015 at 8:30 a.m. ... New York . A live webcast of the ... will be available approximately one hour after the presentation. ...
Breaking Medicine Technology:Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 2Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 3Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 4OrbusNeich Announces Favorable Ruling from the European Patent Office and Initiation of Litigation Against Terumo Corporation 2MEI Pharma to Present at Cantor Fitzgerald Healthcare Conference 2
... , INDIANAPOLIS, Nov. 2 Arcadia Resources, Inc. (NYSE Amex: ... care services under the Arcadia HealthCare(SM) brand, today announced President ... present at the Lazard Capital Markets Sixth Annual Healthcare Conference ... , Arcadia will present its story to institutional investors in ...
... of Tamiflu in liquid form has contributed to some dosage ... the contents of the Tamiflu pill form when developing their ... Nov. 2 Two pediatric patients in Pennsylvania ... flu symptoms because of unawareness among staff as to the ...
Cached Medicine Technology:Arcadia Resources to Present at Lazard Healthcare Conference in New York 2Alert: Two Overdoses of Tamiflu in Pediatric Patients in Pennsylvania 2
... test is a rapid immunochromatographic screening test ... cruzi. It can be used with ... employs a unique combination of a specific ... dye particles, and antigens which are bound ...
Sprint Quattro Secure™ is a Steroid-Eluting, True Bipolar, Active Fixation ICD Lead....
... Medtronic Subcutaneous Lead System Model ... with the use of the ... Improved SQ design and implant ... fast and easy procedure, and ...
... defibrillator lead features a patented ... flexibility and maneuverability of a ... physician who prefers a lead ... SPL lead also promotes low ...
Medicine Products: